1.0 2016-09-30 23:09:56 UTC 2020-04-22 15:13:56 UTC BMDB0004631 BMDB04631 Formebolone (11a,17b)-11,17-Dihydroxy-17-methyl-3-oxo-androsta-1,4-diene-2-carboxaldehyde 11a,17b-Dihydroxy-17-methyl-3-oxo-androsta-1,4-diene-2-carboxaldehyde 11a,17b-Dihydroxy-17-methyl-3-oxoandrosta-1,4-diene-2-carboxaldehyde 2-Formyl-11a-hydroxy-D1-methyltestosterone 2-Formyl-17a-methylandrosta-1,4-dien-11a,17b-diol-3-one 2-Formyl-17a-methylandrosta-1,4-diene-11a,17b-dihydroxy-3-one 2-Formyl-17a-methylandrosta-1,4-diene-11a,17b-diol-3-one Esiclene Formyldienolone 2-Formyl-17 alpha-methylandrosta-1,4-diene-11 alpha,17 beta-diol-3-one Formyldienolone, (11 beta,17beta)-isomer Formildienolone Formebolone C21H28O4 344.4446 344.198759384 (1S,2R,10S,11S,14S,15S,17R)-14,17-dihydroxy-2,14,15-trimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-diene-4-carbaldehyde formebolone 2454-11-7 [H][C@@]12CC[C@](C)(O)[C@@]1(C)C[C@@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C(C=O)=C[C@]12C InChI=1S/C21H28O4/c1-19-9-12(11-22)16(23)8-13(19)4-5-14-15-6-7-21(3,25)20(15,2)10-17(24)18(14)19/h8-9,11,14-15,17-18,24-25H,4-7,10H2,1-3H3/t14-,15-,17+,18+,19-,20-,21-/m0/s1 AMVODTGMYSRMNP-GNIMZFFESA-N belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Androstane steroids Androgens and derivatives 11-alpha-hydroxysteroids 17-hydroxysteroids 3-oxo delta-1,4-steroids Aldehydes Cyclic alcohols and derivatives Cyclic ketones Delta-1,4-steroids Hydrocarbon derivatives Organic oxides Secondary alcohols Tertiary alcohols 11-alpha-hydroxysteroid 11-hydroxysteroid 17-hydroxysteroid 3-oxo-delta-1,4-steroid 3-oxosteroid Alcohol Aldehyde Aliphatic homopolycyclic compound Androgen-skeleton Carbonyl group Cyclic alcohol Cyclic ketone Delta-1,4-steroid Hydrocarbon derivative Hydroxysteroid Ketone Organic oxide Organic oxygen compound Organooxygen compound Oxosteroid Secondary alcohol Tertiary alcohol Aliphatic homopolycyclic compounds Solid melting_point 209 - 212 °C logp 2.59 ALOGPS logs -3.76 ALOGPS logp 1.76 ChemAxon pka_strongest_acidic 14.39 ChemAxon pka_strongest_basic -2.9 ChemAxon iupac (1S,2R,10S,11S,14S,15S,17R)-14,17-dihydroxy-2,14,15-trimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-diene-4-carbaldehyde ChemAxon average_mass 344.4446 ChemAxon mono_mass 344.198759384 ChemAxon smiles [H][C@@]12CC[C@](C)(O)[C@@]1(C)C[C@@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C(C=O)=C[C@]12C ChemAxon formula C21H28O4 ChemAxon inchi InChI=1S/C21H28O4/c1-19-9-12(11-22)16(23)8-13(19)4-5-14-15-6-7-21(3,25)20(15,2)10-17(24)18(14)19/h8-9,11,14-15,17-18,24-25H,4-7,10H2,1-3H3/t14-,15-,17+,18+,19-,20-,21-/m0/s1 ChemAxon inchikey AMVODTGMYSRMNP-GNIMZFFESA-N ChemAxon polar_surface_area 74.6 ChemAxon refractivity 96.9 ChemAxon polarizability 38.13 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon number_of_rings 4 ChemAxon bioavailability 1 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Specdb::CMs 16298 Specdb::CMs 38775 Specdb::CMs 172152 Specdb::MsMs 255882 Specdb::MsMs 255883 Specdb::MsMs 255884 Specdb::MsMs 275823 Specdb::MsMs 275824 Specdb::MsMs 275825 Specdb::MsMs 2467193 Specdb::MsMs 2467194 Specdb::MsMs 2467195 Specdb::MsMs 2498540 Specdb::MsMs 2498541 Specdb::MsMs 2498542 FDB023388 DB01569 17150 16234 Formebolone Canonica, Luigi; Jommi, Giancarlo; Pelizzoni, Francesca; Scolastico, Carlo. 1,11-Oxido steroids. I. 1a,11a-Oxidoandrostanes. Gazzetta Chimica Italiana (1965), 95(3), 138-50.