1.0 2018-05-07 22:21:31 UTC 2020-05-20 21:10:21 UTC BMDBP00251 Enzyme ZDHHC16 Involved in acyltransferase activity Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6 (By similarity). Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN phosphorylation and homooligomerization (By similarity). Also required for eye development (By similarity). Palmitoylates ZDHHC6, affecting the quaternary assembly of ZDHHC6, its localization, stability and function (By similarity). May play a role in DNA damage response (By similarity). May be involved in apoptosis regulation (By similarity). Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity). BMDB0001338 Palmityl-CoA 26 >1086 bp ATGCGGGGCCAGTGGAGCCTACTGCTGGGCCCTGCCCGCCTTTGCCTGCGCCTGCTTCTG CTCCTGGGCTACAGGCGCCGCTGCCCACCTCTGCTCCGCGGCCTGGTGCAGCGCTGGCGC TACGGCAAGGTCTGCCTGCGCTCCCTGCTCTACAACTCCTTCGGGGGCAGTGACACCGCC GTGGACGCTGCCTTTGAGCCTATCTACTGGCTGGTGGACAACGTGATCCGCTGGTGTGGG GTGGTGTTCGTGGTGCTGGTGATCGTGCTGACCAGCTCCATCGTGGCCATCGCCTACCTG TGTGTCCTGCCCCTCATCCTCCAAACCTACTCCGTGCCCCGGCTCTGCTGGCATTTCTTC TATAGTCACTGGAATCTGATTCTCATCGTCTTCCATTACTACCAGGCTATCACCACCCCA CCTGGATACCCACCCCAGGGCAGGAATGATATGACAACAGTCTCCATCTGTAAGAAGTGC ATTAACCCCAAGCCAGCCCGAACACACCACTGCAGCATCTGCAATAGGTGTGTGCTGAAG ATGGATCATCACTGCCCCTGGCTAAACAACTGTGTGGGCCACTATAACCATCGGTACTTC TTCTCTTTCTGCTTTTTCATGACCCTGGGCTGTGTCTACTGCAGCTATGGAAGCTGGGAC CTTTTCCGGGAGGCTTATGCTGCCATCGAGACTTACCATCAGACCCCACCACCCACCTTC TCCTTCCGAGAAAGAGTGACTCACAAGAGTCTTGTCTACCTCTGGTTCCTGTGCAGTTCT GTGGCACTTGCCCTGGGTGCCCTAACCATATGGCACGCTGTGCTCATCAGTCGAGGTGAG ACTAGCATCGAAAGGCACATCAACAAGAAGGAGCGCCAGCGGCTGCAGGCCAAGGGCAGA GTTTTTAGGAATCATTACAACTATGGTTGCTTGGACAACTGGAAGGTATTCCTGGGTGTG GACACAGGAAGGCACTGGCTTACTCGGGTGTTGTTACCTTCCAGTCACTTGCCCCATGGG AACGGAATGAGCTGGGATCCCCCGCCCTGGGTGACTGCTCACTCAGCCTCTGTGATGGCA GTGTGA 377 43614.0 9.68 80-100 117-137 199-219 267-287 None >Probable palmitoyltransferase ZDHHC16 MRGQWSLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTA VDAAFEPIYWLVDNVIRWCGVVFVVLVIVLTSSIVAIAYLCVLPLILQTYSVPRLCWHFF YSHWNLILIVFHYYQAITTPPGYPPQGRNDMTTVSICKKCINPKPARTHHCSICNRCVLK MDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIEKMKQLDKNKL QAVANQTYHQTPPPTFSFRERVTHKSLVYLWFLCSSVALALGALTIWHAVLISRGETSIE RHINKKERQRLQAKGRVFRNHYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMS WDPPPWVTAHSASVMAV AAX46555.1 Q58CU4 ZDH16_BOVIN BT021708 ZDHHC16