| Identification |
|---|
| BMDB Protein ID
| BMDBP00453 |
| Secondary Accession Numbers
| None |
| Name
| Mitochondrial enolase superfamily member 1 |
| Synonyms
|
Not Available
|
| Gene Name
| ENOSF1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Cell wall/membrane/envelope biogenesis |
| Specific Function
| Plays a role in the catabolism of L-fucose, a sugar that is part of the carbohydrates that are attached to cellular glycoproteins. Catalyzes the dehydration of L-fuconate to 2-keto-3-deoxy-L-fuconate by the abstraction of the 2-proton to generate an enediolate intermediate that is stabilized by the magnesium ion. May down-regulate thymidylate synthase activity, possibly already at the RNA level, by promoting the degradation of TYMS mRNA via an antisense RNA-based mechanism. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 24 |
| Locus
| Not Available |
| SNPs
| ENOSF1 |
| Gene Sequence
|
>1332 bp
ATGGTGCACGGCAGGGTCTCCCGGCTCTCGGTCCACGACGTGCGCTTCCCCACGTCACTC
GGGGGCCACGGCTCGGACGCCATGCACACAGACCCTGACTACTCAGCAGCCTATGTTGTC
TTGGAGACGGATGCGGAAGACGGACTCAAGGGCTATGGAATTACCTTCACTCTGGGAAGA
GGCACTGAAGTTGTTGTCTGTGCTGTGAATGCTCTGGCCCCCCACGTGCTGAACAAGGAC
CTTGGCGAAATTGTTGGGGATTTCAGAGGTTTCTACAGGCAGCTCACGAGTGATGGGCAG
CTCAGATGGATCGGTCCTGAGAAGGGTGTGGTGCATCTGGCCACGGCGGCCGTGCTCAAT
GCCGTGTGGGACCTGTGGGCCAAGCAGGAGGGGAAGCCTCTGTGGAAGTTACTTGTTGAC
ATGGACCCCCGGACACTGGTGTCCTGCATCGATTTCAGGTACATCACTGACGTCCTGACG
GAGGAGGAAGCCTGCGAAATTCTGCGGCAAAGTCAGGTCGGGAAAAAAGAGCGAGAGGAG
CAAATGCTGGCACATGGCTACCCCGCCTACACCACATCGTGCGCCTGGCTGGGCTACCCT
GACGCCACGCTGAAGCAGCTCTGCAGCGAGGCGCTCAAGGACGGCTGGACCAGGTTTAAG
GTAAAAGTTGGTGCTGATCTCCAGGATGACATCCGTAGATGCCGACTCGTCAGAAACATG
ATTGGGCCTGAGAAGACACTGATGATGGACGCCAACCAGCGCTGGGACGTGCCCGAGGCC
GTGGAGTGGATGACAAAGCTGGCCGAGTTCAAGCCACTGTGGATTGAGGAGCCCACCTCC
CCTGACGACATTCTGGGACACGCTGCCATTTCCAAGGCACTGGCCCCCCTGGGCATCGGC
GTGGCCACAGGAGAACAGTGCCACAATAGAGTGATATTTAAGCAACTCCTGCAGGCGAAA
GCCCTGAAGTTTCTGCAGATTGACAGCTGCAGGCTGGGAAGTGTCAACGAGAACCTCTCA
GTGTTGCTGATGGCCAAGAAGTTTGAAATTCCTGTGTGCCCGCACGCCGGGGGAGTTGGC
CTCTGTGAACTGGTGCAGCATCTGATCATATTTGACTTCATATCCGTCTCTGCAAGCCTC
CAAGACAGGATGTGTGAATATGTCGACCACCTGCATGAGCATTTCAAGTACCCTGTGCTG
ATCAGGGAGGCTGCCTACATGCCTCCAAAGGATGCTGGTTATTCAACAGAAATGAAGGAG
GACTCGGTAAAGAGACACCGCTATCCAGATGGTGAAGTCTGGAAGAAGCTTCTAAGTGCT
CAAGGGAATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 443 |
| Molecular Weight
| 49621.0 |
| Theoretical pI
| 6.24 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Mitochondrial enolase superfamily member 1
MVHGRVSRLSVHDVRFPTSLGGHGSDAMHTDPDYSAAYVVLETDAEDGLKGYGITFTLGR
GTEVVVCAVNALAPHVLNKDLGEIVGDFRGFYRQLTSDGQLRWIGPEKGVVHLATAAVLN
AVWDLWAKQEGKPLWKLLVDMDPRTLVSCIDFRYITDVLTEEEACEILRQSQVGKKEREE
QMLAHGYPAYTTSCAWLGYPDATLKQLCSEALKDGWTRFKVKVGADLQDDIRRCRLVRNM
IGPEKTLMMDANQRWDVPEAVEWMTKLAEFKPLWIEEPTSPDDILGHAAISKALAPLGIG
VATGEQCHNRVIFKQLLQAKALKFLQIDSCRLGSVNENLSVLLMAKKFEIPVCPHAGGVG
LCELVQHLIIFDFISVSASLQDRMCEYVDHLHEHFKYPVLIREAAYMPPKDAGYSTEMKE
DSVKRHRYPDGEVWKKLLSAQGN
|
| External Links |
|---|
| GenBank ID Protein
| AAI12707.1 |
| UniProtKB/Swiss-Prot ID
| Q2KIA9 |
| UniProtKB/Swiss-Prot Entry Name
| ENOF1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC112706 |
| GeneCard ID
| ENOSF1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
