| Identification |
|---|
| BMDB Protein ID
| BMDBP00583 |
| Secondary Accession Numbers
| None |
| Name
| Uridine-cytidine kinase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| UCK1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Nucleotide transport and metabolism |
| Specific Function
| Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor (By similarity). |
| Pathways
|
- CTP biosynthesis via salvage pathway
- CTP from cytidine: step 1/3.
- Pyrimidine Metabolism
- UMP biosynthesis via salvage pathway
- UMP from uridine: step 1/1
|
| Reactions
|
| Deoxycytidine + Adenosine triphosphate → dCMP + ADP |
details
|
| Uridine + Adenosine triphosphate → Uridine 5'-monophosphate + ADP |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 11 |
| Locus
| Not Available |
| SNPs
| UCK1 |
| Gene Sequence
|
>834 bp
ATGGCTTCGGCTGGAGGCGGCGACTGCGAGGGCGCCGGGCCCGAGGCGGACCGTCCTCAC
CAGCGGCCCTTCTTGATCGGCGTGAGCGGCGGCACCGCGAGCGGCAAGTCCACTGTGTGC
GAGAAGATCATGGAGCTGCTGGGACAGAATGAAGTGGATCACCGGCAGCGCAAGCTGGTC
ATCTTGAGCCAAGACAGGTTCTATAAGGTCCTGACCGCGGAGCAGAAGGCCAAGGCCTTG
AAGGGACAGTACAACTTCGACCACCCAGATGCTTTTGATAACGATTTGATGCACAGGACT
CTGAAAAACATCGTGGAGGGCAAAACGGTCGAGGTCCCCACCTATGATTTTGTGACACAC
TCAAGGCTCGCGGAGACCACGGTGGTCTACCCCGCAGACGTGGTCCTGTTCGAGGGCATC
CTGGTCTTCTACAGCCAGGAGATACGGGACATGTTCCACCTGCGCCTCTTCGTGGACACC
GACTCCGACGTCAGGCTGTCTCGGAGAGTTCTCCGGGATGTGCAGCGGGGCCGGGACCTG
GAGCAGATCCTGACGCAGTACACCACCTTCGTCAAGCCAGCCTTCGAGGAGTTCTGCCTG
CCGACAAAGAAGTACGCAGACGTGATCATCCCTCGAGGGGTTGACAACATGGTGGCCATC
AACCTCATCGTGCAGCACATCCAGGACATCCTCAACGGCGACATCTGCAAGTGGCACCGC
GCGGGGGCCAACGGGCGCAGCCACAAGAGGACATTCCCAGAGCCGGGGGAGCACCCTGCG
GTACTGGCCTCGGGCAAGCGCTCGCACCTGGAGTCCAGCAGCAGGCCACACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 277 |
| Molecular Weight
| 31195.0 |
| Theoretical pI
| 7.4 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Uridine-cytidine kinase 1
MASAGGGDCEGAGPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVDHRQRKLV
ILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTH
SRLAETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVQRGRDL
EQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHR
AGANGRSHKRTFPEPGEHPAVLASGKRSHLESSSRPH
|
| External Links |
|---|
| GenBank ID Protein
| AAI20305.1 |
| UniProtKB/Swiss-Prot ID
| Q0P5A4 |
| UniProtKB/Swiss-Prot Entry Name
| UCK1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC120304 |
| GeneCard ID
| UCK1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
