| Identification |
|---|
| BMDB Protein ID
| BMDBP01056 |
| Secondary Accession Numbers
| None |
| Name
| Probable C->U-editing enzyme APOBEC-2 |
| Synonyms
|
Not Available
|
| Gene Name
| APOBEC2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in hydrolase activity, acting on carbon-nitrog |
| Specific Function
| Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 23 |
| Locus
| Not Available |
| SNPs
| APOBEC2 |
| Gene Sequence
|
>675 bp
ATGGCTCAGAAAGAAGAGGCCGCGGCGGCGGCGGAGCCCGCCTCCCAGAATGGCGAGGAG
GTGGAGAACCTAGAGGACCCCGAAAAGCTGAAGGAGCTGATTGAGCTGCCGCCCTTTGAG
ATCGTCACTGGGGAGCGACTGCCTGCCCACTACTTTAAGTTTCAGTTCCGGAATGTGGAG
TACAGCTCCGGCAGGAACAAGACCTTCCTCTGCTATGTGGTGGAAGCGCAGAGCAAGGGA
GGCCAAGTGCAGGCCTCTCGGGGGTACCTGGAGGATGAGCACGCCACTAACCACGCGGAG
GAAGCCTTCTTCAACAGCATCATGCCGACCTTCGACCCCGCCCTGCGCTACATGGTCACC
TGGTACGTGTCCTCCAGTCCCTGCGCGGCCTGCGCGGACCGCATCGTCAAGACCCTCAAT
AAGACCAAGAACCTGCGCCTGCTCATCCTGGTGGGGCGGCTGTTCATGTGGGAAGAGCCT
GAGATACAGGCCGCTCTCAGGAAGCTGAAGGAAGCCGGCTGCAGACTTCGCATCATGAAG
CCCCAGGACTTCGAGTACATCTGGCAGAATTTCGTGGAGCAAGAAGAGGGTGAATCCAAG
GCCTTTGAGCCCTGGGAGGACATTCAGGAGAACTTCCTGTACTATGAGGAGAAGTTGGCG
GACATCCTGAAGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 224 |
| Molecular Weight
| 25962.0 |
| Theoretical pI
| 4.53 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Probable C->U-editing enzyme APOBEC-2
MAQKEEAAAAAEPASQNGEEVENLEDPEKLKELIELPPFEIVTGERLPAHYFKFQFRNVE
YSSGRNKTFLCYVVEAQSKGGQVQASRGYLEDEHATNHAEEAFFNSIMPTFDPALRYMVT
WYVSSSPCAACADRIVKTLNKTKNLRLLILVGRLFMWEEPEIQAALRKLKEAGCRLRIMK
PQDFEYIWQNFVEQEEGESKAFEPWEDIQENFLYYEEKLADILK
|
| External Links |
|---|
| GenBank ID Protein
| ABB90107.1 |
| UniProtKB/Swiss-Prot ID
| Q3SYR3 |
| UniProtKB/Swiss-Prot Entry Name
| ABEC2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| DQ280381 |
| GeneCard ID
| APOBEC2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
