| Identification |
|---|
| BMDB Protein ID
| BMDBP02075 |
| Secondary Accession Numbers
| None |
| Name
| Solute carrier family 2, facilitated glucose transporter member 5 |
| Synonyms
|
Not Available
|
| Gene Name
| SLC2A5 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 14 |
| Locus
| Not Available |
| SNPs
| SLC2A5 |
| Gene Sequence
|
>1506 bp
ATGGAGCCGCAGGATCCAGTCAAGAGGGAAGGGAGGCTGACACCCGTGATTGTTCTGGCG
ACACTGATAGCTGCCTTTGGGTCGTCCTTCCAGTATGGGTACAACGTGGCTGCTATTAAC
TCCCCTTCAGAGTTCATGAAAGACTTCTACAACTATACCTACTATGACAGAGTCGGTGAA
TACATGAACGAGTTCTACTTGACCTTGCTGTGGTCGGTTACCGTGTCCATGTTTCCCTTC
GGAGGCTTCCTCGGCTCTCTCATGGTTGGCCCCTTGGTAAATAACTTAGGCAGAAAAGGA
ACCTTGCTGTTCAACAACATCTTCTCCATCGTGCCTGCACTCTTAATGGGATTCAGTGAG
CTCGCCAAGTCATTTGAGATGATAATTGTGGCCAGGGTTTTGGTGGGAATATGTGCAGGT
CTGTCTTCCAATGTCGTCCCCATGTACTTAGGGGAGCTGGCCCCTAAGAACTGGAGGGGG
GCCCTGGGGGTGGTGCCCCAGCTCTTCATCACCATCGGAATCCTTGTGGCCCAGATCTTT
GGTCTTCGGAGTCTCCTGGCAAACGAAGAAGGCTGGCCCATCCTCCTCGGATTGACTGGG
ATCCCCGCTGTGCTGCAGCTCCTCTTCCTGCCCTTCTTCCCTGAGAGTCCCAGGTACCTG
CTGATTCAGAAGAAAGATGAAGCAGCTGCCAAAAGCGCTCTGAGGAGGCTGCGTGGCTGG
CATGACGTGGATGCGGAGATAGAGGAGATCCTGGAGGAGGACAGGGCTGAGAAGGCTGTG
GGCTTCATCTCCGTGCTGAAGCTGTTCAAGATGAGGTCCCTGCGGTGGCAGGTCATCTCC
ATCATCGTCCTCATGGCGGGCCAGCAGCTCTCCGGAGTGAATGCGATCTACTACTACGCA
GACCAGATTTACCTGAGTGCTGGAGTGAATGAGGACGATGTCCAATATGTGACGGCGGGC
ACAGGTGCTGTCAATGTGCTGATAACTGTCTGCGCTATTTTCGTGGTGGAACTAATGGGG
AGGAGATTCCTGCTCCTCCTGGGCTTCTCTGTCTGTTTCACCGCTTGCTGCGTGCTGACG
GGTGCCTTGGCTCTGCAGGACGTGATATCCTGGATGCCCTACGTCAGCATCGCCTGTGTC
ATCTCCTACGTCATAGGGCATGCCCTTGGGCCCAGTCCCATCCCCGCACTGCTGGTCACC
GAGATCTTCCTGCAGTCCTCCCGGCCAGCTGCCTACATGGTGGCGGGTACTGTTCACTGG
CTCTCCAACTTCACTGTGGGCTTGGTCTTCCCATTCATCCAAGTGGGCCTCGGAGCTTAC
AGCTTCGTCATTTTTGCGGTGATATGTCTTCTCACCACCGTCTACATCTTCCTGATCATC
CCTGAAACCAAGTCCAAGACCTTCATAGAAATCAATCGGATCTTCATCAAGATGAACAAA
GTGCCAGGGGTGCACCCAGAAAAGGAGGAGCTAAAGGAGTTTCCACCGTCGACTGCAAGG
CAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 501 |
| Molecular Weight
| 55393.0 |
| Theoretical pI
| 6.52 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 19-39
- 69-91
- 99-119
- 127-149
- 162-182
- 193-213
- 278-298
- 314-334
- 343-363
- 372-394
- 413-433
- 440-460
|
| Protein Sequence
|
>Solute carrier family 2, facilitated glucose transporter member 5
MEPQDPVKREGRLTPVIVLATLIAAFGSSFQYGYNVAAINSPSEFMKDFYNYTYYDRVGE
YMNEFYLTLLWSVTVSMFPFGGFLGSLMVGPLVNNLGRKGTLLFNNIFSIVPALLMGFSE
LAKSFEMIIVARVLVGICAGLSSNVVPMYLGELAPKNWRGALGVVPQLFITIGILVAQIF
GLRSLLANEEGWPILLGLTGIPAVLQLLFLPFFPESPRYLLIQKKDEAAAKSALRRLRGW
HDVDAEIEEILEEDRAEKAVGFISVLKLFKMRSLRWQVISIIVLMAGQQLSGVNAIYYYA
DQIYLSAGVNEDDVQYVTAGTGAVNVLITVCAIFVVELMGRRFLLLLGFSVCFTACCVLT
GALALQDVISWMPYVSIACVISYVIGHALGPSPIPALLVTEIFLQSSRPAAYMVAGTVHW
LSNFTVGLVFPFIQVGLGAYSFVIFAVICLLTTVYIFLIIPETKSKTFIEINRIFIKMNK
VPGVHPEKEELKEFPPSTARQ
|
| External Links |
|---|
| GenBank ID Protein
| AAI51531.1 |
| UniProtKB/Swiss-Prot ID
| P58353 |
| UniProtKB/Swiss-Prot Entry Name
| GTR5_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC151530 |
| GeneCard ID
| SLC2A5 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
