| Identification |
|---|
| BMDB Protein ID
| BMDBP01019 |
| Secondary Accession Numbers
| None |
| Name
| Dehydrogenase/reductase SDR family member 9 |
| Synonyms
|
Not Available
|
| Gene Name
| DHRS9 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. Plays also a role in the biosynthesis of retinoic acid from retinaldehyde. Can utilize both NADH and NADPH. |
| Pathways
|
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 2 |
| Locus
| Not Available |
| SNPs
| DHRS9 |
| Gene Sequence
|
>960 bp
ATGCTCTTTTGGCTGTTAGTCCTTCTGATCCTTTGTGGTTTTCTGTGGAATTATAAAAGA
CAGCTAAAGATCGCAAACATCACTGATAAGTACATTTTCATCACTGGGTGTGACACTGGC
TTTGGAAACTTGGCAGCCAGAACTTTTGATAAGAAAGGATTTCATGTAATTGCTGCCTGC
CTAACTGAATCAGGATCAACAGCTTTAAAGGCAGAAACTTCAGAGAGGCTTCATACCGTG
CTCCTGGATGTAACTGACCCAGAAAATGTCAAGAGGGCTGCCCAGTGGGTGAAGAACCAA
GTTGGGGAGAAAGGTCTCTGGGGTCTGATCAACAACGCTGGCATTCTTGGTGTGCTGGCA
CCCAATGACTGGCTGACAGTTGAGGACTACAGAGAACCTGTTGAAGTGAACCTGTTTGGA
CTCATCAGTGTCACGTTAAACATGCTTCCCTTGGTCAAAAAGGCTCGAGGGAGAATTATC
AATGTCTCCAGCATTGGGGGTCGGCTTGCATTTGGTGGAGGGGGCTATTCGCCATCTAAA
TATGCAGTAGAAGGCTTCAATGACAGCTTAAGGCGGGACATGAAAGCTTTTGGTGTGCAT
GTCGCTTGCATCGAACCAGGATTGTTCAAAACCAATTTGTCAGATCCAGAAAAGACTGCT
GAAAAGAAACTTGCCATTTGGAAGCATCTGTCTCCAGACATCAAACAACAATATGGAGAA
AGCTACATTGAGAAAAGCCTAGAACAATTGAAAGGCACTGCATCCTTTGTGAACGTGGAT
CTGTCCCTGGTGGTGGAGTGCATGGACCATGCTCTCACAAGTCTCTTCCCTAAAACCCGT
TATGCTGCTGGAAAAGATGCCAAAACTTTCTGGATCCCTCTGTCTCACATGCCAGCAGTT
TTGCAAGACTTTTTATTGTTGAAACAGAAAGTAGAGCTGGCTAATCCCAGGGCAGTATGA
|
| Protein Properties |
|---|
| Number of Residues
| 319 |
| Molecular Weight
| 35388.0 |
| Theoretical pI
| 9.1 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Dehydrogenase/reductase SDR family member 9
MLFWLLVLLILCGFLWNYKRQLKIANITDKYIFITGCDTGFGNLAARTFDKKGFHVIAAC
LTESGSTALKAETSERLHTVLLDVTDPENVKRAAQWVKNQVGEKGLWGLINNAGILGVLA
PNDWLTVEDYREPVEVNLFGLISVTLNMLPLVKKARGRIINVSSIGGRLAFGGGGYSPSK
YAVEGFNDSLRRDMKAFGVHVACIEPGLFKTNLSDPEKTAEKKLAIWKHLSPDIKQQYGE
SYIEKSLEQLKGTASFVNVDLSLVVECMDHALTSLFPKTRYAAGKDAKTFWIPLSHMPAV
LQDFLLLKQKVELANPRAV
|
| External Links |
|---|
| GenBank ID Protein
| AAN75756.1 |
| UniProtKB/Swiss-Prot ID
| Q8HYR6 |
| UniProtKB/Swiss-Prot Entry Name
| DHRS9_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF362071 |
| GeneCard ID
| DHRS9 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
