1.0 2018-05-07 22:26:30 UTC 2020-05-20 21:11:47 UTC BMDBP01334 Enzyme ITPR2 Involved in calcium ion binding Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium (PubMed:11584008). This release is regulated by cAMP both dependently and independently of PKA (By similarity). BMDB0000464 Calcium BMDB0001498 Inositol 1,4,5-trisphosphate 5 >8106 bp ATGTCCGATAAAATGTCCAGCTTCCTCTATATAGGGGACATCGTGTCCCTGTACGCGGAG GGTTCGGTCAACGGTTTCATCAACACGCTGGGACTGGTGGATGACCGATGTGTGGTGCAC CCAGAAGCAGGGGACCTTGCCAACCCTCCCAAGAAGTTCCGAGACTGCCTCTTTAAGGTG TGCCCTATGAACCGATATTCTGCTCAGAAGCAATATTGGAAAGCCAAGCAAGCTAAACAA GGGAACCACACAGAGGCGGCCTTGCTGAAGAAATTACAGCATGCTGCAGAACTGGAACAA AAACAAAATGAATCAGAGAATAAGAAGCTATTGGGAGAAATTGTGAAATACAGTAATGTT ATACAACTACTGCATATAAAAAGCAACAAGTATCTGACTGTCAACAAGAGATTACCTGCT TTACTGGAGAAGAATGCCATGCGCGTGTCCTTGGATGCTGCGGGAAATGAAGGGTCTTGG TTTTATATTCATCCCTTCTGGAAGCTGAGAAGCGAGGGCGACAATATTGTTGTTGGAGGT AAAGTTGTTTTGATGCCCGTGAATGCAGGACAGCCACTACATGCCAGCAACATTGAACTA CTCGATAATCCAGGGTGTAAAGAGGTGAATGCTGTTAATTGCAACACTAGCTGGAAAATC ACTTTATTCATGAAATACAGTTCCTATCGAGAAGATGTACTAAAAGGAGGTGATGTTGTT CGCTTGTTCCATGCGGAACAAGAGAAGTTTCTGACTTGTGATGAATATGAGAAAAAGCAG CACATTTTCCTTCGTACAACCTTGCGTCAATCAGCCACTTCTGCAACCAGCTCTAAAGCA CTCTGGGAAATAGAGGTAGTTCATCATGATCCATGCCGTGGGGGTGCAGGACAGTGGAAC AGCTTGTTCAGATTTAAACATCTTGCAACTGGGAACTATTTAGCTGCAGAGCTTAACCCT GATTATCGAGATGCCCAAAATGAAGGAAAAAATGTGAGAGATGGGGATCTTCCAGCTTCA AAGAAGAAACGCCAGGCAGGGGAGAAGATCATGTACACTTTGGTCTCAGTCCCGCATGGA AATGACATTGCGTCGCTTTTCGAACTGGATGCCACGACTCTTCAGAGAGCAGACTGCCTG GTTCCAAGGAACTCATATGTGCGGTTAAGACATCTATGTACAAACACATGGGTAACCAGT ACTAGCATCCCCATAGACACGGATGAAGAGAGGCCTGTTATGTTGAAGATTGGAACTTGC CAGACAAAAGAAGATAAAGAAGCATTTGCCATTGTGTCTGTCCCACCGTCCGAGGTCCGA GATTTAGACTTTGCCAATGATGCAAATAAAGTGCTGGCGACTACAGTTAAAAAGCTGGAA AATGGCACAATAACCCAGAATGAAAGGAGGTTTGTAACCAAGTTACTGGAAGACCTTATC TTCTTTGTTGCTGATGTACCTAACAACGGACAAGACGTTCTAGACGTGCTTATCACCAAG CCAAACCGAGAACGTCAGAAGTTAATGAGGGAACAGAACATATTGGCACAGGTATTTGGG ATTCTTAAAGCACCCTTTAAGGAGAAAGCAGGAGAAGGGTCAATGTTGAGACTGGAAGAT CTGGGGGATCAAAGATATGCCCCCTATAAGTACATGCTGAGGCTGTGCTACCGTGTGCTG GGACATTCGCAGCAGGACTACCGGAAAAATCAGGAATACATTGCTAAGAATTTCTGTGTC ATGCAGTCCCAGATTGGCTATGATATTTTGGCAGAAGATACCATCACAGCTTTGTTGCAC AACAACAGAAAACTACTAGAGAAACACATTACAGCAAAAGAAATAGAAACATTTGTTAGT TTACTCAGGAGAAATCGAGAGCCAAGGTTTTTGGATTATTTATCAGATCTGTGTGTGTCT AATACCACCGCGATACCCGTAACTCAAGAACTCATCTGCAAATTTATGTTGAGCCCAGGC AACGCAGACATTCTCATTCAAACCAAACTGGTCTCAATGCAAGGAGACAACCCCATGGAG AGTGCCATCCTTTCAGATGACATTGATGAGGAAGAAGTTTGGCTCTACTGGATTGACAGC AACAAGGAACCTCATGGCAAAGCCATCAGGCACCTTGCCCAGGAGGCAAAGGAGGGCACC AAGGCCGATTTGGAAGTCCTTACCTATTACAGGTACCAGCTAAATCTCTTTGCAAGGATG TGCTTGGATCGCCAGTATCTGGCCATAAACCAGATTTCTACACAGCTCTCTGTTGATTTG ATCCTGCGATGTATGTCAGATGAGAGCCTGCCTTTTGACCTCCGAGCATCTTTTTGTCGC CTCATGCTCCACATGCATGTTGACCGGGATCCCCAGGAGTCCGTGGTGCCTGTTCGCTAT GCCCGGCTCTGGACAGAAATCCCCACGAAGATCACAATTCATGAATATGATTCTATAACA GACTCTTCCAGAAATGATATGAAGAGGAAATTTGCACTGACAATGGAATTTGTTGAAGAA TACTTGAAAGAAGTTGTAAATCAGCCTTTTCCTTTTGGAGATAAAGAAAAAAACAAACTG ACATTTGAGGTGGTTCACTTGGCTCGGAATCTTATATACTTTGGATTTTACAGTTTCAGT GAATTGTTACGGCTAACAAGGACTCTTCTGGCTATCTTAGATATTGTCCAGGCCCCCATG TCATCATATTTTGAAAGATTAAGCAAATTTCAAGATGGAGGAAACAATGTCATGAGAACC ATCCATGGGGTGGGAGAGATGATGACCCAGATGGTGCTCAGCAGAGGCTCTATCTTCCCC ATGAGTGTGCCTGACATTCAGCCCAGCCTGCACCCCAGCAAGCAGGGGAGCCCCACTGAC CACGAGGACGTCACCGTCATGGACACCAAGCTGAAGATCATTGAGATTTTACAGTTTATC TTGAGTGTCAGACTAGATTATGGGATCTCCTATATGCTGTCAATATATAAGAAGGAATTC GGGGAGAACAACGGAAATGCCGAAATGTCCACCAATGGCTCTCCTGATACACTGCTGCCA TCAGCTATTGTTCCTGATATAGATGAAATTGCAGCTCAGGCAGAAACTATGTTTGCTGGA AGAAAGGAGAAAAATCCAGTTCAACTTGATGACGAAGGAGGCAGGACGTTTTTACGGGTT CTTATTCATCTGATCATGCATGACTACCCGCCTCTGCTATCAGGAGCCCTGCAGCTGCTG TTCAAGCACTTCAGCCAGAGAGCGGAAGTTTTACAGGCATTTAAACAGGTGCAGTTGCTG GTGTCTAATCAGGATGTAGATAACTACAAGCAGATCAAGGCAGATTTAGACCAGCTTCGA CTTACTGTAGAGAAATCGGAGTTATGGGTTGAGAAGAGCAGCAGCTATGAGAATGGAGAA ATGGGTGAAAATCAAGTAAAAGGTGGTGAAGAGCCAATTGAGGACTCAAACATTTTAAGT CCAGTGCAAGATGGAACAAAGAAACCTCAGATTGACAGCAATAAGAGCAACAACTATCGG ATTGTAAAGGAGATTTTGATTAGGCTCAGTAAACTCTGCGTCCAGAACAAAAAGTGTCGC AATCAACATCAACGATTATTGAAAAATATGGGAGCGCATTCGGTGGTGTTGGATCTGCTG CAGATACCCTATGAAAAGAATGATGAGAAGATGAACGAAGTAATGAATCTGGCTCACACA TTCCTGCAGAATTTCTGTCGGGGGAATCCACAGAATCAAGTTCTCCTCCATAAACATCTG AATTTGTTCTTAACCCCTGGTCTCCTTGAAGCAGAAACTATGCGGCACATCTTCATGAAC AATTACCATCTGTGCAATGAAATTAGTGAGAGAGTTGTCCAGCACTTCGTGCACTGCATT GAGACACACGGCCGCCACGTGGAGTACCTGAGGTTTCTGCAGACAATTGTCAAAGCAGAT GGTAAATACGTGAAGAAATGCCAGGATATGGTAATGACCGAGTTGATAAATGGGGGTGAA GATGTGCTGATATTTTACAATGATAGAGCATCATTTCCCATCCTTCTCCATATGATGTGT TCAGAGAGAGACCGAGGGGATGAGAGTGGCCCCTTAGCCTACCACATCACCCTCGTGGAG TTGCTGGCAGCATGCACAGAGGGGAAGAACGTCTACACTGAAATCAAGTGCAATTCCCTT CTGCCCCTGGACGACATAGTGAGGGTGGTGACCCATGATGACTGCATCCCTGAGGTTAAA ATTGCTTATGTGAATTTTGTTAATCACTGTTACGTGGACACAGAAGTGGAAATGAAAGAA