1.0 2016-09-30 22:45:43 UTC 2020-05-21 16:28:30 UTC BMDB0001422 BMDB01422 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine is possibly soluble (in water) and a very strong basic compound (based on its pKa). 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine exists in all living organisms, ranging from bacteria to humans. 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine participates in a number of enzymatic reactions, within cattle. In particular, 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine and succinic acid can be biosynthesized from N6,N6,N6-trimethyl-L-lysine and oxoglutaric acid through its interaction with the enzyme trimethyllysine dioxygenase, mitochondrial. In addition, 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine can be converted into glycine and 4-trimethylammoniobutanal; which is mediated by the enzyme serine hydroxymethyltransferase, cytosolic. In cattle, 3-hydroxy-N6,N6,N6-trimethyl-L-lysine is involved in the metabolic pathway called carnitine synthesis pathway. 3-Hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine 3-Hydroxy-N(6),N(6),N(6)-trimethyllysine 3-Hydroxy-N6,N6,N6-trimethyl-L-lysin-N6-ium C9H21N2O3 205.2746 205.155217548 [(5S)-5-amino-5-carboxy-4-hydroxypentyl]trimethylazanium [(5S)-5-amino-5-carboxy-4-hydroxypentyl]trimethylazanium C[N+](C)(C)CCCC(O)[C@H](N)C(O)=O InChI=1S/C9H20N2O3/c1-11(2,3)6-4-5-7(12)8(10)9(13)14/h7-8,12H,4-6,10H2,1-3H3/p+1/t7?,8-/m0/s1 ZRJHLGYVUCPZNH-MQWKRIRWSA-O belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues L-alpha-amino acids Amino acids Amino fatty acids Beta hydroxy acids and derivatives Carbonyl compounds Carboxylic acids Hydrocarbon derivatives Hydroxy fatty acids Medium-chain fatty acids Medium-chain hydroxy acids and derivatives Monoalkylamines Monocarboxylic acids and derivatives Organic cations Organic oxides Organic salts Organopnictogen compounds Secondary alcohols Tetraalkylammonium salts Alcohol Aliphatic acyclic compound Amine Amino acid Amino fatty acid Beta-hydroxy acid Carbonyl group Carboxylic acid Fatty acid Fatty acyl Hydrocarbon derivative Hydroxy acid Hydroxy fatty acid L-alpha-amino acid Medium-chain fatty acid Medium-chain hydroxy acid Monocarboxylic acid or derivatives Organic cation Organic nitrogen compound Organic oxide Organic oxygen compound Organic salt Organonitrogen compound Organooxygen compound Organopnictogen compound Primary aliphatic amine Primary amine Quaternary ammonium salt Secondary alcohol Tetraalkylammonium salt Aliphatic acyclic compounds alpha-amino-acid cation Solid logp -2.88 ALOGPS logs -2.12 ALOGPS logp -7.1 ChemAxon pka_strongest_acidic 2.2 ChemAxon pka_strongest_basic 8.99 ChemAxon iupac [(5S)-5-amino-5-carboxy-4-hydroxypentyl]trimethylazanium ChemAxon average_mass 205.2746 ChemAxon mono_mass 205.155217548 ChemAxon smiles C[N+](C)(C)CCCC(O)[C@H](N)C(O)=O ChemAxon formula C9H21N2O3 ChemAxon inchi InChI=1S/C9H20N2O3/c1-11(2,3)6-4-5-7(12)8(10)9(13)14/h7-8,12H,4-6,10H2,1-3H3/p+1/t7?,8-/m0/s1 ChemAxon inchikey ZRJHLGYVUCPZNH-MQWKRIRWSA-O ChemAxon polar_surface_area 83.55 ChemAxon refractivity 65.15 ChemAxon polarizability 22.75 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 4 ChemAxon donor_count 3 ChemAxon physiological_charge 1 ChemAxon formal_charge 1 ChemAxon number_of_rings 0 ChemAxon bioavailability 1 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Carnitine Synthesis SMP0087187 Specdb::CMs 23937 Specdb::CMs 38067 Specdb::CMs 157435 Specdb::MsMs 319060 Specdb::MsMs 319061 Specdb::MsMs 319062 Specdb::MsMs 2326293 Specdb::MsMs 2326294 Specdb::MsMs 2326295 C01259 388565 FDB022613 439460 15786 37211 6234 BMDBP00087 Serine hydroxymethyltransferase, cytosolic Q5E9P9 SHMT1 Enzyme BMDBP00622 Trimethyllysine dioxygenase, mitochondrial Q0VC74 TMLHE Enzyme