1.0 2018-05-07 22:26:29 UTC 2020-05-20 21:06:37 UTC BMDBP01329 Enzyme PFN2 Involved in actin binding Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. BMDB0010032 PIP2(16:0/16:0) BMDB0010033 PIP2(16:0/16:1(9Z)) BMDB0010034 PIP2(16:0/16:2(9Z,12Z)) BMDB0010035 PIP2(16:0/18:0) BMDB0010036 PIP2(16:0/18:1(11Z)) BMDB0010037 PIP2(16:0/18:1(9Z)) BMDB0010038 PIP2(16:0/18:2(9Z,12Z)) BMDB0010039 PIP2(16:0/20:1(11Z)) BMDB0010040 PIP2(16:0/20:2(11Z,14Z)) BMDB0010041 PIP2(16:0/20:3(5Z,8Z,11Z)) BMDB0010042 PIP2(16:0/20:3(8Z,11Z,14Z)) BMDB0010043 PIP2(16:0/20:4(5Z,8Z,11Z,14Z)) BMDB0010044 PIP2(16:0/20:4(8Z,11Z,14Z,17Z)) BMDB0010045 PIP2(16:0/22:2(13Z,16Z)) BMDB0010046 PIP2(16:0/22:3(10Z,13Z,16Z)) BMDB0010047 PIP2(16:0/22:4(10Z,13Z,16Z,19Z)) BMDB0010048 PIP2(16:0/22:4(7Z,10Z,13Z,16Z)) BMDB0010049 PIP2(16:0/22:5(4Z,7Z,10Z,13Z,16Z)) BMDB0010050 PIP2(16:0/22:5(7Z,10Z,13Z,16Z,19Z)) BMDB0010051 PIP2(16:1(9Z)/16:0) BMDB0010052 PIP2(16:1(9Z)/16:1(9Z)) BMDB0010053 PIP2(16:1(9Z)/18:0) BMDB0010054 PIP2(16:1(9Z)/18:1(11Z)) BMDB0010055 PIP2(16:1(9Z)/18:1(9Z)) BMDB0010056 PIP2(16:2(9Z,12Z)/16:0) BMDB0010057 PIP2(16:2(9Z,12Z)/18:0) BMDB0010058 PIP2(16:2(9Z,12Z)/22:3(10Z,13Z,16Z)) BMDB0010059 PIP2(18:0/16:0) BMDB0010060 PIP2(18:0/16:1(9Z)) BMDB0010061 PIP2(18:0/16:2(9Z,12Z)) BMDB0010062 PIP2(18:0/18:1(11Z)) BMDB0010063 PIP2(18:0/18:1(9Z)) BMDB0010064 PIP2(18:0/18:2(9Z,12Z)) BMDB0010065 PIP2(18:0/18:3(6Z,9Z,12Z)) BMDB0010066 PIP2(18:0/18:3(9Z,12Z,15Z)) BMDB0010067 PIP2(18:0/20:2(11Z,14Z)) BMDB0010068 PIP2(18:0/20:3(5Z,8Z,11Z)) BMDB0010069 PIP2(18:0/20:3(8Z,11Z,14Z)) BMDB0010070 PIP2(18:0/20:4(5Z,8Z,11Z,14Z)) BMDB0010071 PIP2(18:0/20:4(8Z,11Z,14Z,17Z)) BMDB0010072 PIP2(18:1(11Z)/16:0) BMDB0010073 PIP2(18:1(11Z)/16:1(9Z)) BMDB0010074 PIP2(18:1(11Z)/18:0) BMDB0010075 PIP2(18:1(11Z)/18:1(11Z)) BMDB0010076 PIP2(18:1(11Z)/18:1(9Z)) BMDB0010077 PIP2(18:1(11Z)/18:2(9Z,12Z)) BMDB0010078 PIP2(18:1(11Z)/18:3(6Z,9Z,12Z)) BMDB0010079 PIP2(18:1(11Z)/18:3(9Z,12Z,15Z)) BMDB0010080 PIP2(18:1(11Z)/20:1(11Z)) BMDB0010081 PIP2(18:1(11Z)/20:3(5Z,8Z,11Z)) BMDB0010082 PIP2(18:1(11Z)/20:3(8Z,11Z,14Z)) BMDB0010083 PIP2(18:1(11Z)/20:4(5Z,8Z,11Z,14Z)) BMDB0010084 PIP2(18:1(11Z)/20:4(8Z,11Z,14Z,17Z)) BMDB0010085 PIP2(18:1(9Z)/16:0) BMDB0010086 PIP2(18:1(9Z)/16:1(9Z)) BMDB0010087 PIP2(18:1(9Z)/18:0) BMDB0010088 PIP2(18:1(9Z)/18:1(11Z)) BMDB0010089 PIP2(18:1(9Z)/18:1(9Z)) BMDB0010090 PIP2(18:1(9Z)/18:2(9Z,12Z)) BMDB0010091 PIP2(18:1(9Z)/18:3(6Z,9Z,12Z)) BMDB0010092 PIP2(18:1(9Z)/18:3(9Z,12Z,15Z)) BMDB0010093 PIP2(18:1(9Z)/20:1(11Z)) BMDB0010094 PIP2(18:1(9Z)/20:3(5Z,8Z,11Z)) BMDB0010095 PIP2(18:1(9Z)/20:3(8Z,11Z,14Z)) BMDB0010096 PIP2(18:1(9Z)/20:4(5Z,8Z,11Z,14Z)) BMDB0010097 PIP2(18:1(9Z)/20:4(8Z,11Z,14Z,17Z)) BMDB0010098 