| Identification |
|---|
| BMDB Protein ID
| BMDBP01342 |
| Secondary Accession Numbers
| None |
| Name
| P2Y purinoceptor 1 |
| Synonyms
|
Not Available
|
| Gene Name
| P2RY1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in purinergic nucleotide receptor activity, G- |
| Specific Function
| Receptor for extracellular adenine nucleotides such as ADP (PubMed:7626079). In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 1 |
| Locus
| Not Available |
| SNPs
| P2RY1 |
| Gene Sequence
|
>1122 bp
ATGACCGAGGTGCTGTGGCCGGCGGTCCCCAACGGGACGGACACTGCCTTCCTTGCCGAC
CCTGGTTCGCCCTGGGGAAACAGCACAGTGACTTCCACCGCCGCCGTCGCCAGCCCGTTC
AAATGCGCGCTGACCAAGACAGGCTTCCAGTTCTACTACCTGCCAGCTGTCTACATCTTG
GTGTTCATTATCGGCTTCCTGGGCAACAGCGTGGCCATCTGGATGTTCGTCTTCCACATG
AAGCCGTGGAGCGGCATCTCCGTGTACATGTTCAACTTGGCCCTGGCCGACTTCTTGTAC
GTGCTGACTCTGCCGGCGCTCATCTTCTACTACTTCAATAAGACCGACTGGATCTTTGGG
GATGCCATGTGCAAGCTGCAGAGGTTCATCTTCCACGTGAACCTCTATGGCAGCATCTTA
TTCCTGACCTGCATTAGCGCGCACCGGTACAGCGGCGTGGTGTACCCGCTCAAGTCCCTG
GGTAGGCTCAAGAAGAAGAACGCGGTCTATATTAGCGTGCTGGTGTGGCTCATCGTGGTG
GTGGGCATCTCCCCCATCCTCTTCTACTCTGGCACCGGGATCCGGAAAAACAAAACCATC
ACCTGCTATGACACCACCTCAGACGAGTACCTGCGAAGTTATTTCATCTATAGTATGTGC
ACGACCGTGGCCATGTTCTGTGTCCCCTTGGTGCTGATTTTGGGCTGTTACGGATTAATT
GTGAGAGCTCTGATTTACAAAGACCTGGACAATTCGCCTCTGAGGAGGAAATCCATTTAC
CTGGTGATTATTGTACTGACTGTTTTTGCTGTGTCTTACATCCCTTTCCACGTGATGAAA
ACAATGAATTTGAGGGCCCGGCTGGATTTTCAGACCCCAGAAATGTGTGCTTTCAATGAT
AGGGTGTATGCCACTTATCAGGTGACAAGAGGTCTAGCAAGTCTCAACAGTTGTGTGGAC
CCCATTCTCTATTTCTTGGCAGGAGATACTTTCAGAAGGAGACTCTCCCGAGCCACCAGG
AAGGCTTCCAGAAGAAGTGAGGCAAACTTGCAGTCCAAGAGTGAAGACATGACACTCAAT
ATTTTATCAGAGTTCAAGCAGAATGGAGATACAAGCTTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 373 |
| Molecular Weight
| 42288.0 |
| Theoretical pI
| 9.54 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 52-74
- 88-109
- 126-147
- 167-188
- 215-237
- 261-284
- 304-325
|
| Protein Sequence
|
>P2Y purinoceptor 1
MTEVLWPAVPNGTDTAFLADPGSPWGNSTVTSTAAVASPFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAVYISVLVWLIVV
VGISPILFYSGTGIRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPEMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILSEFKQNGDTSL
|
| External Links |
|---|
| GenBank ID Protein
| CAA60958.1 |
| UniProtKB/Swiss-Prot ID
| P48042 |
| UniProtKB/Swiss-Prot Entry Name
| P2RY1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| X87628 |
| GeneCard ID
| P2RY1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
