| Identification |
|---|
| BMDB Protein ID
| BMDBP00797 |
| Secondary Accession Numbers
| None |
| Name
| Methionine aminopeptidase 2 |
| Synonyms
|
Not Available
|
| Gene Name
| METAP2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Translation, ribosomal structure and biogenesis |
| Specific Function
| Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| METAP2 |
| Gene Sequence
|
>1434 bp
ATGGCGGGTGTGGAGGAGGCAGCGTCCTGCGGGAGCCACCTGAATGGCGACCTGGATCCA
GACGAAAGAGAGGAGGGAGCTGCCTCTACGGCTGAGGAAGCGGCCAAGAAAAAAAAACGG
AAGAAGAAGAAGAGTAAAGGGGCTGCCACAGGGCAACAGGAACCTGATAAAGAAGCAGGA
GCCTCAGTTGATGAGGTGACAAGACAATTGGAAAGACAAGCATTGGAAGAGAAAGAAAAA
GATGATGATGATGAAGATGGAGATGGTGACGGAGATGGAGCAACTGGAAAGAAGAAGAAA
AAGAAGAAGAAGAAGAGAGGACCAAAAGTTCAAACAGACCCTCCCTCAGTTCCAATATGT
GACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAA
GATGGGCGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAAGCT
AGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACAAGTTAGAAAA
TATGTTATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAGAAGATGGAA
GACTGTTCACGAAAGTTAATAAAAGAGAATGGATTAAACGCAGGCCTGGCATTTCCTACT
GGGTGTTCTCTGAATAACTGTGCTGCCCATTATACTCCCAATGCTGGTGACACAACAGTA
TTACAGTATGATGACATCTGTAAGATAGACTTTGGAACACATATAAGTGGTAGGATTATC
GATTGTGCTTTTACTGTCACTTTTAATCCCAAATATGATACATTATTAAAAGCTGTCAAA
GATGCCACTAACACTGGAATAAAGTGTGCCGGAATTGATGTTCGTCTCTGTGATGTTGGT
GAGGCTATCCAAGAAGTTATGGAATCCTATGAAGTTGAAATAGATGGGAAGACATATCAA
GTGAAACCAATCCGTAATCTAAATGGACATTCAATTGGGCCATATAGAATACATGCTGGG
AAAACAGTGCCCATTGTGAAAGGAGGAGAGGCAACAAGAATGGAGGAAGGAGAAGTATAT
GCCATTGAAACCTTTGGTAGCACAGGAAAAGGTGTGGTTCATGATGATATGGAATGTTCA
CATTACATGAAAAATTTTGATGTTGGACATGTGCCAATAAGGCTTCCAAGAACAAAACAC
TTGTTAAATGTCATCAATGAAAACTTTGGCACTCTTGCCTTCTGCCGCAGATGGCTGGAT
CGTTTGGGAGAAAGTAAATACTTGATGGCTCTGAAGAATCTGTGTGACTTGGGCATTGTA
GACCCATATCCACCATTATGTGACATTAAAGGATCATATACAGCACAGTTTGAACACACC
ATACTTTTGCGTCCAACATGTAAAGAAGTTGTCAGCCGAGGAGATGACTATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 477 |
| Molecular Weight
| 52812.0 |
| Theoretical pI
| 5.71 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Methionine aminopeptidase 2
MAGVEEAASCGSHLNGDLDPDEREEGAASTAEEAAKKKKRKKKKSKGAATGQQEPDKEAG
ASVDEVTRQLERQALEEKEKDDDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPIC
DLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRK
YVMSWIKPGMTMIEICEKMEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTV
LQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDVG
EAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGPYRIHAGKTVPIVKGGEATRMEEGEVY
AIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLD
RLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
|
| External Links |
|---|
| GenBank ID Protein
| AAI02825.1 |
| UniProtKB/Swiss-Prot ID
| Q3ZC89 |
| UniProtKB/Swiss-Prot Entry Name
| MAP2_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC102824 |
| GeneCard ID
| METAP2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
