Showing Protein A disintegrin and metalloproteinase with thrombospondin motifs 5 (BMDBP01037)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01037 |
| Secondary Accession Numbers | None |
| Name | A disintegrin and metalloproteinase with thrombospondin motifs 5 |
| Synonyms | Not Available |
| Gene Name | ADAMTS5 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in metalloendopeptidase activity |
| Specific Function | Cleaves aggrecan, a cartilage proteoglycan, at the '392-Glu-|-Ala-393' site, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 1 |
| Locus | Not Available |
| SNPs | ADAMTS5 |
| Gene Sequence | Not Available |
| Protein Properties | |
| Number of Residues | 207 |
| Molecular Weight | 22576.0 |
| Theoretical pI | 8.05 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>A disintegrin and metalloproteinase with thrombospondin motifs 5 HAAFTVAHEIGHLLGLSHDDSKFCEENFGSTEDKRLMSSILTSIDASKPWSKCTSATITE FLDDGHGNCLLDLPRKQIPGPEELPGQTYDASQQCNLTFGPEYSVCPGMDVCARLWCAVV RQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRS CGGGVQFAYRHCNNPAPKNNGRYCTGK |
| External Links | |
| GenBank ID Protein | AAF07177.1 |
| UniProtKB/Swiss-Prot ID | Q9TT92 |
| UniProtKB/Swiss-Prot Entry Name | ATS5_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | AF192771 |
| GeneCard ID | ADAMTS5 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |