| Identification |
|---|
| BMDB Protein ID
| BMDBP01233 |
| Secondary Accession Numbers
| None |
| Name
| M-phase inducer phosphatase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| CDC25A |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein tyrosine phosphatase activity |
| Specific Function
| Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 22 |
| Locus
| Not Available |
| SNPs
| CDC25A |
| Gene Sequence
|
>1578 bp
ATGGAACTGGGCCCGGAGCCCCCGCACCGCCGCCGCCTGCTCTTCGCCTGCAGCCCCCCG
CCCGCACCGCAGCCCGTCGTGAAGGCGCTGTTTGGCACGCCAGCCGCCGGGGGCCTGTCG
CCTGTCACCAACCTGACGGTCACCATGGACCAGCTGCAGGGACTGGGCAGTGAGTATGAA
CAACCCATAGAGGTGAAAAACAGCAGTCTGCAGAGAATGGGCTCCTCCGAATCAACTGAT
TCAGGCTTCTGTCTGGATTCTCCTGGGCCCTTGGATAGTAAAGAAAACCTTGAAAATCCC
ATGAGGAGAATAAATTCCCTACCTCAGAAGCTCTTGGGGTGTAGCCCAGCTCTGAAGAGG
AGCCATTCTGATTCTCTTGACCATGATGTCTTTCAGCTGATTGACCAGGATGAGAACAAG
GAAAATCAAGTCTTTGAGTTTAAGAAGCCAATAAGACCTGCATCTCGAGGCTGCCTACAT
GTTCACGGACTGGAGGAGGGTAAAGATGTCTTCACACAGAGGCAGAACTCCGCCCCAGCT
CGGATGCTTTCCTCAAATGAAAGAGATGGCAATGAACCAGGGAATTCCATTCCTTTTATG
CCCCAGTCACCTGTGACTCCCACTTTGTCTGATGAGGATGATGGCTTCATGGATCTTCTT
GATGGAGAGAATTTGAAGAATGATGAAGAGACCCCATCCTGCATGGCCAGCCTCTGGACA
GCTCCCCTTGTCATGAGAAGAACTAATAACCTAGGCAATCGCTGCAAGCTGTTTGACTCC
CCTTCAGCGTCGTGTAGCTCTACCATCCGGTCAATGTTGAAAAGACCAGACCGATCACTA
GAGGAGTCCCCAGGTGGAAGCAGGAAGCGGAGGAAAAGCGTGGCTGGGGCCAGTCCGGAA
GAGGCAGCTAGTCCAGAGAAGCCCCAGGAGATTCTACATCATCAGTCTTTATCCCTAGCA
TCTTCCCCAAAAGGGACCATTGAGAACATTTTGGATAATGACCCAAGGGACCTTATAGGA
GACTTCTCCAAGGGTTACCTCTTTCATACCGTTGCTGGAAAGCATCAGGATTTAAAATAC
ATCTCTCCAGAAATTATTACATCTGTTTTGAATGGCAAGTTTGCCAACCTCATTAAAGAG
TTTGTCATCATCGACTGCCGATACCCATATGAATATGAGGGAGGCCACATCAAGGGTGCA
GTGAACTTGCACATGGAAGAGGAGGTTGAAGAGTTCTTACTCAAGAAGCCTATCGTACCT
ACGGATGGCAAGCGTGTTATCGTGGTGTTCCACTGCGAGTTCTCTTCTGAGCGCGGCCCT
CGCATGTGCCGATACGTGAGAGAGAGGGATCGGCTCGGTAACGAGTACCCCAAACTCCAC
TACCCAGAGCTGTATGTCCTGAAGGGCGGATACAAGGAGTTCTTCCTGAAATGCCAGTCT
CACTGCGAGCCCCCCAGCTACCGGCCCATGCACCACGAGGACTTTAAAGAAGACCTGAAG
AAATTCCGCACCAAGAGCCGGACCTGGGCCGGGGAGAAGAGCAAGAGGGAGATGTACAGC
CGCCTGAAGAAGCTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 525 |
| Molecular Weight
| 59142.0 |
| Theoretical pI
| 7.07 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>M-phase inducer phosphatase 1
MELGPEPPHRRRLLFACSPPPAPQPVVKALFGTPAAGGLSPVTNLTVTMDQLQGLGSEYE
QPIEVKNSSLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRINSLPQKLLGCSPALKR
SHSDSLDHDVFQLIDQDENKENQVFEFKKPIRPASRGCLHVHGLEEGKDVFTQRQNSAPA
RMLSSNERDGNEPGNSIPFMPQSPVTPTLSDEDDGFMDLLDGENLKNDEETPSCMASLWT
APLVMRRTNNLGNRCKLFDSPSASCSSTIRSMLKRPDRSLEESPGGSRKRRKSVAGASPE
EAASPEKPQEILHHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKY
ISPEIITSVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEEFLLKKPIVP
TDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFLKCQS
HCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
|
| External Links |
|---|
| GenBank ID Protein
| AAI51494.1 |
| UniProtKB/Swiss-Prot ID
| A7MBD1 |
| UniProtKB/Swiss-Prot Entry Name
| MPIP1_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC151493 |
| GeneCard ID
| CDC25A |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
