| Identification |
|---|
| BMDB Protein ID
| BMDBP00448 |
| Secondary Accession Numbers
| None |
| Name
| Isocitrate dehydrogenase [NADP], mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| IDH2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 21 |
| Locus
| Not Available |
| SNPs
| IDH2 |
| Gene Sequence
|
>1359 bp
ATGGCTGGTTACCTGCGAGTCGTACGCTCGCTCTGCAGAGCCTCTGGCTCCGGGTCGGCC
TGGGCGCCACGAGCCTTGACAGCCCCCAACTTGCAAGAGCAGCCGCGGCGCCACTATGCC
GACAAGAGGATCAAGGTGGCGAAGCCAGTGGTGGAGATGGACGGCGATGAGATGACCCGT
ATTATCTGGCAGTTCATCAAAGAGAAGCTCATCCTGCCCCACGTGGACGTCCAGCTCAAG
TATTTCGACCTGGGGCTCCCGAACCGTGACCAGACCAATGATCAGGTCACCATCGACTCC
GCGTTGGCCACCCAGAAGTACAGTGTGGCTGTGAAGTGTGCCACCATCACCCCCGACGAG
GCCCGTGTGGAAGAGTTCAAGCTGAAGAAGATGTGGAAGAGCCCCAATGGAACCATCCGG
AACATCCTCGGGGGAACGGTCTTCCGGGAGCCCATCATCTGTAAGAACATCCCGCGTCTC
GTCCCTGGCTGGACCAAGCCCATCACCATTGGCAGGCATGCCCACGGCGACCAGTACAAA
GCCACAGACTTTGTGGTTGACCGGGCTGGCACATTCAAGGTGGTCTTCACCCCGAAGGAT
GGCAGCGGCCCTAAGGAATGGGAGGTGTACAACTTTCCTGCTGGTGGCGTGGGCATGGGC
ATGTATAACACGGATGAGTCCATCTCAGGTTTTGCACACAGCTGCTTCCAGTATGCCATC
CAGAAGAAGTGGCCACTCTACATGAGCACCAAGAACACCATCCTGAAAGCTTACGACGGG
CGCTTCAAGGACATCTTCCAGGCCATCTTTGAGAAGCACTACAAGACTGAGTTCGACAAA
CATAAGATCTGGTACGAGCACCGGCTCATTGATGACATGGTGGCTCAGGTCCTCAAGTCC
TCAGGCGGCTTTGTGTGGGCCTGCAAGAACTACGATGGAGACGTGCAGTCGGACATCCTG
GCCCAGGGCTTTGGCTCCCTTGGTCTGATGACGTCCGTGCTGGTCTGCCCGGATGGGAAG
ACCATTGAGGCTGAGGCTGCTCATGGCACAGTCACCCGCCACTATCGGGAGCACCAGAAG
GGCCGGCCGACCAGCACCAACCCCATCGCCAGCATCTTTGCCTGGACGCGTGGCCTAGAA
CACCGGGGCAAGTTGGATGGGAACCAGGACCTCATCAGGTTCGCCCAGACCCTGGAGAAG
GTGTGCGTCGAGACGGTGGAGAGCGGAGCCATGACCAAGGACCTGGCGGGCTGCATCCAC
GGCCTCAGCAATGTGAAGCTGAACGAACACTTCCTGAACACCTCGGACTTCCTGGACACC
ATCAAGAGCAACCTGGACAGAGCTCTGGGCCAGCAGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 452 |
| Molecular Weight
| 50739.0 |
| Theoretical pI
| 8.95 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Isocitrate dehydrogenase [NADP], mitochondrial
MAGYLRVVRSLCRASGSGSAWAPAALTAPNLQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDKHKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKSNLDRALGQQ
|
| External Links |
|---|
| GenBank ID Protein
| CAA49207.1 |
| UniProtKB/Swiss-Prot ID
| Q04467 |
| UniProtKB/Swiss-Prot Entry Name
| IDHP_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| X69432 |
| GeneCard ID
| IDH2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
