| Identification |
|---|
| BMDB Protein ID
| BMDBP02180 |
| Secondary Accession Numbers
| None |
| Name
| Sodium- and chloride-dependent GABA transporter 2 |
| Synonyms
|
Not Available
|
| Gene Name
| SLC6A13 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in gamma-aminobutyric acid:sodium symporter ac |
| Specific Function
| Sodium-dependent GABA and taurine transporter. In presynaptic terminals, regulates GABA signaling termination through GABA uptake. May also be involved in beta-alanine transport (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| SLC6A13 |
| Gene Sequence
|
>1809 bp
ATGGATAGCAGGGTCTCGGGCACCACCAGTAATGGCGAGACCAAACCAGTGTGCCCAGGC
CTGGAAAAGGCGGCGGAGGATGGTGCCCTGCAGCGAGAGCAGTGGAGCAACAAGATGGAG
TTCCTGCTGTCCGTGGCCGGGGAGATCATTGGGCTGGGCAACGTCTGGAGGTTCCCCTAC
CTCTGCTACAAAAACGGGGGAGGTGCCTTCTTCATCCCCTACCTCATCTTCCTCTTTACC
TGCGGCATTCCTGTCTTCCTCCTGGAGACGGCGCTGGGCCAGTACACCAGTCAGGGGGGC
ATCACTGCCTGGAGGAAGATCTGCCCCATCTTTGAGGGCATTGGCTACGCCTCCCAGATG
ATCGTCACCCTCCTCAACATCTACTACATCATTGTCCTGGCCTGGGCCCTCTTCTACCTC
TTCAGCAGCTTTACCATCGACCTGCCCTGGGGGAGCTGCCGCCACGACTGGAACACGGAG
CGCTGCGTGGAGTTCCAGAGGACCAATGGCTCTCTGAATGCGACCGCTGAGAATGCCACC
TCTCCCGTCATCGAGTTCTGGGAGCGGCGGGTCCTGAAGATCTCAGAGGGCATCCAGCAC
CTGGGGGCCCTGCGCTGGGAGCTGGCCCTGTGCCTCCTGCTTGCCTGGGTCGTCTGCTAC
TTCTGCATCTGGAAGGGCGTCAAGTCCACGGGCAAGGTGGTGTACTTCACGGCCACCTTC
CCTTACCTCATGCTGGTGGTCCTATTGATTCGAGGGGTGACGCTGCCCGGGGCAGCGCAA
GGAATTCAGTTCTACCTGTACCCAAACCTCACGCGTCTGTGGGACCCCCAGGTGTGGATG
GACGCGGGCACCCAGATCTTCTTCTCCTTTGCCATCTGCCTAGGGTGCCTGACGGCCCTG
GGCAGCTACAACAAGTATCACAACAACTGCTACAGGGACAGCATCGCGCTCTGCTTCCTC
AACAGCGGCACCAGCTTCGTGGCCGGGTTTGCCATCTTCTCCATCCTGGGCTTCATGTCC
CAAGAGCAGGGGGTGCCCATCTCTGAGGTGGCCGAGTCAGGCCCTGGCCTGGCCTTCATT
GCCTACCCCCGGGCTGTGGTGATGTTGCCCTTCTCGCCCCTCTGGGCCTGCTGCTTCTTC
TTCATGGTCGTCCTCCTGGGACTGGACAGCCAGTTCGTGTGTGTGGAAAGCCTGGTGACG
GCGCTGGTGGACATGTATCCCCGTGTGTTCCGCAAGAAGAACCGCAGGGAGGTCCTCATT
CTGGGGGTATCTGTCACCTCCTTCCTCGTCGGGCTGGTCATGCTCACAGAGGGCGGCATG
TACGTGTTCCAGCTCTTTGACTACTATGCAGCCAGCGGCATGTGCCTGCTGTTCGTGGCT
ATCTTTGAGTCCTTCTGCGTGGCGTGGGCCTATGGAGCTGGGCGCTTTTATGACAACATC
GAGGACATGATTGGGTATAGGCCGTGGCCTCTCATCAAATACTGTTGGCTCTTCCTCACA
CCGGCTGTGTGCACAGCCACCTTCCTCTTCTCCCTGATCAAGTACACCCCGCTGACCTAC
AACAAGAAGTACAAATACCCGTGGTGGGGCGATGCCCTGGGCTGGCTCCTGGCCCTCTCC
TCCATGGTCTGCATTCCTGCCTGGAGCTGCTACAAACTCAGCACCCTCAAGGGGTCTTTC
AGAGAGAGAGTTCGCCAGCTCCTGTGCCCAGCCAAGGACCTTCCCCAGGGGCACCGAGAA
GGACCCTCCGCCCCGGCCACACCCAGGACATCACTTCTCATCCTCACCGAGCTGGAGCCT
CACCACTAG
|
| Protein Properties |
|---|
| Number of Residues
| 602 |
| Molecular Weight
| 67788.0 |
| Theoretical pI
| 7.82 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 41-61
- 68-88
- 121-141
- 207-227
- 233-253
- 282-302
- 319-339
- 366-386
- 418-438
- 453-473
- 490-510
- 528-548
|
| Protein Sequence
|
>Sodium- and chloride-dependent GABA transporter 2
MDSRVSGTTSNGETKPVCPGLEKAAEDGALQREQWSNKMEFLLSVAGEIIGLGNVWRFPY
LCYKNGGGAFFIPYLIFLFTCGIPVFLLETALGQYTSQGGITAWRKICPIFEGIGYASQM
IVTLLNIYYIIVLAWALFYLFSSFTIDLPWGSCRHDWNTERCVEFQRTNGSLNATAENAT
SPVIEFWERRVLKISEGIQHLGALRWELALCLLLAWVVCYFCIWKGVKSTGKVVYFTATF
PYLMLVVLLIRGVTLPGAAQGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTAL
GSYNKYHNNCYRDSIALCFLNSGTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFI
AYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREVLI
LGVSVTSFLVGLVMLTEGGMYVFQLFDYYAASGMCLLFVAIFESFCVAWAYGAGRFYDNI
EDMIGYRPWPLIKYCWLFLTPAVCTATFLFSLIKYTPLTYNKKYKYPWWGDALGWLLALS
SMVCIPAWSCYKLSTLKGSFRERVRQLLCPAKDLPQGHREGPSAPATPRTSLLILTELEP
HH
|
| External Links |
|---|
| GenBank ID Protein
| AAI42277.1 |
| UniProtKB/Swiss-Prot ID
| A5PJX7 |
| UniProtKB/Swiss-Prot Entry Name
| S6A13_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC142276 |
| GeneCard ID
| SLC6A13 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
