| Identification |
|---|
| BMDB Protein ID
| BMDBP01253 |
| Secondary Accession Numbers
| None |
| Name
| Uricase |
| Synonyms
|
Not Available
|
| Gene Name
| UOX |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Secondary metabolites biosynthesis, transport and catabolism |
| Specific Function
| Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. |
| Pathways
|
- (S)-allantoin from urate: step 1/3
- Purine Metabolism
- Urate degradation
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| Not Available |
| SNPs
| UOX |
| Gene Sequence
|
>915 bp
ATGGCTCATTACCATAATGACTATCAAAAGAATGATGAAGTGGAGTTTGTCCGAACTGGT
TATGGTAAGGATATGGTAAAAGTTCTTCATATTCAGCGGGATGGAAAATACCACAGCATT
AAGGAAGTGGCAACTTCAGTGCAACTTACTCTAAACTCCAGAAGAGAGTACCTGCATGGA
GACAATTCAGACATCATCCCGACAGACACCATCAAGAACACAGTTCAAGTCCTGGCCAAG
TTCAAAGGCATCAAAAGCATAGAAACTTTTGCTATGAATATCTGTGAGCATTTCCTTTCT
TCTTTTAACCACGTCATTCGAGTTCAAGTCTACGTGGAAGAAGTCCCTTGGAAGCGTTTT
GAAAAGAATGGAGTTAAGCACGTCCATGCATTTATTCATACTCCCACTGGAACGCATTTC
TGTGAGGTTGAACAGTTGAGGAGTGGACCTCCAGTCATTCATTCTGGAATCAAAGACCTC
AAGGTCCTGAAAACAACGCAGTCTGGATTTGAAGGATTCCTCAAGGATCAGTTCACCACC
CTCCCTGAGGTGAAGGACCGGTGCTTTGCTACCCAAGTGTACTGCAAATGGCGCTACCAC
CAGGGCAGAGATGTGGACTTTGAGGCCACCTGGGAGGCTGTCAGGGGCATTGTCCTGAAG
AAGTTCGCTGGACCCTATGACAAAGGCGAGTACTCGCCCTCAGTCCAGAAGACCCTCTAT
GACATCCAGGTGCTCTCCCTGAGCCAGCTTCCTGAGATAGAAGATATGGAAATCAGTCTG
CCGAACATTCACTACTTTAACATAGACATGTCCAAAATGGGACTGATCAACAAGGAAGAG
GTCTTGTTACCATTAGACAATCCATATGGCAGAATTACTGGTACAGTCAAGAGGAAGCTG
ACTTCAAGGCTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 304 |
| Molecular Weight
| 35124.0 |
| Theoretical pI
| 8.31 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Uricase
MAHYHNDYQKNDEVEFVRTGYGKDMVKVLHIQRDGKYHSIKEVATSVQLTLNSRREYLHG
DNSDIIPTDTIKNTVQVLAKFKGIKSIETFAMNICEHFLSSFNHVIRVQVYVEEVPWKRF
EKNGVKHVHAFIHTPTGTHFCEVEQLRSGPPVIHSGIKDLKVLKTTQSGFEGFLKDQFTT
LPEVKDRCFATQVYCKWRYHQGRDVDFEATWEAVRGIVLKKFAGPYDKGEYSPSVQKTLY
DIQVLSLSQLPEIEDMEISLPNIHYFNIDMSKMGLINKEEVLLPLDNPYGRITGTVKRKL
TSRL
|
| External Links |
|---|
| GenBank ID Protein
| AAI05245.1 |
| UniProtKB/Swiss-Prot ID
| Q3MHG7 |
| UniProtKB/Swiss-Prot Entry Name
| URIC_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC105244 |
| GeneCard ID
| UOX |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
