Showing Protein Sepiapterin reductase (BMDBP00379)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 11 metabolites
Identification
BMDB Protein ID BMDBP00379
Secondary Accession Numbers
  • BMDBP03157
Name Sepiapterin reductase
Synonyms Not Available
Gene Name SPR
Protein Type Enzyme
Biological Properties
General Function Lipid transport and metabolism
Specific Function Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
Pathways Not Available
Reactions
Dyspropterin + NADP → NADPH + 1-hydroxy-2-Oxopropyl tetrahydropterin details
Sepiapterin + NADPH → 7,8-Dihydroneopterin + NADP details
6-Lactoyltetrahydropterin + NADP → Tetrahydrobiopterin + NADPH details
6-Lactoyltetrahydropterin + NAD → 1-hydroxy-2-Oxopropyl tetrahydropterin + NADH details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 11
Locus Not Available
SNPs SPR
Gene Sequence 
>804 bp
ATGGAGGGCAGCGTCGGCAAGGTGGGCGGCCTGGGGCGCACCTTATGCGTGCTGACTGGG
GCTTCCCGGGGCTTCGGACGGACGCTGGCCCAAGTCCTGGCCCCGCTGATGTCGCCTCGC
TCCGTGCTGGTCCTAAGCGCCCGCAATGACGAGGCCCTGCGGCAGCTGGAGACCGAGCTG
GGCGCCGAGTGGCCGGGTCTGCGTATCGTGCGGGTGCCCGCCGACCTGGGCGCCGAGACC
GGCTTGCAGCAACTGGTCGGTGCTCTGTGCGACCTCCCCAGGCCCGAGGGCCTGCAGCGA
GTGCTGCTCATCAACAATGCGGGCACTCTTGGAGATGTATCCAAACGTTGGGTGGACCTG
ACTGACCCAACTGAAGTGAACAACTACTGGACTCTGAACTTGACTTCCACGCTCTGCCTG
ACTTCCAGTATCCTGCAGGCCTTCCCGGACAGTCCTGGCCTCAGCAGGACTGTGGTTAAC
ATCTCGTCCATCTGTGCCCTGCAGCCCTTCAAGGGCTGGGGACTGTACTGTGCTGGGAAG
GCTGCCCGTAACATGATGTTCCAGGTCCTGGCGGCGGAGGAACCTAGCGTGAGGGTGCTG
AGCTATGGCCCAGGTCCCCTGGACACTGACATGCAGCAGTTAGCCCGGGAGACCTCTGTG
GACCCAGACTTGCGAAAAAGCCTGCAGGAGCTGAAGAGAAAGGGGCAACTTGTGGATTGC
AAGATATCAGCCCAGAAACTTCTGAGCTTGCTGCAAAATGACAAGTTCGAGTCTGGAGCC
CATATTGACTTCTACGATGAATAA
Protein Properties
Number of Residues 267
Molecular Weight 28939.0
Theoretical pI 5.15
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence 
>Sepiapterin reductase
MEGSVGKVGGLGRTLCVLTGASRGFGRTLAQVLAPLMSPRSVLVLSARNDEALRQLETEL
GAEWPGLRIVRVPADLGAETGLQQLVGALCDLPRPEGLQRVLLINNAGTLGDVSKRWVDL
TDPTEVNNYWTLNLTSTLCLTSSILQAFPDSPGLSRTVVNISSICALQPFKGWGLYCAGK
AARNMMFQVLAAEEPSVRVLSYGPGPLDTDMQQLARETSVDPDLRKSLQELKRKGELVDC
KISAQKLLSLLQNDKFESGAHIDFYDE
GenBank ID Protein ABI79460.1
UniProtKB/Swiss-Prot ID Q17QK8
UniProtKB/Swiss-Prot Entry Name SPRE_BOVIN
PDB IDs Not Available
GenBank Gene ID DQ978331
GeneCard ID SPR
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available