1.0 2016-09-30 23:07:09 UTC 2020-05-21 16:29:05 UTC BMDB0003971 BMDB03971 Beta-D-Fructose 6-phosphate Beta-D-Fructose 6-phosphate, also known as b-D-fructose 6-phosphoric acid or 6-O-phosphono-b-D-fructofuranose, belongs to the class of organic compounds known as pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups. Beta-D-Fructose 6-phosphate is possibly soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Beta-D-Fructose 6-phosphate exists in all living species, ranging from bacteria to humans. Beta-D-Fructose 6-phosphate participates in a number of enzymatic reactions, within cattle. In particular, Beta-D-Fructose 6-phosphate can be biosynthesized from D-fructose through the action of the enzyme hexokinase-2. In addition, Beta-D-Fructose 6-phosphate can be converted into glucose 6-phosphate through its interaction with the enzyme glucose-6-phosphate isomerase. In cattle, Beta-D-fructose 6-phosphate is involved in the metabolic pathway called the starch and sucrose metabolism pathway. 6-O-Phosphono-beta-D-fructofuranose FRUCTOSE-6-phosphATE 6-O-Phosphono-b-D-fructofuranose 6-O-Phosphono-β-D-fructofuranose FRUCTOSE-6-phosphoric acid b-D-Fructose 6-phosphate b-D-Fructose 6-phosphoric acid beta-D-Fructose 6-phosphoric acid Β-D-fructose 6-phosphate Β-D-fructose 6-phosphoric acid C6H13O9P 260.1358 260.029718526 {[(2R,3S,4S,5R)-3,4,5-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methoxy}phosphonic acid β-D-fructofuranose 6-phosphate OC[C@@]1(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O InChI=1S/C6H13O9P/c7-2-6(10)5(9)4(8)3(15-6)1-14-16(11,12)13/h3-5,7-10H,1-2H2,(H2,11,12,13)/t3-,4-,5+,6-/m1/s1 BGWGXPAPYGQALX-ARQDHWQXSA-N belongs to the class of organic compounds known as pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups. Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates Pentose phosphates C-glycosyl compounds Hemiacetals Hydrocarbon derivatives Monoalkyl phosphates Monosaccharide phosphates Organic oxides Oxacyclic compounds Polyols Primary alcohols Secondary alcohols Tetrahydrofurans Alcohol Aliphatic heteromonocyclic compound Alkyl phosphate C-glycosyl compound Glycosyl compound Hemiacetal Hydrocarbon derivative Monoalkyl phosphate Monosaccharide phosphate Organic oxide Organic phosphoric acid derivative Organoheterocyclic compound Oxacycle Pentose phosphate Pentose-5-phosphate Phosphoric acid ester Polyol Primary alcohol Secondary alcohol Tetrahydrofuran Aliphatic heteromonocyclic compounds D-fructofuranose 6-phosphate Solid logp -2.11 ALOGPS logs -0.89 ALOGPS logp -2.9 ChemAxon pka_strongest_acidic 1.22 ChemAxon pka_strongest_basic -3.5 ChemAxon iupac {[(2R,3S,4S,5R)-3,4,5-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methoxy}phosphonic acid ChemAxon average_mass 260.1358 ChemAxon mono_mass 260.029718526 ChemAxon smiles OC[C@@]1(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O ChemAxon formula C6H13O9P ChemAxon inchi InChI=1S/C6H13O9P/c7-2-6(10)5(9)4(8)3(15-6)1-14-16(11,12)13/h3-5,7-10H,1-2H2,(H2,11,12,13)/t3-,4-,5+,6-/m1/s1 ChemAxon inchikey BGWGXPAPYGQALX-ARQDHWQXSA-N ChemAxon polar_surface_area 156.91 ChemAxon refractivity 47.23 ChemAxon polarizability 20.92 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 8 ChemAxon donor_count 6 ChemAxon physiological_charge -2 ChemAxon formal_charge 0 ChemAxon number_of_rings 1 ChemAxon bioavailability 1 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Starch and Sucrose Metabolism SMP0087252 Specdb::MsMs 23189 Specdb::MsMs 23190 Specdb::MsMs 23191 Specdb::MsMs 29987 Specdb::MsMs 29988 Specdb::MsMs 29989 Specdb::MsMs 438854 Specdb::MsMs 438855 Specdb::MsMs 438856 Specdb::MsMs 2339946 Specdb::MsMs 2339947 Specdb::MsMs 2339948 Specdb::MsMs 2626412 Specdb::MsMs 2626413 Specdb::MsMs 2626414 Specdb::NmrOneD 35262 Specdb::NmrOneD 35263 Specdb::NmrOneD 35264 Specdb::NmrOneD 35265 Specdb::NmrOneD 35266 Specdb::NmrOneD 35267 Specdb::NmrOneD 35268 Specdb::NmrOneD 35269 Specdb::NmrOneD 35270 Specdb::NmrOneD 35271 Specdb::NmrOneD 35272 Specdb::NmrOneD 35273 Specdb::NmrOneD 35274 Specdb::NmrOneD 35275 Specdb::NmrOneD 35276 Specdb::NmrOneD 35277 Specdb::NmrOneD 35278 Specdb::NmrOneD 35279 Specdb::NmrOneD 35280 Specdb::NmrOneD 35281 Specdb::CMs 3157 Specdb::CMs 30781 Specdb::CMs 38680 Specdb::CMs 99831 Specdb::CMs 147238 Prostate Tissue Wishart DS, Feunang YD, Marcu A, Guo AC, Liang K, Vazquez-Fresno R, Sajed T, Johnson D, Li C, Karu N, Sayeeda Z, Lo E, Assempour N, Berjanskii M, Singhal S, Arndt D, Liang Y, Badran H, Grant J, Serra-Cayuela A, Liu Y, Mandal R, Neveu V, Pon A, Knox C, Wilson M, Manach C, Scalbert A: HMDB 4.0: the human metabolome database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D608-D617. doi: 10.1093/nar/gkx1089. 29140435 FDB023276 389526 C05345 440641 16084 C00019548 Fructose_6-phosphate BMDBP00912 Hexokinase-1 P27595 HK1 Enzyme BMDBP01246 Glucose-6-phosphate isomerase Q3ZBD7 GPI Enzyme