| Identification |
|---|
| BMDB Protein ID
| BMDBP00827 |
| Secondary Accession Numbers
| None |
| Name
| Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 |
| Synonyms
|
Not Available
|
| Gene Name
| GFPT2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Cell wall/membrane/envelope biogenesis |
| Specific Function
| Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins (By similarity). |
| Pathways
|
- Alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1
- Amino Sugar Metabolism
- Glutamate Metabolism
- Nucleotide-sugar biosynthesis
- UDP-N-acetyl-alpha-D-glucosamine biosynthesis
|
| Reactions
|
| Fructose 6-phosphate + L-Glutamine → Glucosamine 6-phosphate + L-Glutamic acid |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 7 |
| Locus
| Not Available |
| SNPs
| GFPT2 |
| Gene Sequence
|
>2049 bp
ATGTGCGGAATCTTTGCCTACATGAATTACAGAGTCCCCCGGACAAGGAAGGAGATTTTT
GAAACCCTCATCAAGGGCCTGCAGCGGCTTGAGTACAGAGGCTATGACTCAGCAGGTGTG
GCAATTGATGGAAATAATAATGAAGTCAAAGAAAGGCATATCCAGCTCGTCAAGAAAAGA
GGAAATGTCAAAGCTCTTGATGAAGAACTTTACAAACAAGACAGCATGGACTTAAAAGTG
GAGTTTGAGACCCACTTTGGCATTGCCCACACACGGTGGGCCACTCACGGGGTCCCCAGT
GCTGTCAACAGCCACCCGCAGCGCTCAGACAAGGGCAACGAATTCGTTGTCATCCATAAT
GGGATCATCACAAATTACAAAGACCTGAGGAAATTTCTGGAAAGCAAAGGCTATGAGTTT
GAGTCAGAAACAGATACAGAAACCATTGCCAAGCTGATTAAATATGTGTTCGACAACAGA
GAAACCGAGGACATTACATTTTCAACACTGGTGGAGAGAGTCATTCAGCAGCTGGAAGGC
GCATTTGCCTTGGTTTTCAAGAGCATCCACTACCCTGGAGAAGCCGTGGCCACAAGGAGA
GGCAGTCCCCTACTCATCGGAGTAAGGAGCAAATACAAACTCTCCACAGAACAGATCCCC
GTCTTATATAGGACACGCAATATTGAGAATGTGAAGAATATCTGTAAAACAAGGATGAAG
AGGCTGGACAGCTCGACCTGCCTTCACGCTGTGGGCAATAAAGCAGTGGAATTCTTTTTT
GCTTCTGATGCAAGTGCTATCATAGAGCACACCAACCGGGTCATCTTCCTTGAGGATGAT
GACATTGCCGCAGTGGCTGATGGGAAACTCTCTATTCACCGGGTCAAGCGTTTGGCTAGT
GATGACCCATCTCGAGCCATCCAGACCTTGCAGATGGAATTGCAGCAAATCATGAAAGGT
AACTTCAGTGCATTTATGCAAAAGGAGATATTTGAACAGCCAGAATCCGTTTTCAATACC
ATGAGAGGTCGAGTGAATTTTGAGACCAACACAGTGCTCCTGGGTGGCTTGAAAGACCAC
TTGAAGGAGATCAGACGATGCCGACGGCTCATTGTGATTGGCTGTGGGACCAGCTACCAC
GCCGCTGTGGCCACGCGGCAAGTTTTGGAGGAACTGACCGAGCTCCCCGTGATGGTTGAA
CTTGCTAGTGATTTTCTGGACAGGAACACACCTGTGTTCAGGGATGACGTTTGCTTTTTC
ATAAGCCAGTCAGGGGAGACTGCAGACACCCTCCTGGCACTGCGCTACTGCAAGGACCGC
CGAGCTCTGACCGTGGGCGTCACCAACACCGTGGGCAGCTCCATCTCCCGCGAGACGGAC
TGCGGCGTCCACATCAACGCAGGGCCGGAGATCGGTGTGGCCAGCACCAAGGCTTACACC
AGTCAGTTCATCTCCTTGGTGATGTTTGGTTTGATGATGTCTGAAGACCGCATTTCACTG
CAAAACAGAAGGCGAGAGATCATCCATGGCCTGAAATCTCTACCCGAGCTGATCAAGGAG
GTGCTGTCCCTGGATGAGAAGATCCACGACCTGGCCCTGGAGCTCTACACACAAAGGTCA
CTTCTGGTCATGGGGCGAGGCTACAACTATGCCACATGCCTGGAAGGAGCCCTGAAAATT
AAAGAGATAACCTACATGCACTCAGAAGGCATCCTGGCTGGAGAGTTGAAGCACGGCCCC
CTGGCGCTGATTGATAAGCAGATGCCTGTCATCATGGTCATCATGAAGGATCCTTGCTTT
GCCAAATGCCAGAACGCCCTGCAGCAGGTCACAGCGCGCCAGGGTCGCCCGATTATACTG
TGCTCCAAGGACGACACTGAAAGCTCCAAGTTTGCATATAAAACGATCGAGCTGCCCCAC
ACCGTAGACTGCCTGCAGGGCATCCTGAGTGTGATTCCACTGCAGCTCCTCTCCTTCCAC
CTGGCTGTACTCCGAGGATATGACGTTGACTTCCCCAGAAATCTGGCCAAGTCTGTAACC
GTGGAATGA
|
| Protein Properties |
|---|
| Number of Residues
| 682 |
| Molecular Weight
| 77081.0 |
| Theoretical pI
| 7.72 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2
MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNNEVKERHIQLVKKR
GNVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRSDKGNEFVVIHN
GIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEG
AFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYRTRNIENVKNICKTRMK
RLDSSTCLHAVGNKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRLAS
DDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDH
LKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFF
ISQSGETADTLLALRYCKDRRALTVGVTNTVGSSISRETDCGVHINAGPEIGVASTKAYT
SQFISLVMFGLMMSEDRISLQNRRREIIHGLKSLPELIKEVLSLDEKIHDLALELYTQRS
LLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCF
AKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFH
LAVLRGYDVDFPRNLAKSVTVE
|
| External Links |
|---|
| GenBank ID Protein
| AAI23625.1 |
| UniProtKB/Swiss-Prot ID
| Q08DQ2 |
| UniProtKB/Swiss-Prot Entry Name
| GFPT2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC123624 |
| GeneCard ID
| GFPT2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
