1.0 2018-05-07 22:22:32 UTC 2020-05-20 21:04:07 UTC BMDBP00471 BMDBP03022 Enzyme IDH3B Energy production and conversion Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. BMDB0000193 Isocitric acid BMDB0000208 Oxoglutaric acid BMDB0000547 Magnesium BMDB0000902 NAD BMDB0001333 Manganese BMDB0001487 NADH 13 >1152 bp ATGGCTGCCCTCAGCCGTGTCCGCTGGCTGACCCGAGCACTGGTCGCCGCTCCGAATCCC GGAGCATGGAGGAGCCTGTGTACCTCAACCGTGGCGCAAGCCTCCTCGCGGACCCAGGGC GAGGATGTGAGGGTGGAGGGCGCCTTTCCCGTGACTATGCTGCCAGGAGACGGCGTGGGG CCTGAGCTGATGCACGCTGTCAAGGAGGTGTTCAAGGCTGCCTCTGTCCCAGTGGAGTTC CAGGAGCATCACCTGAGCGAGGTGCAGAATATGGCATCTGAGGAGAAGCTGGAGCAGGTG CTGAGTTCCATGAAGGAGAACAAAGTGGCCATCATTGGAAAGATCCACACCCCAATGGAG TATAAAGGGGAGCTAGCCTCCTATGATATGCGGCTGAGGCGGAAGTTGGACTTGTTTGCC AATGTGGTCCATGTGAAGTCACTTCCTGGGTACAAGACTCGACACAACAATCTAGATTTG GTGATTATTCGAGAGCAGACAGAAGGGGAGTACAGTTCTCTGGAACACGAGAGTGCGAGG GGTGTGATTGAGTGCTTGAAGATTGTCACTCGAACCAAATCACAGCGGATTGCAAAGTTC GCCTTTGACTATGCCACTAAGAAGGGGCGGGGCAAGGTCACGGCTGTCCACAAGGCCAAT ATCATGAAACTGGGGGATGGGTTGTTCCTGCAGTGCTGTGAGGAAGTTGCTGAACTGTAT CCCAAGATCAAGTTTGAGAAAATGATCATAGACAACTGCTGCATGCAGCTGGTGCAGAAT CCTTACCAGTTTGACGTGCTGGTGATGCCCAATCTCTATGGGAACATTATTGACAATCTG GCTGCTGGCCTGGTTGGGGGAGCTGGTGTGGTCCCTGGTGAGAGCTACAGTGCAGAGTAC GCAGTGTTTGAGACGGGTGCCCGGCATCCATTTGCCCAGGCAGTGGGCAGGAATATAGCC AACCCCACAGCCATGCTGCTGTCAGCTTCCAACATGCTGCGGCATCTCAATCTCGAGCAT CACTCCAACATGATTGCAGAGGCAGTGAAGAAGGTGATTAAAGTTGGCAAGGTTCGAACT TCTGACATGGGTGGTTATGCCACCTGCCAAGACTTCACTGAGGCTGTCATTGGTGCCCTG TCCAACCCATAG 385 42497.0 8.91 None >Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial MAALSRVRWLTRALVAAPNPGAWRSLCTSTVAQASSRTQGEDVRVEGAFPVTMLPGDGVG PELMHAVKEVFKAASVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME YKGELASYDMRLRRKLDLFANVVHVKSLPGYKTRHNNLDLVIIREQTEGEYSSLEHESAR GVIECLKIVTRTKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY PKIKFEKMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEHHSNMIAEAVKKVIKVGKVRT RDMGGYSTTTDFIKSVIGHLHPYGG AAC83166.1 O77784 IDH3B_BOVIN AF090321 IDH3B