PIP2(18:2(9Z,12Z)/16:0) BMDB0010099 PIP2(18:2(9Z,12Z)/18:0) BMDB0010100 PIP2(18:2(9Z,12Z)/18:1(11Z)) BMDB0010101 PIP2(18:2(9Z,12Z)/18:1(9Z)) BMDB0010102 PIP2(18:2(9Z,12Z)/18:2(9Z,12Z)) BMDB0010103 PIP2(18:2(9Z,12Z)/20:0) BMDB0010104 PIP2(18:2(9Z,12Z)/20:1(11Z)) BMDB0010105 PIP2(18:2(9Z,12Z)/20:2(11Z,14Z)) BMDB0010106 PIP2(18:2(9Z,12Z)/20:3(5Z,8Z,11Z)) BMDB0010107 PIP2(18:2(9Z,12Z)/20:3(8Z,11Z,14Z)) BMDB0010108 PIP2(18:3(6Z,9Z,12Z)/18:0) BMDB0010109 PIP2(18:3(6Z,9Z,12Z)/18:1(11Z)) BMDB0010110 PIP2(18:3(6Z,9Z,12Z)/18:1(9Z)) BMDB0010111 PIP2(18:3(9Z,12Z,15Z)/18:0) BMDB0010112 PIP2(18:3(9Z,12Z,15Z)/18:1(11Z)) BMDB0010113 PIP2(18:3(9Z,12Z,15Z)/18:1(9Z)) BMDB0010114 PIP2(20:0/18:2(9Z,12Z)) BMDB0010115 PIP2(20:1(11Z)/16:0) BMDB0010116 PIP2(20:1(11Z)/18:1(11Z)) BMDB0010117 PIP2(20:1(11Z)/18:1(9Z)) BMDB0010118 PIP2(20:1(11Z)/18:2(9Z,12Z)) BMDB0010119 PIP2(20:2(11Z,14Z)/16:0) BMDB0010120 PIP2(20:2(11Z,14Z)/18:0) BMDB0010121 PIP2(20:2(11Z,14Z)/18:2(9Z,12Z)) BMDB0010122 PIP2(20:3(5Z,8Z,11Z)/16:0) BMDB0010123 PIP2(20:3(5Z,8Z,11Z)/18:0) BMDB0010124 PIP2(20:3(5Z,8Z,11Z)/18:1(11Z)) BMDB0010125 PIP2(20:3(5Z,8Z,11Z)/18:1(9Z)) BMDB0010126 PIP2(20:3(5Z,8Z,11Z)/18:2(9Z,12Z)) BMDB0010127 PIP2(20:3(8Z,11Z,14Z)/16:0) BMDB0010128 PIP2(20:3(8Z,11Z,14Z)/18:0) BMDB0010129 PIP2(20:3(8Z,11Z,14Z)/18:1(11Z)) BMDB0010130 PIP2(20:3(8Z,11Z,14Z)/18:1(9Z)) BMDB0010131 PIP2(20:3(8Z,11Z,14Z)/18:2(9Z,12Z)) BMDB0010132 PIP2(20:4(5Z,8Z,11Z,14Z)/16:0) BMDB0010133 PIP2(20:4(5Z,8Z,11Z,14Z)/18:0) BMDB0010134 PIP2(20:4(5Z,8Z,11Z,14Z)/18:1(11Z)) BMDB0010135 PIP2(20:4(5Z,8Z,11Z,14Z)/18:1(9Z)) BMDB0010136 PIP2(20:4(8Z,11Z,14Z,17Z)/16:0) BMDB0010137 PIP2(20:4(8Z,11Z,14Z,17Z)/18:0) BMDB0010138 PIP2(20:4(8Z,11Z,14Z,17Z)/18:1(11Z)) BMDB0010139 PIP2(20:4(8Z,11Z,14Z,17Z)/18:1(9Z)) BMDB0010140 PIP2(22:2(13Z,16Z)/16:0) BMDB0010141 PIP2(22:3(10Z,13Z,16Z)/16:0) BMDB0010142 PIP2(22:3(10Z,13Z,16Z)/16:2(9Z,12Z)) BMDB0010143 PIP2(22:4(10Z,13Z,16Z,19Z)/16:0) BMDB0010144 PIP2(22:4(7Z,10Z,13Z,16Z)/16:0) BMDB0010145 PIP2(22:5(4Z,7Z,10Z,13Z,16Z)/16:0) BMDB0010146 PIP2(22:5(7Z,10Z,13Z,16Z,19Z)/16:0) 1 >423 bp ATGGCCGGTTGGCAGAGCTACGTGGATAACCTGATGTGCGATGGCTGCTGCCAGGAGGCC GCCATTGTCGGCTACTGCGACGCCAAATACGTCTGGGCAGCCACGGCCGGGGGCGTCTTC CAGAGCATTACGCCAGTAGAAATAGATATGATTGTAGGAAAAGACCGGGAAGGTTTCTTT ACCAATGGTTTGACTCTTGGCGCAAAGAAGTGCTCAGTGATCAGAGATAGCCTATACGTG GACGGTGACTGCACAATGGACATCCGGACAAAGAGTCAAGGTGGGGAGCCAACGTACAAC GTGGCCGTGGGCAGAGCTGGTAGAGTCTTGGTCTTTGTAATGGGAAAAGAAGGGGTCCAT GGAGGCGGATTGAATAAGAAGGCATACTCAATGGCAAAATACTTGAGAGACTCTGGGTTC TAG 140 15032.0 7.04 None >Profilin-2 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPVEIDMIVGKDREGFF TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH GGGLNKKAYSMAKYLRDSGF AAI22617.1 Q09430 PROF2_BOVIN 1D1J BC122616 PFN2