ATCTACACAAGTAACCACATTTGGAAATTATTTGAGAACTTCTTGGTGGATATGGCAAGG GTTTGCAACACAACCACAGACAGGAAGCATGCAGACACCTTTTTGGAGAAGTGTGTTACT GAGTCAATAATGAACATTGTGAGCGGCTTCTTTAATTCACCCTTTTCAGACAACAGTACC AGCCTCCAGACACATCAGCCAGTTTTTATTCAGCTGCTCCAGTCTGCCTTCAGAATTTAT AATTGCACCTGGCCAAATCCAGCCCAGAAAGCCTCAGTGGAGTCCTGTATCAGAACTTTG GCTGAAGTGGCAAAGAATCGTGGAATTGCCATTCCAGTGGATTTGGACAGCCAAGTGAAT ACTCTTTTCTTGAAGAGTCATTCAAATATGGTGCAGAGAGCGGCCATGGGCTGGAGACTA TCAGCTCGCTCTGGACCACGCTTTAAGGAAGCTCTTGGAGGGCCTTCTTGGGATTACAGA AATATTATTGAAAAGTTACAGGATGTAGTGGCCTCCTTGGAGCAACAATTCAGCCCGATG ATGCAGGCTGAATTCTCAGTGTTGGTTGATGTGTTGTACAGCCCAGAACTGCTGTTTCCC GAGGGAAGCGATGCGAGAATAAGATGTGGCGCTTTCATGTCGAAGTTGATTAATCATACA AAGAAGCTGATGGAAAAAGAAGAAAAATTGTGCATTAAAATTCTTCAGACTTTACGAGAA ATGCTAGAGAAGAAAGACAGCTTTGTGGAAGAGGGCAATACATTAAGAAAAATCCTCCTG AATCGATACTTTAAAGGTGATTACGGAGTCTCTATAAATGGACACCTCTCTGGAACCTAC TGCAAAACCGCACAGGTGGGAGGAAGCTTTTCTGGACAAGATTCAGATAAGATGGGGATA TCCATGTCAGATATTCAGTGTCTCCTGGATAAAGAAGGTGCATCTGAACTTGTCATCGAT GTTATAGTGAATACCAAAAATGACAGAATTTTTTCAGAAGGCATCTTACTTGGCATTGCC TTGCTGGAAGGAGGAAACACACAAACTCAGTATTCCTTCTACCAGCAGTTACATGAACAA AAAAAATCAGAAAAATTCTTCAAAGTTCTCTACGACCGAATGAAGGCTGCTCAGAAAGAG ATAAGATCAACAGTGACAGTTAACACCATCGACTTAGGTAACAAGAAAAGGGATGATGAC ACAGAACTGATGACATCTGGCCCACGGATGAGAGTAAGGGATTCATCATTACATTTAAAA GAGGGAATGAAAGGGCAGTTAACAGAAGCTTCTTCGGCCACATCCAAAGCATACTGTGTA TACAGAAGAGAAATGGATCCAGAAATAGACATCATGTGTGCAGGACCCGAAGCAGGAAAT GCCGAGGATAGGTCCACCGAGGAAGTCACAATGAGCCCTGCCATTGCCATCATGCAGCCG ATTTCGAGGTTTCTGCAGTTACTCTGTGAGAATCATAACCGGGAGCTGCAGCACTTCCTG AGGAATCAAAACAACAAAACCAATTACAACCTTGTCTGTGAGACCCTTCAGTTTTTGGAT TGCATTTGTGGAAGTACAACAGGAGGCCTGGGACTCTTGGGTCTCTACATCAACGAGAAG AATGTAGTGCTGGTCAACCAGACTCTGGAGAGCTTGACTGAGTATTGCCAGGGTCCATGC CATGAAAATCAGACATGTATTGCTACTCATGAATCTAATGGAATTGATATCATCATTGCT TTGATTCTAAATGACATAAACCCTCTTGGTAAATATCGAATGGACCTGGTGCTCCAACTA AAGAACAATGCCCCCAAGCTTTTGCTGGCCATCATGGAAAGCAGACATGACAGCGAGAAT GCAGAAAGGATTCTTTTCAACATGAGACCCAGAGAACTGGTGGATGTGATGAAGAATGCC TATAATCAAGGATTGGAATGCGATCATGGGGATGATGAGGGCGGAGATGATGATGTTTCC CCAAAGGATGTTGGACACAATATCTATATCCTGGCCCATCAGTTGGCCCGCCACAACAAA CTTTTACAGCAGATGCTCAAACCAGGATCCGATCCAGATGATGGCGATGAAGCCTTGAAG TATTATGCCAACCATACTGCACAGATCGAGATTGTTCGACATGACAGGACAATGGAACAA ATAGTATTTCCTGTCCCCAATATATGTGAATACCTCACGCGAGAATCCAAGTGTCGCGTA TTCAACACCACGGAGAGGGATGAACAGGGAAGTAAAGTGAATGACTTTTTCCAGCAAACT