1.0 2016-10-03 18:14:13 UTC 2020-04-22 15:43:08 UTC BMDB0011180 BMDB11180 L-prolyl-L-proline L-Prolyl-L-proline , also known as D-pro-L-pro, belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. L-Prolyl-L-proline is possibly soluble (in water) and a very strong basic compound (based on its pKa). Prolylproline D-pro-L-Pro Prolyl-proline C10H16N2O3 212.2456 212.116092388 1-(pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid 1-(pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid OC(=O)C1CCCN1C(=O)C1CCCN1 InChI=1S/C10H16N2O3/c13-9(7-3-1-5-11-7)12-6-2-4-8(12)10(14)15/h7-8,11H,1-6H2,(H,14,15) RWCOTTLHDJWHRS-UHFFFAOYSA-N belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Dipeptides Alpha amino acid amides Amino acids Azacyclic compounds Carbonyl compounds Carboxylic acids Dialkylamines Hydrocarbon derivatives Monocarboxylic acids and derivatives N-acyl-alpha amino acids N-acylpyrrolidines Organic oxides Organopnictogen compounds Proline and derivatives Pyrrolidine carboxylic acids Pyrrolidinecarboxamides Tertiary carboxylic acid amides Aliphatic heteromonocyclic compound Alpha-amino acid amide Alpha-amino acid or derivatives Alpha-dipeptide Amine Amino acid Amino acid or derivatives Azacycle Carbonyl group Carboxamide group Carboxylic acid Hydrocarbon derivative Monocarboxylic acid or derivatives N-acyl-alpha amino acid or derivatives N-acyl-alpha-amino acid N-acylpyrrolidine Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Proline or derivatives Pyrrolidine Pyrrolidine carboxylic acid Pyrrolidine carboxylic acid or derivatives Pyrrolidine-2-carboxamide Secondary aliphatic amine Secondary amine Tertiary carboxylic acid amide Aliphatic heteromonocyclic compounds Solid logp -2.34 ALOGPS logs -0.83 ALOGPS logp -2.8 ChemAxon pka_strongest_acidic 3.7 ChemAxon pka_strongest_basic 9.82 ChemAxon iupac 1-(pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid ChemAxon average_mass 212.2456 ChemAxon mono_mass 212.116092388 ChemAxon smiles OC(=O)C1CCCN1C(=O)C1CCCN1 ChemAxon formula C10H16N2O3 ChemAxon inchi InChI=1S/C10H16N2O3/c13-9(7-3-1-5-11-7)12-6-2-4-8(12)10(14)15/h7-8,11H,1-6H2,(H,14,15) ChemAxon inchikey RWCOTTLHDJWHRS-UHFFFAOYSA-N ChemAxon polar_surface_area 69.64 ChemAxon refractivity 53.05 ChemAxon polarizability 21.88 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon number_of_rings 2 ChemAxon bioavailability 1 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon Specdb::CMs 19705 Specdb::CMs 39590 Specdb::MsMs 309838 Specdb::MsMs 309839 Specdb::MsMs 309840 Specdb::MsMs 354376 Specdb::MsMs 354377 Specdb::MsMs 354378 Milk Fermented milk, by capillary electrophoresis-TOFMS Hagi T, Kobayashi M, Nomura M: Metabolome analysis of milk fermented by gamma-aminobutyric acid-producing Lactococcus lactis. J Dairy Sci. 2016 Feb;99(2):994-1001. doi: 10.3168/jds.2015-9945. Epub 2015 Dec 10. 26686724 FDB027952 263469 Hagi T, Kobayashi M, Nomura M: Metabolome analysis of milk fermented by gamma-aminobutyric acid-producing Lactococcus lactis. J Dairy Sci. 2016 Feb;99(2):994-1001. doi: 10.3168/jds.2015-9945. Epub 2015 Dec 10. 26686724