| Identification |
|---|
| BMDB Protein ID
| BMDBP00620 |
| Secondary Accession Numbers
| None |
| Name
| Malate dehydrogenase, cytoplasmic |
| Synonyms
|
Not Available
|
| Gene Name
| MDH1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Not Available |
| Pathways
|
- LPS and Citrate Signaling and Inflammation
- Pyruvate Metabolism
- Transfer of Acetyl Groups into Mitochondria
- Warburg Effect
|
| Reactions
|
| Oxalacetic acid + Hydrogen + NADPH → NAD + L-Malic acid |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 11 |
| Locus
| Not Available |
| SNPs
| MDH1 |
| Gene Sequence
|
>1005 bp
ATGTCTGAACCAATCCGAGTCCTTGTGACTGGAGCAGCTGGTCAAATTGCATATTCGCTG
CTATACAGTATTGGAAATGGATCTGTCTTCGGTAAAGACCAGCCTATCATTCTCGTGCTG
TTGGATATCACTCCAATGATGGGTGTCCTGGATGGTGTCCTGATGGAGCTGCAAGACTGT
GCCCTTCCCCTCCTGAAAGATGTCATCGCAACAGATAAAGAAGAGATTGCCTTCAAAGAC
CTGGATGTGGCCATTCTTGTGGGCTCCATGCCAAGAAGGGATGGCATGGAGAGGAAAGAT
TTACTCAAAGCAAATGTGAAAATCTTCAAATGCCAGGGTGCAGCCTTGGACAAATATGCC
AAGAAGTCAGTTAAGGTTATTGTGGTGGGAAATCCAGCCAATACCAACTGCCTGACTGCC
TCCAAGTCGGCACCATCCATCCCCAAGGAGAACTTCAGTTGCTTGACTCGTTTGGATCAC
AACCGAGCTAAAGCTCAGATTGCTCTTAAACTTGGAGTGACTTCTGATGATGTAAAGAAT
GTCATCATCTGGGGAAACCATTCCTCAACTCAGTATCCAGATGTCAACCATGCCAAAGTG
AAACTGCAAGGAAAGGAAGTTGGTGTTTACGAAGCTCTGAAAGATGACAGCTGGCTCAAG
GGAGAATTCATCACGACTGTGCAGCAGCGCGGTGCTGCTGTCATCAAGGCACGAAAACTG
TCCAGTGCAATGTCGGCTGCAAAGGCCATCTGTGACCACGTCAGAGACATCTGGTTTGGA
ACCCCAGAGGGAGAGTTTGTGTCCATGGGCATTATCTCCGATGGCAACTCCTATGGTATT
CCTGATGATCTGCTTTACTCGTTCCCCGTTACAATCAAGGATAAGACCTGGAAAGTTGTT
GAAGGTCTCCCTATTAATGACTTCTCACGTGAGAAGATGGATCTTACTGCAAAGGAACTG
GCAGAAGAGAAAGAAACTGCATTTGAATTTCTTGCCTCTGCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 334 |
| Molecular Weight
| 36438.0 |
| Theoretical pI
| 6.53 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Malate dehydrogenase, cytoplasmic
MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDC
ALPLLKDVIATDKEEIAFKDLDVAILVGSMPRRDGMERKDLLKANVKIFKCQGAALDKYA
KKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTSDDVKN
VIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFITTVQQRGAAVIKARKL
SSAMSAAKAICDHVRDIWFGTPEGEFVSMGIISDGNSYGIPDDLLYSFPVTIKDKTWKVV
EGLPINDFSREKMDLTAKELAEEKETAFEFLASA
|
| External Links |
|---|
| GenBank ID Protein
| AAI02134.1 |
| UniProtKB/Swiss-Prot ID
| Q3T145 |
| UniProtKB/Swiss-Prot Entry Name
| MDHC_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC102133 |
| GeneCard ID
| MDH1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
