1.0 2018-05-07 22:26:20 UTC 2020-05-20 21:05:37 UTC BMDBP01299 Enzyme GUCA1A Involved in calcium ion binding Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevated (PubMed:7520254, PubMed:8626484, PubMed:9651312, PubMed:26703466). This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure (PubMed:7520254, PubMed:8626484). May be involved in cone photoreceptor light response and recovery of response in bright light (By similarity). BMDB0000464 Calcium 23 >618 bp ATGGGGAACATTATGGACGGTAAGTCGGTGGAGGAGCTGAGCAGCACCGAGTGCCACCAG TGGTACAAGAAGTTCATGACAGAGTGCCCCTCCGGCCAGCTCACCCTCTACGAGTTCCGC CAGTTCTTCGGCCTCAAGAACCTGAGCCCGTGGGCCAGCCAGTACGTGGAGCAGATGTTT GAGACCTTTGACTTCAACAAAGACGGCTACATTGATTTCATGGAGTACGTGGCGGCTCTG AGCCTGGTCCTCAAGGGGAAGGTGGAACAGAAGCTGCGTTGGTACTTCAAGCTCTACGAC GTGGACGGCAACGGATGCATCGACCGCGACGAGCTGCTCACCATCATCCGGGCCATCCGA GCCATTAACCCCTGCAGCGACTCGACCATGACCGCCGAGGAGTTCACCGATACAGTGTTC TCCAAGATTGACGTCAATGGGGATGGGGAACTCTCCCTAGAGGAGTTCATGGAGGGCGTC CAGAAGGACCAGATGCTCTTGGACACGCTGACCCGAAGCTTGGACCTTACCCGCATTGTG CGCAGGCTCCAGAATGGAGAGCAGGATGAGGAGGGGGCTAGCGGCAGGGAAACGGAGGCC GCGGAGGCCGACGGCTGA 205 23510.0 4.14 None >Guanylyl cyclase-activating protein 1 MGNIMDGKSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPWASQYVEQMF ETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIR AINPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTLTRSLDLTRIV RRLQNGEQDEEGASGRETEAAEADG AAB31698.2 P46065 GUC1A_BOVIN 2NA0 2NA0 S74247 GUCA1A