| Identification |
|---|
| BMDB Protein ID
| BMDBP00464 |
| Secondary Accession Numbers
| |
| Name
| Alpha-enolase |
| Synonyms
|
Not Available
|
| Gene Name
| ENO1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| Glycolytic enzyme the catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses (PubMed:7499243). May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). |
| Pathways
|
- Carbohydrate degradation
- Glycolysis
- Pyruvate from D-glyceraldehyde 3-phosphate: step 4/5
|
| Reactions
|
| 2-Phospho-D-glyceric acid → Phosphoenolpyruvic acid + Water |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 16 |
| Locus
| Not Available |
| SNPs
| ENO1 |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 434 |
| Molecular Weight
| 47326.0 |
| Theoretical pI
| 6.79 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Alpha-enolase
MSILKVHAREIFDSRGNPTVEVDLFTAKGLFRAAVPSGASTGIYEALELRDNDKTRYMGK
GVSKAVEHINKTIAPALVSKKLNVVEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCK
AGAVEKGVPLYRHIADLAGNAEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAENFRE
AMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKNAIGKAGYSDKV
VIGMDVAASEFYRSGKYDLDFKSPDDPSRYITPDELANLYKSFIRDYPVVSIEDPFDQDD
WEAWQKFTASAGIQVVGDDLTVTNPKRIAKAVSEKSCNCLLLKVNQIGSVTESLQACKLA
QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTVAPCRSERLAKYNQILRIEEELGSK
AKFAGRSFRNPLAK
|
| External Links |
|---|
| GenBank ID Protein
| AAD33073.1 |
| UniProtKB/Swiss-Prot ID
| Q9XSJ4 |
| UniProtKB/Swiss-Prot Entry Name
| ENOA_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF149256 |
| GeneCard ID
| ENO1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
