1.0 2018-05-07 22:22:21 UTC 2020-05-20 21:04:52 UTC BMDBP00429 Enzyme PDE6C Involved in 3',5'-cyclic-GMP phosphodiesterase activity As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decreasing intracellular levels of cGMP. BMDB0001314 Cyclic GMP BMDB0001397 Guanosine monophosphate 26 >2568 bp ATGGGTGAGATCAGCCAAGAGACGGTGGAGAAATACCTGGAGGCCAACCCTCAGTTCGCC AAGGAGTATTTCAACAGGAAGTTGCAGGTGGAGGTGCCGAGCGGCGGGGCACAGGCACCG GCCAGCGCCTCCTTCCCCGGCCGGACGCTGGCGGAGGAGGCGGCCCTGTACCTGGAGCTG CTGGAGGTCTTGCTGGAGGAGGCGGGCAGCGTGGAGCTGGCGGCACACAGGGCCCTGCAG AGGCTGGCGCAGCTGCTGCAGGCAGACCGCTGCAGCATGTTCCTGTGTCGGGCCCGCAAC GGCACGCCGGAGGTGGCCTCCAAGCTGCTCGATGTCACCCCCACTTCCAAGTTTGAGGAC AACCTGGTGGTCCCCGACAGAGAAGCTGTGTTTCCGTTGGACGTTGGGATAGTGGGGTGG GTTGCTCACACGAAGAAAACCTTTAATGTTCCAGATGTGAAAAAGAACAGCCATTTTTCT GACTTCATGGACAAACAAACCGGGTATGTCACCAGGAACCTGCTGGCAACCCCCATCGTG ATGGGCAAGGAGGTTCTTGCTGTGTTTATGGCAGTTAACAAAGTAGACGCATCCGAATTT TCCAAACAGGATGAAGAGGTCTTTTCCAAATACCTCAGCTTTGTTTCTATCATCCTAAAG CTTCACCACACCAACTACCTGTACAATATTGAATCCCGAAGAAGTCAGATTCTTATGTGG TCAGCCAACAAAGTATTTGAAGAGCTCACAGATGTTGAGCGACAGTTTCACAAAGCACTC TACACTGTCAGGACATACCTGAACTGCGAACGATACTCCATTGGGCTGCTGGACATGACC AAGGAGAAGGAATTCTATGATGAGTGGCCAGTCAAGCTTGGAGAAGTCGAGCCTTACAAA GGTCCAAAGACACCAGATGGCAGAGAAGTCATCTTTTATAAAATCATCGATTACATTTTA CATGGAAAAGAAGAGATCAAAGTCATTCCGACACCTCCCATGGACCACTGGACTCTCATT AGTGGGTTGCCAACATATGTTGCTGAAAATGGATTTATCTGCAACATGCTGAACGCCCCG GCGGATGAATACTTCACGTTTCAGAAAGGACCTGTAGATGAAACTGGCTGGGTCATTAAA AATGTCTTGTCCCTGCCTATTGTCAACAAAAAGGAAGACATCGTGGGCGTAGCTACATTT TACAACAGGAAGGATGGAAAGCCTTTTGATGAATATGATGAGCACATCGCTGAGACTCTC ACACAGTTTCTTGGATGGTCTCTCTTAAATACTGACACCTATGAGAAAATGAATAAGCTG GAGAACAGAAAGGACATAGCCCAGGAAATGCTCATGAACCACACCAAGGCTACACCTGAT GAGATCAAGTCTATTTTGAAATTTAAAGAGAAGTTAAATATAGATGTAATTGAAGACTGT GAAGAAAAACAGCTTGTCACAATTTTGAAGGAGGACCTGCCAGACCCACGGACTGCAGAC CTGTATGAATTCCGCTTCAGGCACTTGCCCATCACAGAGCACGAACTGATTAAGTGTGGA CTTCGGCTGTTTTTTGAAATAAACGTGGTGGAGAAATTCAAAGTACCTGTAGAGGTTCTC