| Identification |
|---|
| BMDB Protein ID
| BMDBP00384 |
| Secondary Accession Numbers
| None |
| Name
| Threonine--tRNA ligase 2, cytoplasmic |
| Synonyms
|
Not Available
|
| Gene Name
| TARS3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Translation, ribosomal structure and biogenesis |
| Specific Function
| Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 21 |
| Locus
| Not Available |
| SNPs
| TARS3 |
| Gene Sequence
|
>2175 bp
ATGGCGGCCGAGGCCCTTGCGGCTGAGGCGGTGGCGTCGCGCCTGGCGCGGCAGGAGGAG
GACATCCGCTGGCTGTGGGCGGAGGTCCACCGTCTGAGGGACGAGCAGCTGAACGCGCCG
GACCGCTGCCAGGCCGAGGGGCCGTGCCTCACGCGCGAGGTAGCGCAGCTGCGGGCAGAG
AACCGCGAGCTGCGCCACTGCCTGTACCGTCTGCGGCTGTGCCTTGCGGAGGAGCTGAGC
CACCAAGCTCGGCTGGAGAGCGCGGCGCGGGCAGAGGCGGGGCGCGCGGCCGCAGGCGCG
CAGCCTCCTCCTAGTCAAAGCCTAGAAGAGGACGTTAAAAAGGAGATCGACCCTGACAAT
GAGGTGAAGAATCCACCAAATTTTATGAAGGAAAGATTGAAGTTTTTTGAAATACTGAAG
AAAGATCATCAGCTCTTACTTGCCATTTATGAAAAGAAGGGAGATTCAAGCAATGTGATC
ACAGTAAGAGTGGCTGATGGGAGAACAGTGAAAGGGGAAGCTTGGAAAACAACGCCTTAC
CAGGTGGCTGCAGAGATTAGTCAGGAGCTAGCGGAAACCACCGTGGTGGCTAAAGTGAAT
GGGGAGCTGTGGGACCTGGACCGCCCGCTGGAAGGGGACGCCACTGTGGAGCTCCTCACC
TTCGAGGATGAGGAGGCCCGGGCCGTATACTGGCACTCCAGTGCCCACGTACTCGGGGAA
GCCCTGGAGCTCCACTATGGAGGCCTCCTATGCTGCAGCCCACCCGGCGACGGCAGCTTT
CACTACGACGTGTACCTGGAAGACAGGGCCGTGTCCAGCGCAGAGCTGCCGGTGCTGGAG
AGCATGTGCCAGGCCATCATCAAAGAGCAGCAGCCATTTGAGAGACTGGAAGTCAGCACG
AAGGTCCTTCTAGACCTATTCAAGTACAATAAATTTAAATGCCGCATCCTGAAGGAGAAG
GTGGCCACGCCAACGACCACAGTTTACAGGTGCGGTCCACTAGTTGAACTTTGTAAAGGG
CCTCACGTAAGACACACTGGAACTATTAAGGTCATAAAAATTTTCAAGAATTCATTGGCA
TACTGGGCGGACAACCCTGAGATGGAAATGCTGCAGAGGGTCTACGGGGTGTCCTTTCCT
GACGAGCAGCGGATGGCTGCCTGGGAGGAGCTCCAGGAGGAGGCCAGGGCCCGGGACCAC
AGGACGATTGGGAAGGAACAGGAGCTTTTCTTTTTCCATGATCTGAGCCCCGGAAGCTGT
TTCTTTCTTCCTAGAGGAGCCTGCATTTATAACACACTGATAGACTTCATACGAGAGCAG
CACCACCAGCGCAACTTCACGGAGGTCCTGTCCCCCAACATGTACAGCTGCAAGCTCTGG
GAGGCTTCTGGACACTGGCAGCATTACAGTGAGAACATGTTCACCTTTGACATCGACAAG
GACACTTTCGCCCTTAAGCCCATGAATTGTCCAGGGCACTGTCTGATGTTTGCCCATCGT
CCACGGTCTTGGAGGGAAATGCCGATCAGACTTGCTGACTTCGGGGTTCTTCACAGGAAT
GAGCCATCAGGAGCTCTGAGTGGCTTGACCTGCGTCAGGCGCTTCCAGCAGGATGACGCT
CACATCTTCTGCACAGTGGGGCAGCTTGAAGAGGAGATAAAAGGGTGTTTGCAGTTTCTG
CAGTCTGTTTACTCAACGTTTGGCTTCTCCTTTCAATTAAATTTGTCAACAAGACCTGAA
AACTTCCTGGGAAAGATTGAGTTATGGGATGAAGCTGAAAAGCAACTACAGAATAGCTTG
ATGGAATTTGGGAAACCATGGAAGATAAACCCTGGAGAAGGAGCATTTTATGGTCCTAAA
ATTGATTTAGAAATCAAGGATGCTCTTGGCAGATACCATCAATGTGCTACAATCCAGCTG
GACTTTCAACTGCCTATAAGATTTAACCTTACATATGTGAGTAAGGATGGGGACGATAAG
AAGAACCCTGTGATCATTCACCAAGCCATTTTGGGGTCAGTGGAAAGAATGATAGCCATT
CTCTCTGAAAACTATGGGGGAAAATGGCCTTTCTGGCTGTCTCCTCGTCAGGTGATGGTC
ATCCCTGTGGGGCCAACTTGTGAAAAATACGCACTTCAGTGGTTGGAGAAAAGGAAGAGA
CAAATAATGCTGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 724 |
| Molecular Weight
| 83076.0 |
| Theoretical pI
| 6.07 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Probable threonyl-tRNA synthetase 2, cytoplasmic
MAAEALAAEAVASRLARQEEDIRWLWAEVHRLRDEQLNAPDRCQAEGPCLTREVAQLRAE
NRELRHCLYRLRLCLAEELSHQARLESAARAEAGRAAAGAQPPPSQSLEEDVKKEIDPDN
EVKNPPNFMKERLKFFEILKKDHQLLLAIYEKKGDSSNVITVRVADGRTVKGEAWKTTPY
QVAAEISQELAETTVVAKVNGELWDLDRPLEGDATVELLTFEDEEARAVYWHSSAHVLGE
ALELHYGGLLCCSPPGDGSFHYDVYLEDRAVSSAELPVLESMCQAIIKEQQPFERLEVST
KVLLDLFKYNKFKCRILKEKVATPTTTVYRCGPLVELCKGPHVRHTGTIKVIKIFKNSLA
YWADNPEMEMLQRVYGVSFPDEQRMAAWEELQEEARARDHRTIGKEQELFFFHDLSPGSC
FFLPRGACIYNTLIDFIREQHHQRNFTEVLSPNMYSCKLWEASGHWQHYSENMFTFDIDK
DTFALKPMNCPGHCLMFAHRPRSWREMPIRLADFGVLHRNEPSGALSGLTCVRRFQQDDA
HIFCTVGQLEEEIKGCLQFLQSVYSTFGFSFQLNLSTRPENFLGKIELWDEAEKQLQNSL
MEFGKPWKINPGEGAFYGPKIDLEIKDALGRYHQCATIQLDFQLPIRFNLTYVSKDGDDK
KNPVIIHQAILGSVERMIAILSENYGGKWPFWLSPRQVMVIPVGPTCEKYALQWLEKRKR
QIML
|
| External Links |
|---|
| GenBank ID Protein
| AAI48907.1 |
| UniProtKB/Swiss-Prot ID
| A6QNM8 |
| UniProtKB/Swiss-Prot Entry Name
| SYTC2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC148906 |
| GeneCard ID
| TARS3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
