Ear size

Phene ID

5257

Name

Ear size

Phene Name

N/A

OMIA ID

1579

Species ID

9913

Characterised

No

Characterised Year

N/A

Shen et al. (2023) investigated ear size in Bos taurus, Bos indicus and hybrids. "Results showed that the ear size of breeds followed the order: Bos indicus > hybrid (Yunling) and Chinese indicine (Wenshan and Dabieshan cattle) cattle > Bos taurus ..."

Shen et al. (2023) "The most significant locus (P = 1.30 × 10-8) was a missense mutation (T250I) on the seventh exon of integrin-binding sialoprotein (IBSP), which had an allele substitution effect of 23.46 cm2 for ear size. ... A allele frequency of IBSP was lowest in South Asian indicine cattle (0.10), and the frequency was 0.47 in Chinese indicine cattle. However, the A frequency of IBSP was near or equal to 1 in East Asian, European, and Eurasian taurine cattle ... .To further evaluate the functional impact of the variants, we aligned the mutant IBSP protein with its ortholog proteins in Bovidae ... and other diverse vertebrates ... . The comparison revealed that T250 was a conserved amino acid mutation and varied among all the other animals we examined except Bos taurus (T250I), lesser mouse-deer (T250S), and white-lipped deer (T250A). ... These three mutant species had small ears, and this finding was consistent with our present hypothesis."