| Identification |
|---|
| BMDB Protein ID
| BMDBP01864 |
| Secondary Accession Numbers
| None |
| Name
| Gamma-aminobutyric acid receptor subunit alpha-3 |
| Synonyms
|
Not Available
|
| Gene Name
| GABRA3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in chloride channel activity |
| Specific Function
| GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| X |
| Locus
| Not Available |
| SNPs
| GABRA3 |
| Gene Sequence
|
>1479 bp
ATGATAATAACACAGATGAGTCAGTTCTACATGGCTGGCCTTGGGCTTCTCTTCCTGATT
AATATTCTCCCTGGAACAACTGGCCAAGTGGAATCAAGACGACAAGAACCTGGGGACTTT
GTGAAGCAGGATATTGGCGGACTCTCTCCAAAGCATGCTCCAGATATTCCTGATGACAGC
ACCGACAACATCACTATCTTCACCAGAATCTTGGATCGTCTTCTGGATGGCTATGACAAT
CGGCTGCGACCTGGGCTTGGAGATGCAGTGACTGAAGTGAAGACTGACATCTATGTGACC
AGTTTTGGCCCTGTGTCAGACACTGACATGGAGTACACCATTGATGTATTTTTTCGACAG
ACATGGCATGATGAAAGACTGAAATTTGATGGACCCATGAAGATCCTTCCACTGAATAAT
CTCCTGGCTAGTAAGATCTGGACCCCTGACACCTTCTTCCACAATGGCAAGAAATCAGTG
GCCCATAACATGACCACACCTAACAAGCTGCTCAGACTGGTGGACAATGGAACCCTCCTC
TACACAATGAGGTTAACAATTCATGCTGAGTGTCCCATGCATTTGGAAGATTTTCCTATG
GATGTGCATGCCTGCCCACTGAAGTTTGGAAGCTATGCCTATACAACAGCTGAAGTCGTT
TATTCTTGGACTCTTGGGAAGAACAAATCTGTGGAAGTGGCGCAAGATGGCTCTCGACTG
AATCAGTATGACCTGCTGGGCCATGTTGTTGGGACAGAAATAATCCGGTCTAGTACAGGA
GAATATGTCGTCATGACAACCCACTTCCACCTCAAGCGAAAAATTGGCTACTTTGTGATC
CAGACCTACTTGCCATGTATCATGACTGTCATCCTGTCACAAGTGTCTTTCTGGCTCAAC
AGAGAGTCTGTCCCTGCCCGCACGGTCTTTGGTGTCACCACTGTTCTCACCATGACCACC
TTGAGTATCAGTGCCAGGAACTCCTTACCTAAAGTGGCATATGCGACGGCCATGGATTGG
TTCATGGCCGTGTGTTATGCCTTTGTATTTTCTGCGCTGATTGAGTTTGCGACCGTGAAC
TACTTCACAAAGCGGAGTTGGGCTTGGGAAGGCAAGAAGGTGCCAGAGGCCCTGGAGATG
AAGAAGAAAACACCAGCAGTCCCGACCAAGAAAACCAGCACCACTTTCAACATCGTGGGA
ACCACCTATCCCATCAACCTGGCCAAGGACACTGAATTCTCTGCCATCTCCAAGGGCGCT
GCTCCAAGCACCTCCTCCACCCCGACAATCATTGCTTCACCCAAGACCACCTGTGTGCAG
GATATCCCGACTGAGACCAAGACCTACAACAGTGTCAGCAAGGTTGACAAGATTTCCCGC
ATCATCTTTCCTGTGCTCTTTGCCATTTTCAATCTGGTCTATTGGGCTACATATGTCAAC
CGGGAGTCAGCTATCAAGGGCATGATCCGCAAACAGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 492 |
| Molecular Weight
| 55284.0 |
| Theoretical pI
| 8.94 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 277-298
- 304-325
- 338-359
- 458-479
|
| Protein Sequence
|
>Gamma-aminobutyric acid receptor subunit alpha-3
MIITQMSQFYMAGLGLLFLINILPGTTGQVESRRQEPGDFVKQDIGGLSPKHAPDIPDDS
TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ
TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL
YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRL
NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN
RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFMAVCYAFVFSALIEFATVN
YFTKRSWAWEGKKVPEALEMKKKTPAVPTKKTSTTFNIVGTTYPINLAKDTEFSAISKGA
APSTSSTPTIIASPKTTCVQDIPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVN
RESAIKGMIRKQ
|
| External Links |
|---|
| GenBank ID Protein
| CAA30925.1 |
| UniProtKB/Swiss-Prot ID
| P10064 |
| UniProtKB/Swiss-Prot Entry Name
| GBRA3_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| X12362 |
| GeneCard ID
| GABRA3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