GAAGATCTCTACAATGAGATGAAGTGGCAGAAGAAAATCAGGAGTAATCCTGCCCTGTTC TGGTTCTCAAGGCATATTTCTCTTTGGGGGAGCATCTCGTTCAACCTGGCTGTGTTCATC AACTTAGCTGTGGCTCTCTTCTACCCATTTGGGGACGATGGAGATGAAGGTACTCTTTCA CCGATGTTCTCAATTCTGCTTTGGATAGCAGTGGCAATCTGCACATCTATGCTGTTTTTC TTCTCCAAGCCTGTGGGTATTCGGCCATTTCTTGTGTCAGTAATGCTCAGATCAATATAT ACAATAGGTCTTGGGCCTACATTAATACTTCTTGGTGCAGCAAATCTTTGTAATAAAATA GTGTTTCTGGTGAGTTTTGTTGGAAATCGGGGTACGTTCACCCGAGGCTACCGAGCGGTC ATCCTGGATATGGCCTTTCTCTACCACGTGGCGTATGTCCTGGTTTGCATGCTGGGCCTC TTTGTCCATGAATTCTTCTATAGCTTCCTGCTTTTTGATTTGGTATATAGAGAAGAGACC CTGCTCAATGTCATAAAAAGTGTCACACGGAACGGCCGATCCATTATTCTAACTGCAGTT CTTGCCCTCATCCTTGTCTACCTGTTTTCCATTATTGGGTTCCTTTTTCTGAAGGATGAC TTCACTATGGAGGTGGATAGGCTGAAAAACAGAACTCCCATCACAGGTAGCAATGCAGTT CCTACGATGACTTTAACTTCAATCCTGAGTACGTGCGAAAAGGACAACTGCTCACCTACA ATACCAGCTTCAAATACAGCTGATGAGGAATATGAAGATGGGATTGAAAGGACATGTGAC ACTCTTCTAATGTGCATTGTGACCGTCCTGAACCAGGGCCTCAGGAATGGTGGAGGCGTG GGCGACGTGCTGAGAAGACCATCAAAAGATGAGCCCTTGTTTGCTGCTCGTGTGGTTTAT GACCTTCTTTTTTATTTCATTGTCATCATTATCGTTCTGAACTTGATTTTTGGGGTTATC ATTGATACTTTTGCTGATCTCAGAAGTGAAAAACAGAAAAAAGAAGAAATTCTAAAGACC ACCTGCTTCATCTGTGGACTCGAGAGGGACAAGTTTGATAATAAAACGGTTTCTTTTGAG GAACACATCAAGTCAGAACACAATATGTGGCATTATTTGTACTTCCTAGTCCTGGTGAAG GTGAAAGACCCAACTGAATATACCGGACCTGAAAGTTACGTGGCTCAAATGATTGTGGAG AAGAATTTGGACTGGTTTCCTCGGATGCGAGCCATGTCCCTTGTTAGCAGTGAAGGTGAC AGCGAGCAAAATGAGGTTCGGAACCTGCAGGAGAAGCTGGAGTCAACCATGAGTCTGGTC AAACAGCTGTCCAGTCAGCTGGCAGAGCTCAAGGAGCAGATGACAGAACAAAGGAAGAAT AAGCAGAGACTGGGCTTTCTCGGATCAAACACACCCCATGTGAATCATCACATGCCACCA CACTGA 2701 307820.0 6.36 2228-2248 2261-2281 2308-2328 2352-2372 2395-2415 2521-2541 None >Inositol 1,4,5-trisphosphate receptor type 2 MSDKMSSFLYIGDIVSLYAEGSVNGFINTLGLVDDRCVVHPEAGDLANPPKKFRDCLFKV CPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAELEQKQNESENKKLLGEIVKYSNV IQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGG KVVLMPVNAGQPLHASNIELLDNPGCKEVNAVNCNTSWKITLFMKYSSYREDVLKGGDVV RLFHAEQEKFLTCDEYEKKQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWN SLFRFKHLATGNYLAAELNPDYRDAQNEGKNVRDGDLPASKKKRQAGEKIMYTLVSVPHG NDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTDEERPVMLKIGTC QTKEDKEAFAIVSVPPSEVRDLDFANDANKVLATTVKKLENGTITQNERRFVTKLLEDLI FFVADVPNNGQDVLDVLITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLED LGDQRYAPYKYMLRLCYRVLGHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLH NNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNTTAIPVTQELICKFMLSPG NADILIQTKLVSMQGDNPMESAILSDDIDEEEVWLYWIDSNKEPHGKAIRHLAQEAKEGT KADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCMSDESLPFDLRASFCR LMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSITDSSRNDMKRKFALTMEFVEE YLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPM SSYFERLSKFQDGGNNVMRTIHGVGEMMTQMVLSRGSIFPMSVPDIQPSLHPSKQGSPTD HEDVTVMDTKLKIIEILQFILSVRLDYGISYMLSIYKKEFGENNGNAEMSTNGSPDTLLP SAIVPDIDEIAAQAETMFAGRKEKNPVQLDDEGGRTFLRVLIHLIMHDYPPLLSGALQLL FKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSSSYENGE MGENQVKGGEEPIEDSNILSPVQDGTKKPQIDSNKSNNYRIVKEILIRLSKLCVQNKKCR NQHQRLLKNMGAHSVVLDLLQIPYEKNDEKMNEVMNLAHTFLQNFCRGNPQNQVLLHKHL NLFLTPGLLEAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKAD GKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLHMMCSERDRGDESGPLAYHITLVE LLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKE IYTSNHIWKLFENFLVDMARVCNTTTDRKHADTFLEKCVTESIMNIVSGFFNSPFSDNST SLQTHQPVFIQLLQSAFRIYNCTWPNPAQKASVESCIRTLAEVAKNRGIAIPVDLDSQVN TLFLKSHSNMVQRAAMGWRLSARSGPRFKEALGGPSWDYRNIIEKLQDVVASLEQQFSPM MQAEFSVLVDVLYSPELLFPEGSDARIRCGAFMSKLINHTKKLMEKEEKLCIKILQTLRE MLEKKDSFVEEGNTLRKILLNRYFKGDYGVSINGHLSGTYCKTAQVGGSFSGQDSDKMGI SMSDIQCLLDKEGASELVIDVIVNTKNDRIFSEGILLGIALLEGGNTQTQYSFYQQLHEQ KKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGNKKRDDDTELMTSGPRMRVRDSSLHLK EGMKGQLTEASSATSKAYCVYRREMDPEIDIMCAGPEAGNAEDRSTEEVTMSPAIAIMQP ISRFLQLLCENHNRELQHFLRNQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEK NVVLVNQTLESLTEYCQGPCHENQTCIATHESNGIDIIIALILNDINPLGKYRMDLVLQL KNNAPKLLLAIMESRHDSENAERILFNMRPRELVDVMKNAYNQGLECDHGDDEGGDDDVS PKDVGHNIYILAHQLARHNKLLQQMLKPGSDPDDGDEALKYYANHTAQIEIVRHDRTMEQ IVFPVPNICEYLTRESKCRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRSNPALF WFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLSPMFSILLWIAVAICTSMLFF FSKPVGIRPFLVSVMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNRGTFTRGYRAV ILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAV LALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPITGSNAVPTMTLTSILSTCEKDNCSPT IPASNTADEEYEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRRPSKDEPLFAARVVY DLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFE EHIKSEHNMWHYLYFLVLVKVKDPTEYTGPESYVAQMIVEKNLDWFPRMRAMSLVSSEGD SEQNEVRNLQEKLESTMSLVKQLSSQLAELKEQMTEQRKNKQRLGFLGSNTPHVNHHMPP H AAL39077.1 Q8WN96 ITPR2_BOVIN AF402600 ITPR2