Showing Protein Poly(A) polymerase alpha (BMDBP01115)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01115 |
| Secondary Accession Numbers | None |
| Name | Poly(A) polymerase alpha |
| Synonyms | Not Available |
| Gene Name | PAPOLA |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in ATP binding |
| Specific Function | Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 21 |
| Locus | Not Available |
| SNPs | PAPOLA |
| Gene Sequence |
>2220 bp ATGCCGTTTCCAGTTACAACACAGGGATCACAGCAAACACAGCCGCCACAGAAGCACTAT GGCATTACTTCTCCCATCAGCTTAGCAGCCCCCAAGGAGACTGACTGCCTGCTCACACAG AAGCTGGTGGAGACTCTGAAGCCCTTCGGGGTTTTTGAAGAGGAAGAGGAACTGCAGCGC AGGATTTTAATTTTGGGAAAATTAAATAACCTGGTAAAAGAGTGGATACGAGAAATCAGT GAAAGCAAGAATCTTCCACAATCTGTAATTGAAAATGTTGGTGGGAAAATTTTTACATTT GGATCTTATAGATTAGGAGTACATACAAAAGGTGCTGATATTGATGCATTGTGTGTTGCA CCAAGACATGTTGATCGAAGTGATTTTTTCACCTCATTCTATGATAAGTTGAAATTACAG GAAGAAGTAAAAGATTTAAGAGCTGTTGAAGAGGCATTTGTACCAGTTATCAAACTGTGT TTTGATGGGATAGAGATTGATATTTTGTTTGCAAGATTAGCACTGCAGACTATTCCAGAA GACTTGGACTTAAGAGATGACAGTCTGCTTAAAAATTTAGATATAAGATGTATAAGAAGT CTTAACGGTTGCAGGGTAACCGATGAAATTTTACATCTAGTACCAAACATTGACAACTTC AGGTTAACCCTGAGAGCTATCAAACTGTGGGCCAAACGCCACAACATCTATTCCAATATA TTAGGTTTCCTCGGTGGTGTTTCCTGGGCTATGCTAGTAGCAAGAACTTGCCAGCTTTAT CCAAATGCAATAGCATCAACTCTTGTACATAAATTTTTCTTGGTATTTTCTAAATGGGAA TGGCCAAATCCAGTCCTATTGAAACAGCCTGAAGAATGCAATCTTAATTTGCCTGTATGG GACCCAAGGGTAAACCCCAGTGATAGGTACCATCTTATGCCTATAATTACACCAGCATAC CCACAACAGAACTCCACGTACAATGTGTCCGTTTCAACACGGATGGTCATGGTTGAGGAG TTTAAACAAGGTCTTGCTATCACAGATGAAATTTTGCTGAGTAAGGCAGAGTGGTCCAAA CTTTTTGAAGCTCCAAACTTCTTTCAAAAGTACAAGCATTATATTGTACTTCTAGCAAGT GCACCAACTGAAAAACAACGCCTAGAATGGGTGGGCTTGGTGGAATCAAAAATCCGAATC CTGGTTGGAAGTTTGGAGAAGAATGAGTTTATTACACTGGCTCATGTGAATCCCCAGTCA TTTCCAGCACCCAAAGAAAATCCCGACAAGGAAGAATTTCGCACTATGTGGGTGATTGGG TTAGTGTTTAAAAAAACAGAAAACTCTGAAAATCTCAGTGTTGATCTCACCTATGATATT CAGTCTTTCACAGATACAGTTTATAGGCAAGCAATAAACAGCAAGATGTTTGAGGTGGAC ATGAAAATTGCTGCGATGCATGTAAAAAGAAAGCAACTCCATCAACTACTGCCTAGTCAT GTGCTTCAGAAAAAGAAAAAGCATTCAACAGAAGGCGTCAAGTTGACACCTCTGAATGAT AGCAGCCTCGACTTGTCTATGGACAGTGACAACAGCATGTCTGTGCCTTCACCTACTAGT GCTATGAAGACCAGTCCGTTGAACAGTTCTGGCAGCTCTCAGGGCAGAAACAGTCCTGCT CCAGCTGTAACAGCAGCATCTGTGACCAACATACAGGCTACTGAAGTTTCTCTGCCACAA ATAAATTCCAGTGAAAGCTCAGGGGGTACATCGAGTGAAAGCATTCCTCAAACTGCCACA CAACCAGCCATTTCATCACCGCCAAAGCCTACGGTCTCCAGAGTTGTTTCCTCAACACGT TTGGTAAACCCACCACCAAGACCTTCAGGAAATGCAGCAGCAAAGATACCTAATCCTATA GTAGGAGTCAAGAGGACATCCTCACCTCATAAAGAAGAGAGCCCCAAGAAAACCAAAACA GAAGAGGATGAAACAAGTGAAGATGCTAACTGTCTTGCTTTGAGTGGACATGATAAAACA GAAACAAAGGAACAACTTGATACAGAGACAAGTACAACTCAATCAGAAACCATTCAGACA GCGACTTCTCTGTTGGCCTCTCAGAAAACATCCAGTACAGACCTTTCTGATATCCCTGCT CTCCCTGCAAACCCTATTCCTGTTATCAAGAATTCAATAAAACTGAGATTGAATCGGTAA |
| Protein Properties | |
| Number of Residues | 739 |
| Molecular Weight | 82441.0 |
| Theoretical pI | 7.4 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Poly(A) polymerase alpha MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCLLTQKLVETLKPFGVFEEEEELQR RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNI LGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVW DPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSK LFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS FPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVD MKIAAMHVKRKQLHQLLPSHVLQKKKKHSTEGVKLTPLNDSSLDLSMDSDNSMSVPSPTS AMKTSPLNSSGSSQGRNSPAPAVTAASVTNIQATEVSLPQINSSESSGGTSSESIPQTAT QPAISSPPKPTVSRVVSSTRLVNPPPRPSGNAAAKIPNPIVGVKRTSSPHKEESPKKTKT EEDETSEDANCLALSGHDKTETKEQLDTETSTTQSETIQTATSLLASQKTSSTDLSDIPA LPANPIPVIKNSIKLRLNR |
| External Links | |
| GenBank ID Protein | CAA43782.1 |
| UniProtKB/Swiss-Prot ID | P25500 |
| UniProtKB/Swiss-Prot Entry Name | PAPOA_BOVIN |
| PDB IDs | |
| GenBank Gene ID | X61585 |
| GeneCard ID | PAPOLA |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |