1.0 2016-09-30 23:09:42 UTC 2020-05-21 16:29:06 UTC BMDB0004527 BMDB04527 1D-Myo-inositol 1,4,5,6-tetrakisphosphate 1D-Myo-1d-myo-inositol 1,4,5,6-tetrakisphosphate, also known as ins(1,4,5,6)P3, belongs to the class of organic compounds known as inositol phosphates. Inositol phosphates are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety. 1D-Myo-1d-myo-inositol 1,4,5,6-tetrakisphosphate is possibly soluble (in water) and an extremely strong acidic compound (based on its pKa). 1D-Myo-1d-myo-inositol 1,4,5,6-tetrakisphosphate exists in all eukaryotes, ranging from yeast to humans. 1D-Myo-1d-myo-inositol 1,4,5,6-tetrakisphosphate participates in a number of enzymatic reactions, within cattle. In particular, 1D-Myo-1d-myo-inositol 1,4,5,6-tetrakisphosphate can be converted into inositol 1,3,4,5,6-pentakisphosphate through the action of the enzyme inositol polyphosphate multikinase. Furthermore, 1D-Myo-1d-myo-inositol 1,4,5,6-tetrakisphosphate can be biosynthesized from inositol 1,4,5-trisphosphate; which is mediated by the enzyme inositol polyphosphate multikinase. Furthermore, 1D-Myo-1d-myo-inositol 1,4,5,6-tetrakisphosphate can be biosynthesized from inositol 1,4,5-trisphosphate through its interaction with the enzyme inositol polyphosphate multikinase. Finally, 1D-Myo-1d-myo-inositol 1,4,5,6-tetrakisphosphate can be converted into inositol 1,3,4,5,6-pentakisphosphate; which is mediated by the enzyme inositol polyphosphate multikinase. In cattle, 111d-myo-1d-myo-inositol 1,4,5,6-tetrakisphosphate is involved in a couple of metabolic pathways, which include the inositol phosphate metabolism pathway and the inositol metabolism pathway. Inositol 1,4,5,6-tetrakisphosphate Inositol 1,4,5,6-tetrakisphosphoric acid D-Myo-inositol 1,4,5,6-tetrakisphosphoric acid D-myo-Inositol 1,4,5,6-tetrakisphosphate 1D-myo-Inositol 1,4,5,6-tetrakisphosphoric acid Ins(1,4,5,6)P3 1D-myo-Inositol 1,4,5,6-tetrakisphosphate D-myo-Inositol 1,4,5,6-tetraphosphate Inositol 1,4,5,6-tetrakis(phosphate) Inositol 1,4,5,6-tetraphosphate Ins(1,4,5,6)P4 L-myo-Inositol 3,4,5,6-tetrakisphosphate C6H16O18P4 500.0755 499.928709756 {[(1S,2R,3S,4R,5R,6S)-3,4-dihydroxy-2,5,6-tris(phosphonooxy)cyclohexyl]oxy}phosphonic acid [(1S,2R,3S,4R,5R,6S)-3,4-dihydroxy-2,5,6-tris(phosphonooxy)cyclohexyl]oxyphosphonic acid 121010-58-0 O[C@H]1[C@@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O InChI=1S/C6H16O18P4/c7-1-2(8)4(22-26(12,13)14)6(24-28(18,19)20)5(23-27(15,16)17)3(1)21-25(9,10)11/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20)/t1-,2+,3-,4-,5+,6+/m1/s1 MRVYFOANPDTYBY-YORTWTKJSA-N belongs to the class of organic compounds known as inositol phosphates. Inositol phosphates are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety. Organic compounds Organic oxygen compounds Organooxygen compounds Alcohols and polyols Inositol phosphates 1,2-diols Cyclohexanols Hydrocarbon derivatives Monoalkyl phosphates Organic oxides 1,2-diol Aliphatic homomonocyclic compound Alkyl phosphate Cyclohexanol Hydrocarbon derivative Inositol phosphate Monoalkyl phosphate Organic oxide Organic phosphoric acid derivative Phosphoric acid ester Secondary alcohol Aliphatic homomonocyclic compounds myo-inositol tetrakisphosphate Solid logp -7.268 logp -0.45 ALOGPS logs -1.64 ALOGPS logp -4.3 ChemAxon pka_strongest_acidic 0.24 ChemAxon iupac {[(1S,2R,3S,4R,5R,6S)-3,4-dihydroxy-2,5,6-tris(phosphonooxy)cyclohexyl]oxy}phosphonic acid ChemAxon average_mass 500.0755 ChemAxon mono_mass 499.928709756 ChemAxon smiles O[C@H]1[C@@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O ChemAxon formula C6H16O18P4 ChemAxon inchi InChI=1S/C6H16O18P4/c7-1-2(8)4(22-26(12,13)14)6(24-28(18,19)20)5(23-27(15,16)17)3(1)21-25(9,10)11/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20)/t1-,2+,3-,4-,5+,6+/m1/s1 ChemAxon inchikey MRVYFOANPDTYBY-YORTWTKJSA-N ChemAxon polar_surface_area 307.5 ChemAxon refractivity 79.27 ChemAxon polarizability 34.03 ChemAxon rotatable_bond_count 8 ChemAxon acceptor_count 14 ChemAxon donor_count 10 ChemAxon physiological_charge -8 ChemAxon formal_charge 0 ChemAxon number_of_rings 1 ChemAxon bioavailability 0 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Inositol Metabolism SMP0087242 Inositol Phosphate Metabolism SMP0087256 Specdb::CMs 2395 Specdb::CMs 38765 Specdb::CMs 166582 Specdb::MsMs 178065 Specdb::MsMs 178066 Specdb::MsMs 178067 Specdb::MsMs 180378 Specdb::MsMs 180379 Specdb::MsMs 180380 Specdb::MsMs 2696592 Specdb::MsMs 2696593 Specdb::MsMs 2696594 Specdb::MsMs 2982866 Specdb::MsMs 2982867 Specdb::MsMs 2982868 Specdb::NmrOneD 149880 Specdb::NmrOneD 149881 Specdb::NmrOneD 149882 Specdb::NmrOneD 149883 Specdb::NmrOneD 149884 Specdb::NmrOneD 149885 Specdb::NmrOneD 149886 Specdb::NmrOneD 149887 Specdb::NmrOneD 149888 Specdb::NmrOneD 149889 Specdb::NmrOneD 149890 Specdb::NmrOneD 149891 Specdb::NmrOneD 149892 Specdb::NmrOneD 149893 Specdb::NmrOneD 149894 Specdb::NmrOneD 149895 Specdb::NmrOneD 149896 Specdb::NmrOneD 149897 Specdb::NmrOneD 149898 Specdb::NmrOneD 149899 391520 FDB023378 443266 C11555 16067 INOSITOL-1456-TETRAKISPHOSPHATE 2264980 BMDBP02946 Kinase F1N1W2 IPMK Enzyme BMDBP02948 Multiple inositol polyphosphate histidine phosphatase, 1 Q2TBT6 MINPP1 Enzyme