| Identification |
|---|
| BMDB Protein ID
| BMDBP00214 |
| Secondary Accession Numbers
| None |
| Name
| Pyridoxine-5'-phosphate oxidase |
| Synonyms
|
Not Available
|
| Gene Name
| PNPO |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Coenzyme transport and metabolism |
| Specific Function
| Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). |
| Pathways
|
- Cofactor metabolism
- Pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.
- Pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1
- Pyridoxal 5'-phosphate salvage
- Vitamin B6 Metabolism
|
| Reactions
|
| Pyridoxamine + Water + Oxygen → Pyridoxal + Ammonia + Hydrogen peroxide |
details
|
| Pyridoxine + Oxygen → Pyridoxal + Hydrogen peroxide |
details
|
| Pyridoxamine 5'-phosphate + Water + Oxygen → Pyridoxal 5'-phosphate + Ammonia + Hydrogen peroxide |
details
|
| Pyridoxine 5'-phosphate + Oxygen → Pyridoxal 5'-phosphate + Hydrogen peroxide |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| Not Available |
| SNPs
| PNPO |
| Gene Sequence
|
>786 bp
ATGATATTCTGGCTGCGGAGCGTCATCGTGACGTTTGGGCGACCTGCCGAGTGGCCCCGC
TGCCTCCGCCACCTCTGCAGCCGCGGTGCTGCCATGGACCTGGGACCGATGCGCAAGACT
TACCGCGGGGACCCAGAGGCATTTGAGGAGACTCATCTGACCTCCCTGGACCCTGTGAAG
CAGTTTGCTGCCTGGTTCGAGGAGGCTGTTCAGTGTCCTGACATAATGGAAGCCAACGCC
ATGTGTCTGGCTACGTGTACAAGAGATGGGAAACCGTCTGCCCGCATGGTGCTGTTGAAG
GGCTTTGGCAAGGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAGGGAAAAGAG
CTGGACTCGAATCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCCCTGCACCGTCAGGTG
CGTGTGGAGGGGCCCGTGAAGAAGCTGCCTGAGGAGGAGGCTGAATGCTACTTCCACTCC
CGCCCCAAAAGCAGCCAGATTGGGGCTGTGGTCAGTCACCAGAGTTCCGTGATCCCGGAT
CGGGAGTATCTGAGAAAGAAAAATAAGGAACTGGAGCAACTCTACCAGGAACAAGAGGTG
CCAAAGCCAAAATACTGGGGTGGCTACATCCTGTACCCACAGGTGATGGAGTTCTGGCAG
GGCCAAACCAACCGCCTGCACGACCGGATCGTCTTTCGACGAGGCCTACTAACCGGAGAC
TCCCCTCTGGGGCCCATGACCCACCGAGGCGAGGAAGACTGGGTCTATGAGAGACTTGCG
CCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 261 |
| Molecular Weight
| 30366.0 |
| Theoretical pI
| 8.13 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Pyridoxine-5'-phosphate oxidase
MIFWLRSVIVTFGRPAEWPRCLRHLCSRGAAMDLGPMRKTYRGDPEAFEETHLTSLDPVK
QFAAWFEEAVQCPDIMEANAMCLATCTRDGKPSARMVLLKGFGKDGFRFFTNFESRKGKE
LDSNPFASLVFYWEPLHRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPD
REYLRKKNKELEQLYQEQEVPKPKYWGGYILYPQVMEFWQGQTNRLHDRIVFRRGLLTGD
SPLGPMTHRGEEDWVYERLAP
|
| External Links |
|---|
| GenBank ID Protein
| AAX08934.1 |
| UniProtKB/Swiss-Prot ID
| Q5E9K3 |
| UniProtKB/Swiss-Prot Entry Name
| PNPO_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT020917 |
| GeneCard ID
| PNPO |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
