1.0 2016-09-30 22:54:30 UTC 2020-05-11 20:02:41 UTC BMDB0002356 BMDB02356 Hexacosanoic acid Hexacosanoic acid, also known as Hexacosanoic acid or Hexacosanoic acid, belongs to the class of organic compounds known as very long-chain fatty acids. These are fatty acids with an aliphatic tail that contains at least 22 carbon atoms. Hexacosanoic acid exists as a solid, very hydrophobic, practically insoluble (in water), and relatively neutral molecule. Hexacosanoic acid exists in all eukaryotes, ranging from yeast to humans. In cattle, hexacosanoic acid is involved in the metabolic pathway called the Beta oxidation OF very long chain fatty acids pathway. Hexacosanoic acid is a potentially toxic compound. C26:0 Ceratinic acid Ceric acid Cerinic acid Cerotic acid Cerotinic acid Cerylic acid CH3-[CH2]24-COOH Hexacosansaeure Hexacosoic acid Hexaeicosanoic acid N-C26:0 N-Hexacosanoic acid Ceratinate Cerate Cerinate Cerotate Cerotinate Cerylate Hexacosoate Hexaeicosanoate N-Hexacosanoate Hexacosanoate Hexacosanoate (N-C26:0) Hexacosanoic acid FA(26:0) C26H52O2 396.6899 396.396730908 hexacosanoic acid hexacosanoic acid 506-46-7 CCCCCCCCCCCCCCCCCCCCCCCCCC(O)=O InChI=1S/C26H52O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26(27)28/h2-25H2,1H3,(H,27,28) XMHIUKTWLZUKEX-UHFFFAOYSA-N belongs to the class of organic compounds known as very long-chain fatty acids. These are fatty acids with an aliphatic tail that contains at least 22 carbon atoms. Organic compounds Lipids and lipid-like molecules Fatty Acyls Fatty acids and conjugates Very long-chain fatty acids Carbonyl compounds Carboxylic acids Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Straight chain fatty acids Aliphatic acyclic compound Carbonyl group Carboxylic acid Carboxylic acid derivative Hydrocarbon derivative Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organooxygen compound Straight chain fatty acid Very long-chain fatty acid Aliphatic acyclic compounds Straight chain fatty acids straight-chain saturated fatty acid very long-chain fatty acid Solid melting_point 88.5 °C logp 9.87 ALOGPS logs -7.34 ALOGPS logp 10.7 ChemAxon pka_strongest_acidic 4.95 ChemAxon iupac hexacosanoic acid ChemAxon average_mass 396.6899 ChemAxon mono_mass 396.396730908 ChemAxon smiles CCCCCCCCCCCCCCCCCCCCCCCCCC(O)=O ChemAxon formula C26H52O2 ChemAxon inchi InChI=1S/C26H52O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26(27)28/h2-25H2,1H3,(H,27,28) ChemAxon inchikey XMHIUKTWLZUKEX-UHFFFAOYSA-N ChemAxon polar_surface_area 37.3 ChemAxon refractivity 123.09 ChemAxon polarizability 55.83 ChemAxon rotatable_bond_count 24 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon number_of_rings 0 ChemAxon bioavailability 0 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Beta Oxidation of Very Long Chain Fatty Acids SMP0087259 Specdb::CMs 2226 Specdb::CMs 3233 Specdb::CMs 31413 Specdb::CMs 31677 Specdb::CMs 31987 Specdb::CMs 38386 Specdb::CMs 155239 Specdb::EiMs 107 Specdb::NmrTwoD 1816 Specdb::NmrOneD 1879 Specdb::NmrOneD 2415 Specdb::NmrOneD 3105 Specdb::MsMs 2076 Specdb::MsMs 2077 Specdb::MsMs 2078 Specdb::MsMs 179739 Specdb::MsMs 179740 Specdb::MsMs 179741 Specdb::MsMs 182073 Specdb::MsMs 182074 Specdb::MsMs 182075 Specdb::MsMs 1471323 Specdb::MsMs 2455027 Specdb::MsMs 2455028 Specdb::MsMs 2455029 Specdb::MsMs 2484438 Specdb::MsMs 2484439 Specdb::MsMs 2484440 Adrenal Gland Wishart DS, Feunang YD, Marcu A, Guo AC, Liang K, Vazquez-Fresno R, Sajed T, Johnson D, Li C, Karu N, Sayeeda Z, Lo E, Assempour N, Berjanskii M, Singhal S, Arndt D, Liang Y, Badran H, Grant J, Serra-Cayuela A, Liu Y, Mandal R, Neveu V, Pon A, Knox C, Wilson M, Manach C, Scalbert A: HMDB 4.0: the human metabolome database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D608-D617. doi: 10.1093/nar/gkx1089. 29140435 Fibroblasts Wishart DS, Feunang YD, Marcu A, Guo AC, Liang K, Vazquez-Fresno R, Sajed T, Johnson D, Li C, Karu N, Sayeeda Z, Lo E, Assempour N, Berjanskii M, Singhal S, Arndt D, Liang Y, Badran H, Grant J, Serra-Cayuela A, Liu Y, Mandal R, Neveu V, Pon A, Knox C, Wilson M, Manach C, Scalbert A: HMDB 4.0: the human metabolome database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D608-D617. doi: 10.1093/nar/gkx1089. 29140435 Mammary Gland 8 multiparous Chinese Holstein dairy cows fed in the Hangzhou Hangjiang Dairy Farm based on the milk production under corn stover based diets. Detection used gas chromatography time-of-flight/mass spectrometry (GC-TOF/MS) platform. Sun HZ, Zhou M, Wang O, Chen Y, Liu JX, Guan LL: Multi-omics reveals functional genomic and metabolic mechanisms of milk production and quality in dairy cows. Bioinformatics. 2020 Apr 15;36(8):2530-2537. doi: 10.1093/bioinformatics/btz951. 31873721 Mammary Gland 8 multiparous Chinese Holstein dairy cows fed in the Hangzhou Hangjiang Dairy Farm based on the milk production under alfalfa hay based diets. Detection used gas chromatography time-of-flight/mass spectrometry (GC-TOF/MS) platform. Sun HZ, Zhou M, Wang O, Chen Y, Liu JX, Guan LL: Multi-omics reveals functional genomic and metabolic mechanisms of milk production and quality in dairy cows. Bioinformatics. 2020 Apr 15;36(8):2530-2537. doi: 10.1093/bioinformatics/btz951. 31873721 FDB004035 10037 10469 31009 C00035114 1459812 Cerotic acid 6642 Tsuji S; Sano T; Ariga T; Miyatake T Increased synthesis of hexacosanoic acid (C23:0) by cultured skin fibroblasts from patients with adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN). Journal of biochemistry (1981), 90(4), 1233-6.