| Identification |
|---|
| BMDB Protein ID
| BMDBP00084 |
| Secondary Accession Numbers
| None |
| Name
| Serine--tRNA ligase, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| SARS2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Translation, ribosomal structure and biogenesis |
| Specific Function
| Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec). |
| Pathways
|
- Aminoacyl-tRNA biosynthesis
- L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1
- Selenocysteinyl-tRNA(Sec) biosynthesis
|
| Reactions
|
| L-Serine + Adenosine triphosphate + L-Seryl-tRNA → Adenosine monophosphate + L-Seryl-tRNA(Ser) + Pyrophosphate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 18 |
| Locus
| Not Available |
| SNPs
| SARS2 |
| Gene Sequence
|
>1557 bp
ATGGCTGCGTCCATAGTGCGGCGCTTGGGTCCTCTAGTAGCTGGTCGGGGCCTGCGGCTT
CGAGGAGGCTGTGTCTGTAACCAGAGCTTCAAGAGAAGTTTCGCAACGGAGAGGCAGGAT
CGGAACCTCCTGTACGAACACGCGCGTGAGGGCTACAGCGCGCTCCCTCTGCTGGATATG
GAATCACTGTGCGCATACCCGGAAGATGCCGCGCGCGCGCTGGATCTCCGCAAGGGGGAG
TTGCGGTCTAAGGATCTGCCCGGCATCATCTCAACATGGCAGGAGCTGAGGCAGCTGCGG
GAACAGATCCGGAGCCTGGAGGAGGAGAAGGAGGCTGTGACAGAGGCAGTGCGGGCCCTG
GTGGTAAACCAGGACAACAGTCAAGTGCAGCAGGACCCCCAATATCAGAGTCTGCGGGCA
CGTGGCCGGGAGATCCGGAAGCAGCTCACACTCCTCTACCCCAAGGAGGCCCAGCTCGAA
GAGCAGTTCTACCTGCGGGCACTGAGGCTGCCCAACCAGACCCACCCAGACGTGCCTGTC
GGGGACGAAAGCCAGGCCCGCGTGCTCCATGTGGTTGGAGACAAGCCAGCTTTCTCCTTC
CAACCCCGGGGCCACCTGGAAATAGCCGAGAAACTCGACATCATCCGTCAGAAGCGCCTG
TCCCATGTGTCTGGCCACCGCTCCTATTACCTGCGCGGGGCTGGGGCCCTCCTGCAGCAC
GGCCTGGTCAACTTCACACTCAACAAGCTCATCCACCGGGGCTTCACCCCCATGACGGTG
CCAGACCTTCTCCGAGGAGTTGTGTTTGAAGGCTGTGGGATGACACCAAATGCCAAACCA
TCCCAAATTTACAACATCGACCCCTCCCGCTTTGAAGACCTCAATCTGGCCGGGACAGCG
GAGGTAGGACTTGCAGGCTACTTCATGGACCACTCCGTGGCCTTCAGGGACCTGCCAATC
AGGATGGTTTGTTCCAGTACCTGCTACCGGGCGGAAACAGACACGGGGAAGGAGCCGTGG
GGGCTGTATCGAGTACACCACTTCACCAAGGTGGAGATGTTTGGGGTGACAGGCCCCGGG
CTGGAGCAGAGCTCAGAGCTGCTGGAGGAGTTCCTGTCCCTTCAGATGGAGATCTTGACA
GAGCTGGGCTTGCACTTCCGAGTCCTGGACATGCCCACACAGGAGCTGGGCCTGCCCGCC
TACCGCAAGTTCGACATTGAGGCCTGGATGCCAGGGCGAGGCCGGTTCGGTGAGGTCACC
AGTGCTTCCAACTGCACGGACTTCCAGAGCCGCCGTTTACACATCATGTTCCAGACCGAG
GCCGGGGAGCTGCAGTTCGCACACACGGTGAATGCCACGGGCTGTGCTGTCCCTCGTCTC
CTCATCGCCCTCCTGGAGAGCTATCAGCAGAAGGACGGCTCAGTGCTCGTGCCCCCTGCC
CTCCAGCCCTACCTCGGCACCGATCGGATCACCACCCCCACCCACGTGCCTCTCCAGTAC
ATCGGCCCCAACCAGCCCCAGAAGCCCAGGCTCCCGGGCCAGCCTGCCTCGAGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 518 |
| Molecular Weight
| 58296.0 |
| Theoretical pI
| 7.62 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Seryl-tRNA synthetase, mitochondrial
MAASIVRRLGPLVAGRGLRLRGGCVCNQSFKRSFATERQDRNLLYEHAREGYSALPLLDM
ESLCAYPEDAARALDLRKGELRSKDLPGIISTWQELRQLREQIRSLEEEKEAVTEAVRAL
VVNQDNSQVQQDPQYQSLRARGREIRKQLTLLYPKEAQLEEQFYLRALRLPNQTHPDVPV
GDESQARVLHVVGDKPAFSFQPRGHLEIAEKLDIIRQKRLSHVSGHRSYYLRGAGALLQH
GLVNFTLNKLIHRGFTPMTVPDLLRGVVFEGCGMTPNAKPSQIYNIDPSRFEDLNLAGTA
EVGLAGYFMDHSVAFRDLPIRMVCSSTCYRAETDTGKEPWGLYRVHHFTKVEMFGVTGPG
LEQSSELLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVT
SASNCTDFQSRRLHIMFQTEAGELQFAHTVNATGCAVPRLLIALLESYQQKDGSVLVPPA
LQPYLGTDRITTPTHVPLQYIGPNQPQKPRLPGQPASS
|
| External Links |
|---|
| GenBank ID Protein
| BAA99556.1 |
| UniProtKB/Swiss-Prot ID
| Q9N0F3 |
| UniProtKB/Swiss-Prot Entry Name
| SYSM_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| AB029947 |
| GeneCard ID
| SARS2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
