| Identification |
|---|
| BMDB Protein ID
| BMDBP01118 |
| Secondary Accession Numbers
| None |
| Name
| DNA polymerase epsilon subunit 3 |
| Synonyms
|
Not Available
|
| Gene Name
| POLE3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Chromatin structure and dynamics |
| Specific Function
| Accessory component of the DNA polymerase epsilon complex (By similarity). Participates in DNA repair and in chromosomal DNA replication (By similarity). Forms a complex with CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1 (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 8 |
| Locus
| Not Available |
| SNPs
| POLE3 |
| Gene Sequence
|
>444 bp
ATGGCGGAGAGGCCCGAGGACTTAAACCTGCCCAATGCCGTCATCACCAGAATCATCAAG
GAGGCGCTCCCGGACGGTGTCAACATCTCCAAGGAGGCCCGGAGCGCCATCTCCCGCGCC
GCCAGCGTCTTCGTGCTGTACGCCACATCCTGTGCCAACAACTTTGCGATGAAAGGGAAA
CGCAAGACACTGAATGCCAGCGATGTGCTGTCAGCCATGGAGGAGATGGAGTTTCAGCGG
TTCGTAACCCCGTTAAAAGAAGCTCTGGAAGCTTATAGGAGGGAGCAAAAAGGCAAGAAG
GAAGCTTCAGAGCAAAAGAAGAAGGACAAAGACAAAAAAACAGATTCGGAAGAGCAGGAC
AAGAGCAGGGATGAGGACAATGATGAAGACGAGGAAAGGCTGGAGGAAGAAGAACAGAAT
GAAGAGGAGGAAGTGGACAACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 147 |
| Molecular Weight
| 16860.0 |
| Theoretical pI
| 4.38 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>DNA polymerase epsilon subunit 3
MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGK
RKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQD
KSRDEDNDEDEERLEEEEQNEEEEVDN
|
| External Links |
|---|
| GenBank ID Protein
| ABQ13017.1 |
| UniProtKB/Swiss-Prot ID
| Q3SZN5 |
| UniProtKB/Swiss-Prot Entry Name
| DPOE3_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT030577 |
| GeneCard ID
| POLE3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