ACCAGATGGATGTACACGGTGAGGAAGGGGTACCGGGCCGTCACATACCACAACTGGCGA CACGGGTTTAACGTGGGGCAGACCATGTTCACTTTGCTGATGACAGGAAGACTGAAGAAA TACTACACAGACCTTGAAGCCTTTGCCATGCTTGCTGCTGCCTTCTGCCACGACATTGAC CACAGAGGCACCAATAATTTGTATCAGATGAAGTCCACATCTCCGCTAGCAAGGCTTCAC GGCTCTTCCATCTTGGAGAGGCACCACCTGGAGTACAGTAAGACGCTCCTGCAGGATGAG AGTTTAAACATATTCCAGAACCTAAATAAACGCCAGTATGAAACAGTTATTCATTTGTTT GAAGTTGCGATAATAGCGACTGACCTGGCTTTATATTTCAAGAAGAGAACCATGTTTCAA AAAATTGTTGATGCCTGTGAAAAAATGGAAACTGAAGAAGAGGCCATCAAATATGTAACC ATTGATCCAACCAAAAAAGAGATTATCATGGCAATGATGATGACTGCGTGTGATCTGTCA GCTATAACCAAGCCCTGGGAGGTGCAAAGTCAGGTAGCACTCCTGGTTGCAAATGAATTT TGGGAACAAGGAGATCTGGAGAGAACAGTGCTGCAGCAACAACCCATTCCTATGATGGAC AGAAACAAAAAAGATGAACTACCTAAACTTCAAGTTGGATTTATTGACTTTGTCTGTACT TTTGTATATAAGGAGTTTTCACGGTTTCACAAAGAAATCACACCTATGCTGAATGGTCTT CAAAACAACAGAGTGGAATGGAAATCCCTAGCTGATGAGTATGATGAAAAGATGAAGGTA ATTGAAGAGATGAAAAAGCAGGAAGAAGGAAATACGACAGAAAAAGCTGTAGAAGATTCA GGAGGTGGTGGTGATGACAAGAAATCCAAAACATGTCTAATGTTGTAA 855 98798.0 5.53 None >Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' MGEISQETVEKYLEANPQFAKEYFNRKLQVEVPSGGAQAPASASFPGRTLAEEAALYLEL LEVLLEEAGSVELAAHRALQRLAQLLQADRCSMFLCRARNGTPEVASKLLDVTPTSKFED NLVVPDREAVFPLDVGIVGWVAHTKKTFNVPDVKKNSHFSDFMDKQTGYVTRNLLATPIV MGKEVLAVFMAVNKVDASEFSKQDEEVFSKYLSFVSIILKLHHTNYLYNIESRRSQILMW SANKVFEELTDVERQFHKALYTVRTYLNCERYSIGLLDMTKEKEFYDEWPVKLGEVEPYK GPKTPDGREVIFYKIIDYILHGKEEIKVIPTPPMDHWTLISGLPTYVAENGFICNMLNAP ADEYFTFQKGPVDETGWVIKNVLSLPIVNKKEDIVGVATFYNRKDGKPFDEYDEHIAETL TQFLGWSLLNTDTYEKMNKLENRKDIAQEMLMNHTKATPDEIKSILKFKEKLNIDVIEDC EEKQLVTILKEDLPDPRTADLYEFRFRHLPITEHELIKCGLRLFFEINVVEKFKVPVEVL TRWMYTVRKGYRAVTYHNWRHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAFCHDID HRGTNNLYQMKSTSPLARLHGSSILERHHLEYSKTLLQDESLNIFQNLNKRQYETVIHLF EVAIIATDLALYFKKRTMFQKIVDACEKMETEEEAIKYVTIDPTKKEIIMAMMMTACDLS AITKPWEVQSQVALLVANEFWEQGDLERTVLQQQPIPMMDRNKKDELPKLQVGFIDFVCT FVYKEFSRFHKEITPMLNGLQNNRVEWKSLADEYDEKMKVIEEMKKQEEGNTTEKAVEDS GGGGDDKKSKTCLML AAA30687.1 P16586 PDE6C_BOVIN 3JAB 3JBQ M37838 PDE6C