| Identification |
|---|
| BMDB Protein ID
| BMDBP01335 |
| Secondary Accession Numbers
| None |
| Name
| Prostaglandin D2 receptor |
| Synonyms
|
Not Available
|
| Gene Name
| PTGDR |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in G-protein coupled receptor protein signalin |
| Specific Function
| Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity). |
| Pathways
|
- Intracellular Signalling Through PGD2 receptor and Prostaglandin D2
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 10 |
| Locus
| Not Available |
| SNPs
| PTGDR |
| Gene Sequence
|
>1086 bp
ATGAGGCCGCTGTTTTACCGCTGCCACAATACCACGTCGGTGGAGAAGGGCAATTCGGCG
ACGATGGGCGGGGTGCTCTTCAGCACGGGCCTCGTGGGCAACCTGCTGGCCCTGGGACTC
CTGGCGCGCTCCGGTCTGGGGTCGTGCCCGCCGCGCTCGCCGCGCCCGCCGCCCTCCGTC
TTCTACGTGCTGGTGTTCGGCCTGACGATCACAGACCTCCTGGGCAAGTGTCTAGTGAGC
CCCTTCGTGCTGTCCGCCTACGCGCAGAACCGAAGCCTGCGGGAGCTGGTGCCCGGATCG
GACAGCTCTCTGTGCCAAGCCTTCGCCTTCATCATGTCCTTCTTCGGGCTCGCCTCGACG
CTGCAGCTGCTGGCCATGGCCCTGGAGTGCTGGCTCTCCCTGGGGCACCCCTTCTTCCAT
CGACGGCACCTCACCCCGCGCCGGGGTGCAATGGTGGCGCCGGTGGTGGGCGCCTTCTGC
CTCGCTTTCTGCGCGCTGCCCTTGGTGGGCTTTGGGAAGTTTGTGCAGTACTGCCCTGGC
ACCTGGTGCTTCTTCCAGATGGTCCACGAGGAGCGCTCGCTGTCGGTGCTGAGCTACTCG
GTGCTCTACGCCAGCCTCATGCTGCTGCTGGTGCTCGCCATCGTGCTGTGCAACCTGAGC
GCCATGCGCAACCTCTATGCCATGCACCTGCGGCTGCGGGGACTCCTGCGCCCTGGCTCC
AGGGAACGCGCCGAGCCGGGCGCCGGCGAGAGGGAGGCGACCCCGCTGCACCTGGAGGAG
CTGGATCACCTCCTGCTGCTAGCCCTCATGACGGTGCTCTTCACCATGTGCTCCCTGCCT
TTAATTTATCGTGCTTACTATGGAGCGTTTAAAGCTGTTCCTGAGCAAAATGGAACCACT
GAAGAAACTGAAGACCTCCGAGCCTTGCGCTTTCTCTCTGTGATCTCAATTGTGGACCCT
TGGATTTTCATCATTTTCAGAACATCAGTGTTTCGAATGTTTTTTCGCAAGATTTTCATA
AGGCCCCTTATATATAGAAATTGGCACAGCAATTCTTGCCAAACTAACATGGAATCCAGT
CTATAA
|
| Protein Properties |
|---|
| Number of Residues
| 361 |
| Molecular Weight
| 40372.0 |
| Theoretical pI
| 9.04 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 22-42
- 59-79
- 108-128
- 151-171
- 196-216
- 263-283
- 311-331
|
| Protein Sequence
|
>Prostaglandin D2 receptor
MRPLFYRCHNTTSVEKGNSATMGGVLFSTGLVGNLLALGLLARSGLGSCPPRSPRPPPSV
FYVLVFGLTITDLLGKCLVSPFVLSAYAQNRSLRELVPGSDSSLCQAFAFIMSFFGLAST
LQLLAMALECWLSLGHPFFHRRHLTPRRGAMVAPVVGAFCLAFCALPLVGFGKFVQYCPG
TWCFFQMVHEERSLSVLSYSVLYASLMLLLVLAIVLCNLSAMRNLYAMHLRLRGLLRPGS
RERAEPGAGEREATPLHLEELDHLLLLALMTVLFTMCSLPLIYRAYYGAFKAVPEQNGTT
EETEDLRALRFLSVISIVDPWIFIIFRTSVFRMFFRKIFIRPLIYRNWHSNSCQTNMESS
L
|
| External Links |
|---|
| GenBank ID Protein
| AAI40595.1 |
| UniProtKB/Swiss-Prot ID
| A5D7K8 |
| UniProtKB/Swiss-Prot Entry Name
| PD2R_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC140594 |
| GeneCard ID
| PTGDR |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
