| Identification |
|---|
| BMDB Protein ID
| BMDBP00385 |
| Secondary Accession Numbers
| None |
| Name
| L-threonine 3-dehydrogenase, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| TDH |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Cell wall/membrane/envelope biogenesis |
| Specific Function
| Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate, mediating L-threonine catabolism. |
| Pathways
|
- Amino-acid degradation
- Glycine from L-threonine: step 1/2
- L-threonine degradation via oxydo-reductase pathway
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 8 |
| Locus
| Not Available |
| SNPs
| TDH |
| Gene Sequence
|
>1122 bp
ATGCCAGTTGTTCGGGTGCTGCGGCGGGTCGCCTGCTGGATGCTGCAGAGCCCAGCCTGT
GGCTGCCGGGCTCCTGTCCTACCCAGCCGGTTTCTGGGGACCTCTCCTCGGCAGATTCCA
ATGGATGCCAACTTCCACTCCACTTCATTCTCAGAAGCAGACCAGCAGCGTGTCTTAATT
ACAGGGGGTCTTGGCCAGCTTGGAGTGGGTCTTGCTAGCTTTCTGAGGAAACGATTTGGG
AAGGACAATGTGATTCTATCTGACATTCGGAAGCCCCCGGAACACGTCTTTCTTAGTGGC
CCGTTTATTTATTCCGACATCCTGGATTACAAGAATCTTCGGGAGATTGTGGTGAACAAC
CGCATCACGTGGCTGTTCCATTACAGCGCCCTGCTCAGCGCAGTGGGAGAAGCAAACGTG
TCCCTGGCCAGAGCCGTGAACATCACTGGACTGCACAATGTCCTGGACGTTGCCGCAGAG
CACGGTCTGCGATTGTTTGTGCCAAGCACCATCGGGGCGTTTGGACCTACTTCTCCACGG
AACCCAACCCCTGACCTCTGCATCCAGAGACCCAGGACCATCTATGGGGTGTCCAAGGTC
CACGCTGAGCTTATGGGCGAGTATTATTATTACCGGTATGGATTAGACTTTCGGTGCCTG
AGATATCCTGGAATCATTTCTGCTGATTCCCAGCCTGGAGGAGGAACAACTGACTATGCG
GTCCAGATTTTCCATGAAGCTGTCAAGAATGGCAGATTTGAGTGCAACCTGAAACCCGAC
ACGAGGCTCCCAATGATGTACATTGACGACTGCCTCCGGGCCACCCTGGAGGTCATGGAG
GCCCCAGCAGAGTCCCTGTCCATGAGAACCTACAACATCAGCGCCATGAGCTTCACCCCC
GAGGAGCTGGCCCAGGAGGTGCTCAAGCATGTCCCAGAGCTCCAGGTCACCTACAATGTG
GATCCTGTCCGACAGGCCATAGCGGATAGTTGGCCAATGAACTTTGATGATAGCAACGCT
CGGAAGGACTGGGGATGGAAGCACGATTTTGACCTCCCAGAGCTGGTGACAACGATGTTG
AACTTCCACGGTTCTGAGAGCAGAGTTGCCCAGGCTAACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 373 |
| Molecular Weight
| 41846.0 |
| Theoretical pI
| 7.04 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>L-threonine 3-dehydrogenase, mitochondrial
MPVVRVLRRVACWMLQSPACGCRAPVLPSRFLGTSPRQIPMDANFHSTSFSEADQQRVLI
TGGLGQLGVGLASFLRKRFGKDNVILSDIRKPPEHVFLSGPFIYSDILDYKNLREIVVNN
RITWLFHYSALLSAVGEANVSLARAVNITGLHNVLDVAAEHGLRLFVPSTIGAFGPTSPR
NPTPDLCIQRPRTIYGVSKVHAELMGEYYYYRYGLDFRCLRYPGIISADSQPGGGTTDYA
VQIFHEAVKNGRFECNLKPDTRLPMMYIDDCLRATLEVMEAPAESLSMRTYNISAMSFTP
EELAQEVLKHVPELQVTYNVDPVRQAIADSWPMNFDDSNARKDWGWKHDFDLPELVTTML
NFHGSESRVAQAN
|
| External Links |
|---|
| GenBank ID Protein
| AAI12536.1 |
| UniProtKB/Swiss-Prot ID
| Q2KIR8 |
| UniProtKB/Swiss-Prot Entry Name
| TDH_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC112535 |
| GeneCard ID
| TDH |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
