| Identification |
|---|
| BMDB Protein ID
| BMDBP02138 |
| Secondary Accession Numbers
| None |
| Name
| Neutral amino acid transporter B(0) |
| Synonyms
|
Not Available
|
| Gene Name
| SLC1A5 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 18 |
| Locus
| Not Available |
| SNPs
| SLC1A5 |
| Gene Sequence
|
>1620 bp
ATGGTGGCCGATCCGCCTAAGGGAGACCCCAAAGGGTACGCGGCGGCGGAACCCACCGCC
AACGGTGTCTCGATGTTGGTCCCCATAGAGGACGTAGGCTCGTTAAAAGGCGGCCGTTGC
GGTTCCGGGGATCAGGTGCGTCGCTGCCTTCGCGCCAACTTGCTGGTGCTGCTGACGGTA
GTGGCCGTGGTGGCCGGCGTGGCGCTGGGGCTGGGGGTCTCGGGAGCCGGCGGCGCGTTC
GCCCTGGGCCCCGCGCGCCTGGAAGCCTTCTCCTTTCCGGGAGAGCTGCTGCTGCGCCTG
TTAAAGATGATCATCTTGCCGCTGGTGGTGTGCAGCTTGATCGGCGGCGCCGCCAGCCTG
GATCCGAGCGCGCTCGGGCGCCTTGGCGCCTGGGCGCTGCTCTTTTTCCTTGTCACCACA
CTGCTAGCGTCGGCGCTCGGCGTGGGCTTGGCGCTCGCGCTGCAGCCGGGCGCCGCCTTC
GCCGCCATCAACACCTCGGTCGGGGCCCCGGTGGAAGAGGCCCCCAGCAAGGAGGTGCTC
GATTCGTTCCTGGATCTTGTGAGAAATATTTTCCCCTCCAACCTGGTATCTGCAGCCTTC
CGCTCATACACTACCTCCTATAAGGAGAGATTGTTCAACGGCACTCTGGTGAAGGTGCCC
ACTGGGGGCGAGGTTGAGGGTATGAACATTCTGGGCCTGGTGGTGTTTGCCATCATCTTT
GGTGTGGCCCTGCGGAAGTTGGGGCCCGAGGGAGAGCTGCTCATTCGCTTCTTCAACTCC
TTCAATGATGCCACCATGGTGCTGGTCTCCTGGATCATGTGGTACGCCCCTGTGGGAATC
TTGTTCCTGGTGGCCGGCAAGATTGTGGAGATGGAGAACGTGGGGCTGCTCTTTGCTAGT
CTCGGCAAATACATCCTGTGCTGCCTGCTCGGCCATGCCATCCATGGGCTCCTGACACTG
CCCCTCATCTACTTTCTCTTCGCCCGCAAGAACCCCTACCGCTTCCTGTGGGGCATCATG
ACGCCGCTGGCCACCGCCTTCGGGACCTCCTCCAGCTCCGCCACGCTGCCGCTGATGATG
AAGTGTGTGGAGGAGAAGAATGGAGTGGCCAGACACATCAGCCGCTTCATTCTGCCCATC
GGTGCCACGGTCAACATGGACGGTGCCGCCCTCTTCCAGTGTGTGGCTGCAGTGTTCATT
GCACAGCTCAACCACCGGTCCTTGGACTTCGTGAAGATTATCACCATCCTGGTCACGGCC
ACAGCATCCAGTGTGGGTGCGGCGGGCATCCCATCTGGAGGGGTGCTCACTCTGGCCATC
ATCCTCGAGGCGGTCAACCTGCCGGTTCACGACATCTCCTTGATCTTGGCCGTGGACTGG
CTAGTGGACCGGTCCTGTACCGTCCTCAACGTGGAAGGTGATGCCTTTGGGGCGGGACTC
CTCCAGAGTTACCTGGATCGCACAGAGAACTGCAACTCCGTGCCGGAGCTGATCCAGGTG
AAGAGTGAGATGCCCCTGGCCGCGCTGCCGGTCCCCGGCGAGGAGGGGAACCCTCTCCTC
AAAGGCTGCCCGGGACCTGCTGGGGATGCTGACACCTGTGAGAAGGAATCAGTCATGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 539 |
| Molecular Weight
| 56448.0 |
| Theoretical pI
| 5.48 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 53-82
- 96-117
- 132-154
- 224-247
- 257-284
- 306-327
- 373-399
- 460-481
|
| Protein Sequence
|
>Neutral amino acid transporter B(0)
MVADPPKGDPKGYAAAEPTANGVSMLVPIEDVGSLKGGRCGSGDQVRRCLRANLLVLLTV
VAVVAGVALGLGVSGAGGAFALGPARLEAFSFPGELLLRLLKMIILPLVVCSLIGGAASL
DPSALGRLGAWALLFFLVTTLLASALGVGLALALQPGAAFAAINTSVGAPVEEAPSKEVL
DSFLDLVRNIFPSNLVSAAFRSYTTSYKERLFNGTLVKVPTGGEVEGMNILGLVVFAIIF
GVALRKLGPEGELLIRFFNSFNDATMVLVSWIMWYAPVGILFLVAGKIVEMENVGLLFAS
LGKYILCCLLGHAIHGLLTLPLIYFLFARKNPYRFLWGIMTPLATAFGTSSSSATLPLMM
KCVEEKNGVARHISRFILPIGATVNMDGAALFQCVAAVFIAQLNHRSLDFVKIITILVTA
TASSVGAAGIPSGGVLTLAIILEAVNLPVHDISLILAVDWLVDRSCTVLNVEGDAFGAGL
LQSYLDRTENCNSVPELIQVKSEMPLAALPVPGEEGNPLLKGCPGPAGDADTCEKESVM
|
| External Links |
|---|
| GenBank ID Protein
| AAK83490.1 |
| UniProtKB/Swiss-Prot ID
| Q95JC7 |
| UniProtKB/Swiss-Prot Entry Name
| AAAT_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AY039236 |
| GeneCard ID
| SLC1A5 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
