| Identification |
|---|
| BMDB Protein ID
| BMDBP01106 |
| Secondary Accession Numbers
| None |
| Name
| Mannose-6-phosphate isomerase |
| Synonyms
|
Not Available
|
| Gene Name
| MPI |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. |
| Pathways
|
- Alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2
- Fructose and Mannose Degradation
- GDP-alpha-D-mannose biosynthesis
- Nucleotide-sugar biosynthesis
|
| Reactions
|
| Mannose 6-phosphate → Fructose 6-phosphate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 21 |
| Locus
| Not Available |
| SNPs
| MPI |
| Gene Sequence
|
>1272 bp
ATGGCCGCTCAGCGAGTATTCCCACTTTCCTGTGTAGTGCAGCAATATGCCTGGGGAAAG
ATGGGTTCCAACAGTGAAGTGGCCCGGCTGCTGGCCAGCAGTGACCCACTGGCCCAGATC
TCAGAGGACAGACCATATGCAGAGCTGTGGATGGGGACGCACCCCCGGGGAGATGCCAAG
ATCCTTGACAACCGCATCTCGCAGAAGACCCTAGGCCAGTGGATTGCTGATAATCAGGAC
AGCTTGGGTTCGAAGGTCAAGGACACCTTTAACGGCAAACTGCCCTTCCTCTTCAAAGTG
CTTTCAGTTGAAACGGCCCTGTCCATCCAGGCACACCCGAACAAGGAGCTGGCAGAGAAG
CTGCACCTCCAGGCTCCACAGCACTACCCCGATGCCAACCATAAGCCAGAGATGGCAATT
GCCCTCACCCCCTTCCAGGGCTTATGTGGCTTCCGGCCAGTTGAAGAAATTGTGACCTTT
CTAACAAAGGTGCCGGAATTCCAGTTTCTAATTGGAGACAACGCAGCAGCGCAGCTGAAG
CAGAGCCTGAGCCAGGACTCCGAGGCTGTGACTTCTGCTCTGCGGAGCTGTTTCTCCCAC
CTGATGAAGAGCGAGAAGAAGGTGGTGGTGGAGCAGCTGAACCTGTTGGTGAAGCGGATC
TCGCAGCAAGTGGCTGCTGGAAACAACATGGAGGACATCTGTGGGGAGCTCCTGCTGCAG
CTGCACCAGCAGTACCCGGGTGATATCGGATGCTTTGCCATCTACTTCCTGAATCTGCTT
ACCCTGAAGCCGGGGGAGGCCATGTTTCTGGAGGCTAACGTGCCCCATGCCTACCTGAAA
GGAGACTGCGTGGAGTGCATGGCATGTTCAGACAACACAGTGCGTGCTGGCCTGACACCC
AAGTTCATCGATGTGCCAACTCTGTGTGAAATGCTCAGCTACACCCCCAGCCCCAGCCAG
GACAGGCTCTTCCCTCCAGCACGGAGCCCGGAAGACCCCTACCTCTCTATCTATGATCCC
CCTGTGCCAGACTTCACCGTTATGAAGGTGGAGGTACCTGGCTCTGTCACTGAATACAAG
GTCTTGGCCCTGGACTCTGCCAGCATCCTCCTGGTGGTGCAGGGGACAGTGACAGCCAGC
AGCCCCACAGCCCAGGCAGCAATCCCCCTGAAACGTGGTGGGGTGCTCTTCATTGGGGCC
AACGAGAGTGTCTCACTGAAGCTCACTGTGCCTAAGGACCTGCTGATGTTCCGTGCCTGC
TGCCTGCTGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 423 |
| Molecular Weight
| 46369.0 |
| Theoretical pI
| 5.88 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Mannose-6-phosphate isomerase
MAAQRVFPLSCVVQQYAWGKMGSNSEVARLLASSDPLAQISEDRPYAELWMGTHPRGDAK
ILDNRISQKTLGQWIADNQDSLGSKVKDTFNGKLPFLFKVLSVETALSIQAHPNKELAEK
LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLTKVPEFQFLIGDNAAAQLK
QSLSQDSEAVTSALRSCFSHLMKSEKKVVVEQLNLLVKRISQQVAAGNNMEDICGELLLQ
LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP
KFIDVPTLCEMLSYTPSPSQDRLFPPARSPEDPYLSIYDPPVPDFTVMKVEVPGSVTEYK
VLALDSASILLVVQGTVTASSPTAQAAIPLKRGGVLFIGANESVSLKLTVPKDLLMFRAC
CLL
|
| External Links |
|---|
| GenBank ID Protein
| AAI02845.1 |
| UniProtKB/Swiss-Prot ID
| Q3SZI0 |
| UniProtKB/Swiss-Prot Entry Name
| MPI_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC102844 |
| GeneCard ID
| MPI |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
