| Identification |
|---|
| BMDB Protein ID
| BMDBP01110 |
| Secondary Accession Numbers
| None |
| Name
| Poly(A) RNA polymerase GLD2 |
| Synonyms
|
Not Available
|
| Gene Name
| TENT2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ATP binding |
| Specific Function
| Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation. Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 10 |
| Locus
| Not Available |
| SNPs
| TENT2 |
| Gene Sequence
|
>492 bp
ATGTTCCCAAACTCAATTTTGGGTCGCCCGCCTTTCACTCCAAACCATCAACAACATAAT
AACTTCTTTGCCCTGTCACCAAGTCTTTACTCACACCAGCAGCTTATAGATGCACAGTTC
AGCTTTCACAATGCAGACTTGTCTAGAGCTGTGTCATTACAACAGTTGACGTATGGAAAT
GTCAGTCCAATACAGACCTCAACTTCCCCATTATTTCGAGGAAGGAAGAGATTAAGCGAT
GAAAAGAATCTTCCTCTTGATGGTAAACGGCAGCGTTTTCATTCACCCCACCAAGAGCCA
ACTATAGTTAACCACATAGTGCCTTTATCAGATGAAAGAAGATACTCAATGTCACCATTG
TTTCATACACACTATGTACCAGATATAGTCAGATGTGTTCCACCTTTTCGAGAAATATCA
ATTTTAGAACCTAGAGAAATCACACTGCCTGAGGCCAAAGATAAGCTGAATAAGAGGACA
CTTACCTGGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 484 |
| Molecular Weight
| 56051.0 |
| Theoretical pI
| 9.57 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Poly(A) RNA polymerase GLD2
MFPNSILGRPPFTPNHQQHNNFFALSPSLYSHQQLIDAQFSFHNADLSRAVSLQQLTYGN
VSPIQTSTSPLFRGRKRLSDEKNLPLDGKRQRFHSPHQEPTIVNHIVPLSDERRYSMSPL
FHTHYVPDIVRCVPPFREISILEPREITLPEAKDKLSQQILELFEACQQQVSDLKKKELC
RTELQREIQLLFPQSRLFLVGSSLNGFGTRSSDGDLCLVVKEEPCFFQVNQKTEARHILT
LVHKHFCTRLSGYIERPQLIRAKVPIVKFRDKVSCVEFDLNVNNIVGIRNTFLLRTYAYL
ENRVRPLVLVIKKWASHHDINDASRGTLSSYSLVLMVLHYLQTLPEPILPSIQKIYPESF
SPSIQLHLVHQAPCNVPPYLSKNESNLGDLLLGFLKYYATEFDWNSQMISVREAKAIPRP
DGIEWRNKYICVEEPFDGTNTARAVHEKQKFDMIKDQFLKSWHRLKNRKDLNSILPLRAA
ILKR
|
| External Links |
|---|
| GenBank ID Protein
| ABF57350.1 |
| UniProtKB/Swiss-Prot ID
| Q2HJ44 |
| UniProtKB/Swiss-Prot Entry Name
| GLD2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT025394 |
| GeneCard ID
| TENT2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
