1.0 2016-09-30 23:21:34 UTC 2020-05-19 22:01:06 UTC BMDB0006330 BMDB06330 D-Mannose 1-phosphate D-D-d-mannose 1-phosphate, also known as d-mannose 1-phosphate, belongs to the class of organic compounds known as monosaccharide phosphates. These are monosaccharides comprising a phosphated group linked to the carbohydrate unit. D-D-d-mannose 1-phosphate is possibly soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). D-D-d-mannose 1-phosphate exists in all living species, ranging from bacteria to humans. D-D-d-mannose 1-phosphate participates in a number of enzymatic reactions, within cattle. In particular, D-D-d-mannose 1-phosphate can be converted into mannose 6-phosphate through its interaction with the enzyme phosphomannomutase 1. In addition, D-D-d-mannose 1-phosphate can be converted into guanosine diphosphate mannose through its interaction with the enzyme d-mannose 1-phosphatehosphate guanyltransferase beta. In cattle, D-d-mannose 1-phosphate is involved in the metabolic pathway called the fructose and mannose degradation pathway. 1-O-Phosphono-alpha-D-mannopyranose alpha-D-Mannose 1-phosphate 1-O-Phosphono-a-D-mannopyranose 1-O-Phosphono-α-D-mannopyranose a-D-Mannose 1-phosphate a-D-Mannose 1-phosphoric acid alpha-D-Mannose 1-phosphoric acid Α-D-mannose 1-phosphate Α-D-mannose 1-phosphoric acid D-Mannose 1-phosphoric acid Mannose phosphate Mannosyl phosphate alpha-D-Mannopyranosyl phosphate Α-D-mannopyranosyl phosphate D-Mannose 1-phosphate C6H13O9P 260.1358 260.029718526 {[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acid α-D-mannose 1-phosphate 15978-07-1 OC[C@H]1O[C@H](OP(O)(O)=O)[C@@H](O)[C@@H](O)[C@@H]1O InChI=1S/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5+,6-/m1/s1 HXXFSFRBOHSIMQ-RWOPYEJCSA-N belongs to the class of organic compounds known as monosaccharide phosphates. These are monosaccharides comprising a phosphated group linked to the carbohydrate unit. Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates Monosaccharide phosphates Hexoses Hydrocarbon derivatives Monoalkyl phosphates Organic oxides Oxacyclic compounds Oxanes Polyols Primary alcohols Secondary alcohols Alcohol Aliphatic heteromonocyclic compound Alkyl phosphate Hexose monosaccharide Hydrocarbon derivative Monoalkyl phosphate Monosaccharide phosphate Organic oxide Organic phosphoric acid derivative Organoheterocyclic compound Oxacycle Oxane Phosphoric acid ester Polyol Primary alcohol Secondary alcohol Aliphatic heteromonocyclic compounds D-mannose 1-phosphate alpha-D-hexose 1-phosphate Solid logp -2.00 ALOGPS logs -0.91 ALOGPS logp -3.1 ChemAxon pka_strongest_acidic 1.16 ChemAxon pka_strongest_basic -3 ChemAxon iupac {[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acid ChemAxon average_mass 260.1358 ChemAxon mono_mass 260.029718526 ChemAxon smiles OC[C@H]1O[C@H](OP(O)(O)=O)[C@@H](O)[C@@H](O)[C@@H]1O ChemAxon formula C6H13O9P ChemAxon inchi InChI=1S/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5+,6-/m1/s1 ChemAxon inchikey HXXFSFRBOHSIMQ-RWOPYEJCSA-N ChemAxon polar_surface_area 156.91 ChemAxon refractivity 46.8 ChemAxon polarizability 20.79 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 8 ChemAxon donor_count 6 ChemAxon physiological_charge -2 ChemAxon formal_charge 0 ChemAxon number_of_rings 1 ChemAxon bioavailability 1 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Fructose and Mannose Degradation SMP0087197 Specdb::NmrOneD 150140 Specdb::NmrOneD 150141 Specdb::NmrOneD 150142 Specdb::NmrOneD 150143 Specdb::NmrOneD 150144 Specdb::NmrOneD 150145 Specdb::NmrOneD 150146 Specdb::NmrOneD 150147 Specdb::NmrOneD 150148 Specdb::NmrOneD 150149 Specdb::NmrOneD 150150 Specdb::NmrOneD 150151 Specdb::NmrOneD 150152 Specdb::NmrOneD 150153 Specdb::NmrOneD 150154 Specdb::NmrOneD 150155 Specdb::NmrOneD 150156 Specdb::NmrOneD 150157 Specdb::NmrOneD 150158 Specdb::NmrOneD 150159 Specdb::CMs 2553 Specdb::CMs 102810 Specdb::CMs 102811 Specdb::CMs 151807 Specdb::MsMs 178431 Specdb::MsMs 178432 Specdb::MsMs 178433 Specdb::MsMs 180750 Specdb::MsMs 180751 Specdb::MsMs 180752 Specdb::MsMs 1471095 Specdb::MsMs 1471096 Specdb::MsMs 1471097 Specdb::MsMs 1471098 Specdb::MsMs 1471099 Specdb::MsMs 1471126 Specdb::MsMs 1471621 Specdb::MsMs 1471622 Specdb::MsMs 1471623 Specdb::MsMs 1471624 Specdb::MsMs 1471625 Specdb::MsMs 1471626 Specdb::MsMs 1471627 Specdb::MsMs 1471628 Specdb::MsMs 1471629 Specdb::MsMs 1471630 Specdb::MsMs 1471631 Specdb::MsMs 1471632 Specdb::MsMs 1471633 Placenta Wishart DS, Feunang YD, Marcu A, Guo AC, Liang K, Vazquez-Fresno R, Sajed T, Johnson D, Li C, Karu N, Sayeeda Z, Lo E, Assempour N, Berjanskii M, Singhal S, Arndt D, Liang Y, Badran H, Grant J, Serra-Cayuela A, Liu Y, Mandal R, Neveu V, Pon A, Knox C, Wilson M, Manach C, Scalbert A: HMDB 4.0: the human metabolome database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D608-D617. doi: 10.1093/nar/gkx1089. 29140435 FDB031268 C00636 388412 439279 18205 C00007389 MANNOSE-1P Mannose_1-phosphate BMDBP01119 Mannose-1-phosphate guanyltransferase beta Q2YDJ9 GMPPB Enzyme BMDBP01128 Phosphomannomutase 2 Q3SZJ9 PMM2 Enzyme