| Identification |
|---|
| BMDB Protein ID
| BMDBP00189 |
| Secondary Accession Numbers
| None |
| Name
| ATP synthase subunit beta, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| ATP5F1B |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| ATP5F1B |
| Gene Sequence
|
>1587 bp
ATGTTGGGACTTGTGGGTCGTGTGGTTGCTGCCTCGGCCTCCGGGGCCTTGCGGGGACTC
AGCCCTTCAGCGCCGCTACCGCAAGCCCAGCTTTTACTGCGGGCCGCTCCTGCAGCGCTC
CAGCCTGCCAGAGACTATGCCGCTCAAGCATCTCCATCGCCAAAGGCCGGCGCCACCACT
GGGCGCATCGTGGCGGTCATTGGTGCAGTGGTGGACGTCCAGTTTGATGAGGGACTGCCT
CCCATCCTAAATGCCCTGGAGGTGCAAGGCAGGGAGACCAGGCTGGTTTTGGAGGTGGCC
CAGCATTTGGGTGAGAGCACAGTAAGGACCATTGCTATGGATGGTACAGAAGGCTTGGTT
AGAGGTCAGAAAGTCCTGGATTCTGGTGCACCAATCAGAATTCCTGTTGGCCCTGAGACC
TTGGGTAGAATCATGAACGTCATTGGAGAACCTATTGATGAGAGGGGTCCCATCAAAACC
AAGCAATTTGCTGCTATTCATGCTGAGGCTCCTGAATTCGTGGAGATGAGTGTTGAACAA
GAAATTCTGGTTACTGGTATTAAGGTTGTAGATCTGCTGGCTCCATATGCCAAGGGTGGC
AAAATTGGGCTTTTTGGTGGTGCTGGAGTCGGCAAGACAGTACTGATCATGGAGTTAATC
AACAATGTTGCCAAAGCCCATGGTGGTTACTCTGTGTTTGCTGGTGTTGGTGAAAGGACC
CGTGAGGGCAATGACTTATACCATGAAATGATTGAGTCTGGTGTTATCAACTTAAAAGAT
GCTACCTCTAAGGTAGCGCTGGTGTACGGTCAAATGAATGAACCACCTGGTGCTCGGGCC
CGGGTTGCTCTGACTGGGCTGACTGTAGCTGAGTACTTCAGAGACCAAGAAGGTCAAGAT
GTGTTGCTGTTTATTGATAACATCTTTCGCTTCACCCAGGCTGGCTCAGAGGTGTCTGCT
TTATTGGGCAGAATCCCTTCTGCTGTGGGTTATCAGCCTACCCTGGCCACTGACATGGGT
ACCATGCAGGAAAGAATCACCACCACCAAAAAGGGATCTATCACCTCTGTACAGGCTATC
TATGTGCCTGCTGATGACTTGACGGATCCTGCCCCGGCCACTACCTTTGCCCATTTGGAT
GCTACCACTGTGTTGTCCCGTGCTATTGCTGAGCTGGGCATCTATCCAGCTGTGGATCCT
TTGGACTCCACGTCTCGCATCATGGATCCCAACATTGTTGGCAGTGAGCATTATGATGTT
GCCCGTGGGGTGCAAAAGATTCTGCAGGACTACAAATCCCTCCAGGACATCATTGCTATC
CTGGGTATGGATGAACTTTCTGAAGAAGATAAGTTAACTGTGTCTCGTGCACGGAAAATC
CAGCGTTTCTTGTCTCAGCCATTCCAGGTGGCTGAGGTCTTTACTGGTCATTTGGGGAAG
CTGGTACCCCTCAAGGAGACCATCAAAGGATTCCAGCAGATTTTGGCAGGTGAATATGAC
CATCTCCCAGAACAGGCCTTCTATATGGTGGGACCCATTGAAGAAGCTGTGGCAAAAGCT
GATAAGTTGGCTGAAGAGCACTCATGA
|
| Protein Properties |
|---|
| Number of Residues
| 528 |
| Molecular Weight
| 56284.0 |
| Theoretical pI
| 4.92 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>ATP synthase subunit beta, mitochondrial
MLGLVGRVVAASASGALRGLSPSAPLPQAQLLLRAAPAALQPARDYAAQASPSPKAGATT
GRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLV
RGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMSVEQ
EILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERT
REGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQD
VLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAI
YVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDV
ARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHLGK
LVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEHS
|
| External Links |
|---|
| GenBank ID Protein
| AAA30395.1 |
| UniProtKB/Swiss-Prot ID
| P00829 |
| UniProtKB/Swiss-Prot Entry Name
| ATPB_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| M20929 |
| GeneCard ID
| ATP5F1B |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
