| Identification |
|---|
| BMDB Protein ID
| BMDBP01297 |
| Secondary Accession Numbers
| None |
| Name
| Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 |
| Synonyms
|
Not Available
|
| Gene Name
| GCNT3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in beta-1,3-galactosyl-O-glycosyl-glycoprotein |
| Specific Function
| Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. |
| Pathways
|
- Protein glycosylation
- Protein modification
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 10 |
| Locus
| Not Available |
| SNPs
| GCNT3 |
| Gene Sequence
|
>1323 bp
ATGAAGATGACTGGGTGGAAGAAGAAGCTTTGCCGGGGGCATCATCTGTGGGCTCTGGGC
TGCTATATGCTGCTGGCCGTTGTTGCTCTGAGGCTTTCTCTCAGGTTGAAATGTGATGTA
GATTCCTTGGATCTGGAGTCCAGGGACTTCCAAAGTCAGCGTTGTAGGGACGTCTTGTAC
AAGAACCTGAAGCTGCCAGCAAAGAGATCCATCAACTGTTCTGGGATCACACGAGGGGAC
CAGGAAGCGGTGGTCCAGGCTCTCCTGGACAACCTGGAAGTCAAGAAGAAGCGGTTGCCT
TTCACTGACACCTATTACCTCAACATAACCAGAGACTGTGAGCAGTTTAAGGCCCAAAGG
AAGTTCATACAGTTCCCACTGAGCAAAGAAGAGTTAGACTTCCCCATTGCATACTCGATG
GTGGTCCATGAGAAGATTGAAAACTTTGAACGGCTGCTGCGAGCTGTGTATGCCCCTCAG
AACATATACTGTGTCCATGTGGATGTGAAGTCCCCAGAAACTTTCAAAGAGGCAGTCAAG
GCCATTATTTCCTGCTTCCCCAATGTCTTCATGGCCAGTAAGTTGGTCCCAGTGGTTTAT
GCCTCCTGGTCCAGAGTGCAGGCTGACCTGAACTGTATGGAAGACTTGCTCCAGAGCTCG
GTGCCATGGAAATACTTACTGAATACATGTGGGACAGACTTCCCCATAAAGACCAACGCC
GAGATGGTTCTGGCCCTCAAGATGTTGAATGGGAAGAACAGTATGGAGTCTGAGATACCT
TCTGAGTCCAAAAAAAATCGCTGGAAATACCGCTATGAGGTGACAGACAGACTGTACCTA
ACCAGCAAGATGAAGGACCCTCCCCCTGATAATTTACCTATGTTCACGGGGAATGCCTAT
TTTGTGGCTTCTCGAGCCTTTGTCCAACATGTCTTAGAGAACCCCAAATCCCAAAGACTG
ATTGAATGGGTCAAAGACACCTATAGCCCCGACGAACACCTCTGGGCCACCCTTCAGCGT
GCTCCATGGATGCCTGGCTCTGTTCCTTACCACCCCAAGTATCACATCTCAGACATGACT
GCCATCGCCAGGCTGGTCAAGTGGCAGGGCCACGAGGGAGATGTCAGCATGGGGGCGCCT
TATGCACCCTGCTCTGGAATCCATCAGCGGGCCATCTGCATTTACGGGGCCGGGGACCTG
CACTGGATTCTCCAGAACCATCACCTCTTGGCAAACAAGTTTGACCCAAGGGTGGATGAT
AACGTCCTGCAGTGCTTAGAAGAGTATTTACGTCATAAGGCCATCTATGGGACTGAACTT
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 440 |
| Molecular Weight
| 50953.0 |
| Theoretical pI
| 8.65 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
MKMTGWKKKLCRGHHLWALGCYMLLAVVALRLSLRLKCDVDSLDLESRDFQSQRCRDVLY
KNLKLPAKRSINCSGITRGDQEAVVQALLDNLEVKKKRLPFTDTYYLNITRDCEQFKAQR
KFIQFPLSKEELDFPIAYSMVVHEKIENFERLLRAVYAPQNIYCVHVDVKSPETFKEAVK
AIISCFPNVFMASKLVPVVYASWSRVQADLNCMEDLLQSSVPWKYLLNTCGTDFPIKTNA
EMVLALKMLNGKNSMESEIPSEYKKNRWKYRYEVTDRLYLTSKMKDPPPDNLPMFTGNAY
FVASRAFVQHVLENPKSQRLIEWVKDTYSPDEHLWATLQRAPWMPGSVPYHPKYHISDMT
AIARLVKWQGHEGDVSMGAPYAPCSGIHQRAICIYGAGDLHWILQNHHLLANKFDPRVDD
NVLQCLEEYLRHKAIYGTEL
|
| External Links |
|---|
| GenBank ID Protein
| AAO22165.1 |
| UniProtKB/Swiss-Prot ID
| Q7YQE1 |
| UniProtKB/Swiss-Prot Entry Name
| GCNT3_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF465338 |
| GeneCard ID
| GCNT3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
