| Identification |
|---|
| BMDB Protein ID
| BMDBP01156 |
| Secondary Accession Numbers
| None |
| Name
| Adenylate kinase 2, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| AK2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Nucleotide transport and metabolism |
| Specific Function
| Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 2 |
| Locus
| Not Available |
| SNPs
| AK2 |
| Gene Sequence
|
>726 bp
EAMOFAVAIISITE.GGCGGCCATGGCTCCCAACGTGCCTGCGGCCGAACCGGTCCCGGA
GTCTCCTAAAGGCGTCCGGGCCGTGCTCTTAGGGCCGCCCGGAGCCGGCAAGGGTACCCA
GGCACCCAAATTGGCTAAAAACTTCTGTGTCTGCCATTTGGCTACCGGAGACATGCTGAG
GGCCATGGTGGCTTCCGGCTCAGAGCTGGGAAAGAAGCTGAAGGCGACTATGGATGCCGG
GAAGCTGGTGAGTGATGAAATGGTCTTGGAGCTCATTGAAAAGAATTTGGAGACCCCTCC
ATGCAAAAATGGTTTTCTTCTGGATGGCTTCCCTCGGACCGTGAGGCAGGCAGAAATGCT
TGATGACCTCATGGAGAAGAGGAAAGAGAAGCTTGATTCTGTGATTGAATTCAGCATCCC
AGACTCTCTGCTCATCCGGAGAATCACAGGAAGACTGATTCACCCCCAGAGTGGCCGCTC
CTACCACGAGGAGTTCAATCCCCCAAAGGAACCCATGAAAGATGATATCACTGGGGAACC
GTTGATCCGCCGATCAGATGATAATAAGAAGGCCTTGAAAATCCGCCTGGAAGCCTACCA
CACTCAAACCACCCCGCTGGTGGAGTACTACAGTAAACGGGGGATCCACTCCGCCATCGA
TGCGTCCCAGACCCCTGACGTCGTGTTTGCAAGCATCCTAGCAGCATTCTCCAAAGCCAC
ATGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 241 |
| Molecular Weight
| 26497.0 |
| Theoretical pI
| 8.32 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Adenylate kinase 2, mitochondrial
MAPNVPAAEPVPESPKGVRAVLLGPPGAGKGTQAPKLAKNFCVCHLATGDMLRAMVASGS
ELGKKLKATMDAGKLVSDEMVLELIEKNLETPPCKNGFLLDGFPRTVRQAEMLDDLMEKR
KEKLDSVIEFSIPDSLLIRRITGRLIHPQSGRSYHEEFNPPKEPMKDDITGEPLIRRSDD
NKKALKIRLEAYHTQTTPLVEYYSKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMF
I
|
| External Links |
|---|
| GenBank ID Protein
| AAA30364.1 |
| UniProtKB/Swiss-Prot ID
| P08166 |
| UniProtKB/Swiss-Prot Entry Name
| KAD2_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| M16224 |
| GeneCard ID
| AK2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
