| Identification |
|---|
| BMDB Protein ID
| BMDBP01029 |
| Secondary Accession Numbers
| None |
| Name
| Prostaglandin reductase 2 |
| Synonyms
|
Not Available
|
| Gene Name
| PTGR2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in 15-oxoprostaglandin 13-oxidase activity |
| Specific Function
| Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 10 |
| Locus
| Not Available |
| SNPs
| PTGR2 |
| Gene Sequence
|
>1056 bp
ATGATTGTACAAAGAGTGGTATTGAATTCCAGACCTGGAAAAAATGGTCATCCAGTGGCA
GAAAATTTCCGAGTAGAAGAAGTAAACTTACCAGATTGTGTCAATGAAGGACAAGTACAA
GTCAGAACTCTTTATCTTTCCGTGGATCCTTACATGCGTTGTAGAATGAATGAAGACACT
GGCAGTGACTATATAACACCTTGGCAGCTGTCTCAGGTGGTTGATGGTGGAGGTGTTGGG
ATTATAGAAGAAAGCAAACACACAAATTTTATGAAAGGTGATTTTGTGACTTCCTTCTAT
TGGCCCTGGCAAACCAAGGTTATTCTGGATGGAAATATCCTTGAAAAGGTAGACCCACAA
CTTGTGGATGGACACCTTTCATATTTTCTTGGAGCTATAGGGATGCCTGGTTTGACTTCC
TTGATTGGGGTACAGGAAAAAGGTCATATAACTGCTGGATCTAATCAGACAATGGTTGTT
AGTGGGGCTGCTGGTGCTTGTGGATCCTTGGCTGGGCAGATTGGCCGTTTGCTGGGCTGT
TCGAGAGTCGTGGGAATTTGTGGAACACCTGAGAAGTGCCTCTTTTTGACCTCAGAATTG
GGCTTCGATGCTGCAATTAATTATAAAGAGGGGAATGTTGCAGAACAACTCCATAAATTA
TGCCCAGCTGGAGTGGATGTTTACTTCGACAATGTTGGCGGTGACATCAGTGATACAGTG
ATAAGTCAGATGAATCAGAACAGCCACATCATCCTATGTGGTCAAATTTCTCAGTACAAC
AAAGATGTGCCTTATCCTCCTCCACTACCCCCTGCTATAGAAGCAATCCAGAAAGAAAGA
AACATCACAAGAGAAAGATTTCTGGTGTTAAATTATAAGGATAAATTTGAGTTTGGTATT
CTCCAACTGAGTCAGTGGTTTAAAGAAGGAAAGCTAAAGATCAAAGAGACTATGATAAAT
GGATTGGAAAACATGGGAGCTGCATTCCAGTCCATGATGACAGGAGGTAACATCGGAAAG
CAGATAGTTTGCATTTCAGGAGATACTTCTTTGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 351 |
| Molecular Weight
| 38400.0 |
| Theoretical pI
| 5.2 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Prostaglandin reductase 2
MIVQRVVLNSRPGKNGHPVAENFRVEEVNLPDCVNEGQVQVRTLYLSVDPYMRCRMNEDT
GSDYITPWQLSQVVDGGGVGIIEESKHTNFMKGDFVTSFYWPWQTKVILDGNILEKVDPQ
LVDGHLSYFLGAIGMPGLTSLIGVQEKGHITAGSNQTMVVSGAAGACGSLAGQIGRLLGC
SRVVGICGTPEKCLFLTSELGFDAAINYKEGNVAEQLHKLCPAGVDVYFDNVGGDISDTV
ISQMNQNSHIILCGQISQYNKDVPYPPPLPPAIEAIQKERNITRERFLVLNYKDKFEFGI
LQLSQWFKEGKLKIKETMINGLENMGAAFQSMMTGGNIGKQIVCISGDTSL
|
| External Links |
|---|
| GenBank ID Protein
| AAI09689.1 |
| UniProtKB/Swiss-Prot ID
| Q32L99 |
| UniProtKB/Swiss-Prot Entry Name
| PTGR2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC109688 |
| GeneCard ID
| PTGR2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
