| Identification |
|---|
| BMDB Protein ID
| BMDBP00372 |
| Secondary Accession Numbers
| None |
| Name
| Diamine acetyltransferase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| SAT1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Transcription |
| Specific Function
| Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine (By similarity). |
| Pathways
|
- Amine and polyamine degradation
- N-acetylputrescine from putrescine: step 1/1
- Putrescine degradation
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| X |
| Locus
| Not Available |
| SNPs
| SAT1 |
| Gene Sequence
|
>516 bp
ATGGCTAAATTCGTGATCCGCCCGGCCACCGCTGCCGACTGCAGTGACATCCTGCGGCTG
ATCAAGGAATTGGCTAAATACGAATACATGGAAGAGCAAGTAATGTTAACTGAAAAAGAT
CTGCTGGAAGACGGTTTCGGAGAGCACCCCTTCTACCACTGCTTAGTTGCAGAAGTGCCC
AAGGAGCACCTGACTCCGGAAGGACACAGCATTGTTGGTTTTGCCATGTACTATTTTACC
TATGATCCATGGATCGGCAAACTGTTGTATCTTGAGGACTTCTTTGTGATGAGCGATTAT
AGAGGCTTTGGCATAGGCTCAGAAATTCTGAAGAAGCTAAGCCAGGTTGCAATGAAGTGT
CGCTGCAGCAGCATGCACTTCTTGGTGGCAGAGTGGAATGAACCATCTATCAACTTCTAC
AAAAGAAGAGGTGCCTCTGATCTATCCAGCGAAGAGGGATGGAGACTCTTCAAGATCGAC
AAGGAGTACTTGCTAAAAATGGCAGCAGAGGAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 171 |
| Molecular Weight
| 19925.0 |
| Theoretical pI
| 4.95 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Diamine acetyltransferase 1
MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVMLTEKDLLEDGFGEHPFYHCLVAEVP
KEHLTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKKLSQVAMKC
RCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMAAEE
|
| External Links |
|---|
| GenBank ID Protein
| AAI02305.1 |
| UniProtKB/Swiss-Prot ID
| Q3T0Q0 |
| UniProtKB/Swiss-Prot Entry Name
| SAT1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC102304 |
| GeneCard ID
| SAT1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
