| Identification |
|---|
| BMDB Protein ID
| BMDBP00382 |
| Secondary Accession Numbers
| None |
| Name
| Polypeptide N-acetylgalactosaminyltransferase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| GALNT1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7. |
| Pathways
|
- Protein glycosylation
- Protein modification
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 24 |
| Locus
| Not Available |
| SNPs
| GALNT1 |
| Gene Sequence
|
>1680 bp
ATGAGAAAATTTGCATACTGCAAGGTGGTCCTAGCCACCTCCTTGATTTGGGTACTCTTG
GATATGTTCCTGCTGCTTTACTTCAGTGAATGCAACAAATGTGATGAAAAAAAAGAGAGA
GGACTTCCTGCTGGGGATGTTCTAGAGCCAGTACAAAAGCCTCATGAAGGTCCTGGAGAA
ATGGGGAAACCAGTCGTCATTCCTAAAGAGGATCAAGAAAAGATGAAAGAGATGTTTAAA
ATCAATCAGTTCAATTTAATGGCAAGTGAGATGATTGCACTCAACAGATCTCTACCAGAT
GTTAGATTAGAAGGGTGTAAAACAAAGGTGTATCCAGATAACCTTCCTACAACCAGTGTG
GTGATTGTTTTCCACAATGAGGCTTGGAGCACACTTCTGCGAACTGTCCATAGCGTCATT
AATCGCTCACCAAGGCACATGCTAGAAGAAATTGTTCTAGTAGATGATGCCAGTGAAAGA
GACTTTTTAAAAAGACCTCTAGAGAGTTACGTGAAAAAATTAAAAGTACCCGTTCACGTC
ATTCGAATGGAGCAGCGTTCTGGATTGATCAGAGCTAGGTTAAAAGGTGCTGCTGTGTCT
AAAGGCCAAGTGATCACCTTTTTAGACGCGCACTGTGAGTGCACAGTGGGGTGGCTGGAG
CCTCTCTTAGCCAGGATCAAACATGACAGGAAGACAGTGGTCTGTCCCATCATAGATGTG
ATCAGTGATGACACTTTCGAGTACATGGCAGGTTCTGACATGACCTATGGCGGGTTCAAC
TGGAAGCTCAACTTTCGCTGGTATCCTGTTCCCCAAAGAGAAATGGACAGAAGGAAAGGT
GATCGGACTCTTCCTGTGAGAACACCTACAATGGCAGGAGGCCTTTTTTCAATAGACAGA
GATTACTTTCAGGAAATTGGAACATATGATGCTGGAATGGATATTTGGGGAGGAGAAAAC
CTAGAAATTTCCTTTAGGATTTGGCAGTGTGGAGGAACTTTGGAGATTGTTACTTGCTCA
CATGTTGGACATGTGTTTCGGAAAGCTACACCCTACACGTTTCCAGGAGGCACGGGGCAG
ATTATCAATAAAAATAACAGACGACTTGCAGAAGTATGGATGGATGAATTCAAGAATTTC
TTCTATATAATTTCTCCAGGTGTTACAAAGGTAGATTATGGAGATATATCATCAAGACTT
GGTCTAAGGCACAAACTCCAATGCAGACCATTCTCTTGGTACCTAGAGAATATTTATCCT
GATTCTCAGATTCCTCGTCACTATTTCTCTTTGGGAGAGATACGAAATGTGGAAACAAAT
CAGTGTCTAGATAACATGGCTAGAAAAGAGAATGAAAAAGTTGGAATTTTTAACTGTCAT
GGTATGGGAGGTAATCAGGTTTTCTCTTACACTGCCAACAAAGAAATTAGAACAGATGAC
CTTTGCTTGGATGTCTCCAAACTTAATGGCCCAGTCACAATGCTCAAATGCCACCACCTA
AAAGGCAACCAGCTTTGGGAGTATGACCCGGTGAAGTTGACCCTGCAGCATGTGAACAGT
AACCAGTGCCTGGACAAAGCCACAGACGAGGACAGCCAGGTGCCCAGCATCAGAGACTGC
AGCGGAAGCCGATCCCAGCAGTGGCTTCTTCGGAACGTCACCCTTCCAGAAATATTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 559 |
| Molecular Weight
| 64192.0 |
| Theoretical pI
| 7.77 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Polypeptide N-acetylgalactosaminyltransferase 1
MRKFAYCKVVLATSLIWVLLDMFLLLYFSECNKCDEKKERGLPAGDVLEPVQKPHEGPGE
MGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSV
VIVFHNEAWSTLLRTVHSVINRSPRHMLEEIVLVDDASERDFLKRPLESYVKKLKVPVHV
IRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRKTVVCPIIDV
ISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDR
DYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQ
IINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRLGLRHKLQCRPFSWYLENIYP
DSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDD
LCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATDEDSQVPSIRDC
SGSRSQQWLLRNVTLPEIF
|
| External Links |
|---|
| GenBank ID Protein
| AAA30532.1 |
| UniProtKB/Swiss-Prot ID
| Q07537 |
| UniProtKB/Swiss-Prot Entry Name
| GALT1_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| L07780 |
| GeneCard ID
| GALNT1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
