| Identification |
|---|
| BMDB Protein ID
| BMDBP00653 |
| Secondary Accession Numbers
| None |
| Name
| N-acetyllactosaminide alpha-1,3-galactosyltransferase |
| Synonyms
|
Not Available
|
| Gene Name
| GGTA1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in manganese ion binding |
| Specific Function
| Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid. Preferentially glycosylates proteins, can synthesize galactose-alpha(1,3)-galactose on glycoproteins but cannot synthesize the glycolipid called isoglobotrihexosylceramide or isogloboside 3 (iGb3). |
| Pathways
|
- Protein glycosylation
- Protein modification
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 11 |
| Locus
| 11q26 |
| SNPs
| GGTA1 |
| Gene Sequence
|
>1107 bp
GCAGACGATGAGGAGAAAATAATGAATGTCAAAGGAAAAGTGATTCTGTCAATGCTGGTT
GTCTCAACTGTCATTGTTGTGTTTTGGGAATATATCCACAGCCCAGAAGGCTCTTTGTTC
TGGATAAACCCATCAAGAAACCCAGAAGTTGGTGGCAGCAGCATTCAGAAGGGCTGGTGG
CTTCCGAGATGGTTTAACAATGGTTACCATGAAGAAGATGGAGACATAAACGAAGAAAAG
GAACAAAGAAACGAAGACGAAAGCAAGCTTAAGCTATCGGACTGGTTCAACCCATTTAAA
CGCCCCGAGGTTGTGACCATGACGAAGTGGAAGGCTCCAGTGGTGTGGGAAGGCACTTAC
AACAGAGCCGTCTTAGACAATTATTATGCCAAGCAGAAAATTACCGTCGGCCTGACGGTT
TTCGCCGTCGGAAGATACATTGAGCATTACTTGGAGGAGTTCTTAACGTCTGCTAATAAG
CACTTCATGGTGGGCCACCCAGTCATCTTTTATATCATGGTAGATGATGTCTCCAGGATG
CCTTTGATAGAGTTGGGTCCTCTGCGCTCCTTCAAAGTGTTTAAGATCAAGCCTGAGAAG
AGGTGGCAGGACATCAGCATGATGCGCATGAAGACTATCGGGGAGCACATTGTGGCCCAC
ATCCAGCATGAGGTTGACTTCCTTTTCTGCATGGATGTGGACCAGGTCTTCCAAGACAAG
TTTGGGGTGGAGACCCTGGGCGAGTCGGTGGCCCAGCTACAAGCCTGGTGGTACAAGGCA
GATCCCAATGACTTCACCTACGAGAGGCGGAAGGAGTCTGCAGCATACATTCCCTTCGGC
GAAGGGGATTTTTATTACCATGCAGCCATTTTTGGGGGAACACCCACTCAGGTCCTTAAC
ATCACCCAGGAATGCTTCAAAGGAATCCTCAAGGACAAGAAAAATGACATAGAAGCCCAA
TGGCATGATGAAAGCCATCTAAACAAGTATTTCCTTCTCAACAAACCTACTAAAATCTTA
TCCCCGGAATACTGCTGGGATTATCACATAGGCCTACCTGCGGATATTAAGCTTGTCAAG
ATGTCTTGGCAGACAAAAGAGTATAAT
|
| Protein Properties |
|---|
| Number of Residues
| 368 |
| Molecular Weight
| 43247.0 |
| Theoretical pI
| 6.52 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>N-acetyllactosaminide alpha-1,3-galactosyltransferase
MNVKGKVILSMLVVSTVIVVFWEYIHSPEGSLFWINPSRNPEVGGSSIQKGWWLPRWFNN
GYHEEDGDINEEKEQRNEDESKLKLSDWFNPFKRPEVVTMTKWKAPVVWEGTYNRAVLDN
YYAKQKITVGLTVFAVGRYIEHYLEEFLTSANKHFMVGHPVIFYIMVDDVSRMPLIELGP
LRSFKVFKIKPEKRWQDISMMRMKTIGEHIVAHIQHEVDFLFCMDVDQVFQDKFGVETLG
ESVAQLQAWWYKADPNDFTYERRKESAAYIPFGEGDFYYHAAIFGGTPTQVLNITQECFK
GILKDKKNDIEAQWHDESHLNKYFLLNKPTKILSPEYCWDYHIGLPADIKLVKMSWQTKE
YNVVRNNV
|
| External Links |
|---|
| GenBank ID Protein
| AAA30558.1 |
| UniProtKB/Swiss-Prot ID
| P14769 |
| UniProtKB/Swiss-Prot Entry Name
| GGTA1_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| J04989 |
| GeneCard ID
| GGTA1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
