| Identification |
|---|
| BMDB Protein ID
| BMDBP00187 |
| Secondary Accession Numbers
| None |
| Name
| Dual specificity protein phosphatase 18 |
| Synonyms
|
Not Available
|
| Gene Name
| DUSP18 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Signal transduction mechanisms |
| Specific Function
| Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 17 |
| Locus
| Not Available |
| SNPs
| DUSP18 |
| Gene Sequence
|
>567 bp
ATGACAGCATCCCCGTGTGCCTTCCCAGTTCAGTTCCGGCAGCCCTCGGTCAGTGGCCTC
TCACAGATCACCAGTAGCCTGTATATCAGCAGCGGGGTGGCCGCCAACAACAGGCTCATG
CTCTCCAGCAACCGCATCAGCACGGTCATCAATGTCTCAGTGGAGGTGGTGAACGCCTTG
TACGAGGACATTCACTATGTGCAGGTGCCCGTGGCCGACACGCCCACCTCGCGGCTCTGT
GACTTCTTCGACCCCATCGCAGACCACATCCACAGCGTGGAGATGAAGCAGGGCCGCACC
CTGCTGCACTGCGCCGCCGGCGTCAGCCGCTCGGCTGCCCTCTGCCTCGCCTATCTCATG
AAGTACCACGCCATGTCCCTGCTGGACGCCCACACGTGGACCAAGTCCTGCCGGCCCATC
ATCCGGCCCAACAACGGCTTTTGGGAGCAGCTCATCCACTATGAGTTCCAGCTATTTGGC
AGGAATACCGTGCACATGGTCAGCTCCCCCGTGGGCATGATCCCTGACATCTACGAGAAG
GAGGTCCGTCAGATGATTCCACTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 188 |
| Molecular Weight
| 21028.0 |
| Theoretical pI
| 7.57 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Dual specificity protein phosphatase 18
MTASPCAFPVQFRQPSVSGLSQITSSLYISSGVAANNRLMLSSNRISTVINVSVEVVNAL
YEDIHYVQVPVADTPTSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM
KYHAMSLLDAHTWTKSCRPIIRPNNGFWEQLIHYEFQLFGRNTVHMVSSPVGMIPDIYEK
EVRQMIPL
|
| External Links |
|---|
| GenBank ID Protein
| AAX31357.1 |
| UniProtKB/Swiss-Prot ID
| Q5BIP9 |
| UniProtKB/Swiss-Prot Entry Name
| DUS18_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT021175 |
| GeneCard ID
| DUSP18 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
