| Identification |
|---|
| BMDB Protein ID
| BMDBP00966 |
| Secondary Accession Numbers
| None |
| Name
| Ubiquitin-conjugating enzyme E2 E3 |
| Synonyms
|
Not Available
|
| Gene Name
| UBE2E3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ATP binding |
| Specific Function
| Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest. |
| Pathways
|
- Protein modification
- Protein ubiquitination
- Ubiquitin–Proteasome Pathway
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 2 |
| Locus
| Not Available |
| SNPs
| UBE2E3 |
| Gene Sequence
|
>624 bp
ATGTCCAGTGATCGGCAGAGATCCGATGATGAGAGTCCCAGCACCAGCAGCGGTAGCTCA
GATGCAGACCAGCGAGACCCAGCCGCTCCAGAGCCTGAAGAACAAGAAGAAAGAAAACCG
TCTGCCACCCAGCAGAAGAAAAACACCAAACTCTCTAGCAAAACCACTGCTAAATTATCC
ACTAGTGCTAAAAGAATTCAGAAGGAGCTAGCTGAAATAACCCTTGATCCTCCTCCTAAC
TGCAGTGCTGGGCCTAAAGGAGATAACATTTATGAATGGAGATCGACTATACTTGGTCCA
CCAGGTTCTGTATATGAAGGTGGTGTGTTTTTTCTGGATATCACATTTTCATCCGATTAT
CCATTTAAGCCACCAAAGGTTACTTTCCGCACCAGAATCTATCACTGCAACATCAATAGT
CAGGGAGTCATCTGCCTGGACATCCTTAAAGACAACTGGAGTCCTGCTTTGACTATTTCA
AAGGTTTTGCTGTCAATTTGTTCTCTTTTGACAGACTGCAACCCTGCGGATCCTCTGGTT
GGAAGCATAGCCACTCAGTATTTGACCAACAGAGCAGAACATGACAGGATAGCCAGACAG
TGGACCAAGCGATACGCAACATAA
|
| Protein Properties |
|---|
| Number of Residues
| 207 |
| Molecular Weight
| 22913.0 |
| Theoretical pI
| 7.25 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Ubiquitin-conjugating enzyme E2 E3
MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERKPSATQQKKNTKLSSKTTAKLS
TSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDY
PFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLV
GSIATQYLTNRAEHDRIARQWTKRYAT
|
| External Links |
|---|
| GenBank ID Protein
| AAI11219.1 |
| UniProtKB/Swiss-Prot ID
| Q2T9X7 |
| UniProtKB/Swiss-Prot Entry Name
| UB2E3_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC111218 |
| GeneCard ID
| UBE2E3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
